Breaking News Instant updates and real-time market news.

FOLD

Amicus

$7.74

0.17 (2.25%)

07:33
05/19/17
05/19
07:33
05/19/17
07:33

Amicus announces planned analysis of ESSENCE trial primary endpoints

Amicus Therapeutics announced it has completed the analysis plan for the primary endpoints in the blinded ongoing Phase 3 clinical study, ESSENCE, of the novel topical medicine SD-101 for epidermolysis bullosa. ESSENCE is a double-blind, placebo-controlled registration study that completed enrollment of more than 160 patients who have a documented diagnosis of Simplex, Recessive Dystrophic, or Junctional non-Herlitz EB. Based on discussions and written communication from the Dermatology Division of the U.S. FDA, Amicus will analyze the primary endpoints for the Phase 3 ESSENCE study as follows: The endpoint of "time to wound closure within 3 months" will be analyzed first. If the difference between SD-101 6% and placebo is statistically significant, then the study will be considered a success; If the first endpoint is statistically significant, then "proportion of patients with target wound closure at month 3" will be analyzed and considered statistically significant at p less than or equal to 0.05. Amicus said it is on track to report top-line data from the ESSENCE study during the third quarter of 2017. To date, more than 95% of patients completing the 3-month primary treatment period have elected to continue in the open-label extension study. Jay Barth, Chief Medical Officer of Amicus, said, "We believe that the planned analysis of the primary endpoints increases our overall likelihood for success in the Phase 3 ESSENCE study of SD-101 for epidermolysis bullosa."

  • 13

    Jun

FOLD Amicus
$7.74

0.17 (2.25%)

11/29/16
COWN
11/29/16
NO CHANGE
Target $12
COWN
Outperform
Amicus price target lowered to $12 from $15 at Cowen
Cowen analyst Ritu Baral lowered her price target on Amicus to $12 from $15 after the FDA told the company it could not file the Galafold NDA with current data and that data from a new trial is expected in 2019. Baral maintained her Outperform rating on Amicus, stating that the planned GI trial has a good chance of success.
01/24/17
BARD
01/24/17
UPGRADE
BARD
Outperform
Amicus upgraded to Outperform from Neutral at Baird
01/24/17
BARD
01/24/17
UPGRADE
Target $10
BARD
Outperform
Amicus upgraded to Outperform at Baird
As reported previously, Baird analyst Michael Ulz upgraded Amicus to Outperform from Neutral saying the company removed two overhangs by providing regulatory clarity for Galafold in the U.S. as well as a strengthening its balance sheet. The analyst believes the launch of Galafold by itself supports the company's current valuation and he sees multiple opportunities for upside from its pipeline. Ulz raised his price target to $10 from $7 on Amicus shares.
01/24/17
01/24/17
UPGRADE

On The Fly: Top five analyst upgrades
