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IONS

Ionis Pharmaceuticals

$44.26

1.35 (3.15%)

16:46
04/21/17
04/21
16:46
04/21/17
16:46

Ionis Pharmaceuticals files to sell common stock, no amount given

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IONS Ionis Pharmaceuticals
$44.26

1.35 (3.15%)

03/17/17
GSCO
03/17/17
NO CHANGE
Target $108
GSCO
Buy
AveXis price target raised to $108 on higher confidence in AVXS-101 at Goldman
After AveXis (AVXS) reported results for its Phase 1 study of AVXS-101 in spinal muscular atrophy, Goldman Sachs analyst Salveen Richter said data for the treatment continues to impress and increased his probability of success for the drug to 85% from 65% previously. The analyst, who views AVXS-101 as a key competitive threat to Biogen (BIIB) and Ionis' (IONS) Spinraza as the potential first-line treatment for SMA, raised his price target on AveXis to $108 from $91 and keeps a Buy rating on the shares.
03/13/17
WELS
03/13/17
NO CHANGE
WELS
Ionis Pharma should be bought after negative note, says Wells Fargo
Wells Fargo recommends that investors buy Ionis "ahead of multiple upcoming value drivers" Although another firm on Friday called Ionis' antisense platform a "mirage," that has not realized value, four products that use the platform have been approved, and analysts expect the company to generate $440M in revenue this year, Wells stated. The firm thinks that the company's results can beat expectations.
03/10/17
03/10/17
DOWNGRADE

On The Fly: Top five analyst downgrades
Catch up on today's top five analyst downgrades with this list compiled by The Fly: 1. Dollar General (DG) downgraded to Neutral from Buy at Buckingham with the firm's analyst saying the environment has become more difficult since the bullish analyst day last spring. The firm's analyst said shares do not appear to fully factor in sales and margin challenges and sees risk to Street expectations. 2. MEDNAX (MD) downgraded to Neutral from Overweight at JPMorgan with analyst Gary Taylor citing valuation following the recent rally in the shares. The analyst says he can't with confidence bump up his $69 price target given the multi-year slowdown of organic growth and its high Medicaid payor exposure. 3. Loxo Oncology (LOXO) downgraded to Neutral from Buy at Citi with analyst Yigal Nochomovitz saying the stock is now fairly valued. The reflect the equity financing in January which expanded the share count and rising R&D spend, the analyst cut his price target for the shares to $45 from $49. He believes, however, that Loxo management is executing the business plan well. 4. Kimberly-Clark (KMB) downgraded to Hold on competition, valuation at Societe Generale with analyst Iain Simpson saying price competition in the U.S. has picked up as P&G is becoming more aggressive with its mid-tier Luvs and competition in Brazil and China remains "tough." The analyst expects cost cutting to drive margins and views cash returns as "robust," but said valuation has caught up with fundamentals. 5. Ionis Pharmaceuticals (IONS) downgraded to Sell from Neutral at Goldman with analyst Salveen Richter saying Ionis has a "lackluster" track record of developing successful drugs and ongoing toxicity across multiple drugs. If volanesorsen is approved for FCS, Richter expects safety/compliance issues and the launch focus on specialists will result in limited returns, similar to drug Kynamro for high cholesterol. This list is just a portion of The Fly's full analyst coverage. To see The Fly's full Street Research coverage, click here.
03/10/17
GSCO
03/10/17
DOWNGRADE
Target $25
GSCO
Sell
Ionis Pharmaceuticals downgraded to Sell from Neutral at Goldman
Goldman analyst Salveen Richter downgraded Ionis Pharmaceuticals to Sell and lowered its price target to $25 from $28. The analyst commented Ionis has a "lackluster" track record of developing successful drugs and ongoing toxicity across multiple drugs. If volanesorsen is approved for FCS, Richter expects safety/compliance issues and the launch focus on specialists will result in limited returns, similar to drug Kynamro for high cholesterol.

TODAY'S FREE FLY STORIES

MFSF

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REGN

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LPNT

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BBBY

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BBRY

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BAC

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C

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GS

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16:39
06/23/17
06/23
16:39
06/23/17
16:39
General news
Moody's raises Greece rating to Caa2 from Caa3, outlook to positive from stable »

Moody's has upgraded…

CFCO

CF Corporation

$11.42

-0.04 (-0.35%)

16:38
06/23/17
06/23
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16:38
Hot Stocks
Breaking Hot Stocks news story on CF Corporation »

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AKS

AK Steel

$6.65

0.35 (5.56%)

, X

U.S. Steel

$22.25

1.18 (5.60%)

16:34
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General news
On The Fly: Top stock stories for Friday »

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AKS

AK Steel

$6.65

0.35 (5.56%)

X

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$22.25

1.18 (5.60%)

PTLA

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$56.13

17.88 (46.75%)

BAC

Bank of America

$22.82

-0.11 (-0.48%)

C

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$63.41

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GS

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$217.19

-2.58 (-1.17%)

JPM

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$86.86

-0.16 (-0.18%)

MS

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WFC

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FMC

FMC Corporation

$74.78

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Options
Preliminary option volume of 15.0M today »

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ESNC

EnSync

$0.33

0.0151 (4.79%)

16:25
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Syndicate
Breaking Syndicate news story on EnSync »

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PTLA

Portola Pharmaceuticals

$56.13

17.88 (46.75%)

16:25
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06/23
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16:25
Conference/Events
Portola Pharmaceuticals hold a conference call »

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DTE

DTE Energy

$108.89

-0.69 (-0.63%)

16:24
06/23/17
06/23
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16:24
Earnings
DTE Energy backs FY17 operating EPS view $5.15-$5.46, consensus $5.33 »

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$NSD

NASDAQ Market Internals

16:17
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NASDAQ market internals summary »

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VHI

Valhi Inc

$3.29

0.14 (4.44%)

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Valhi Inc termiantes purchase deal for sale of Waste Control Specialists »

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$NYE

NYSE Market Internals

16:16
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Technical Analysis
NYSE market internals summary »

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GBL

GAMCO Investors

$29.63

-0.24 (-0.80%)

, LSXMA

Liberty SiriusXM

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GBL

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$29.63

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LSXMA

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WETF

WisdomTree

$9.98

-0.11 (-1.09%)

16:13
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WisdomTree to close, liquidate three ETFs »

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CONN

Conn's

$17.10

0.15 (0.88%)

16:11
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WMT

Wal-Mart

$74.87

-0.655 (-0.87%)

, WFM

Whole Foods

$42.95

-0.255 (-0.59%)

16:11
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Periodicals
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WMT

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WFM

Whole Foods

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AMZN

Amazon.com

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APDN

Applied DNA Sciences

$1.09

0.06 (5.83%)

16:10
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Applied DNA Sciences receives order to tag 27.5M pounds of cotton »

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MOCO

Mocon

16:08
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06/23
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16:08
Hot Stocks
Gabelli liquidates stake in Mocon »

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TKTDY

Takata

$3.15

1.2199 (63.21%)

16:03
06/23/17
06/23
16:03
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16:03
Periodicals
Takata to seek bankruptcy protection as soon as Sunday, WSJ reports »

Takata intends to seek…

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TIPT

Tiptree Financial

16:02
06/23/17
06/23
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16:02
Hot Stocks
Tiptree Financial repurchases 1M shares from Nomura Securities »

Tiptree has repurchased…

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PFBC

Preferred Bank

16:01
06/23/17
06/23
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16:01
Hot Stocks
Preferred Bank raises quarterly dividend 11% to 20c per share »

Preferred Bank reported…

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AMGN

Amgen

16:01
06/23/17
06/23
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16:01
Hot Stocks
Amgen receives positive CHMP opinion to expand use of Mimpara »

Amgen announced that the…

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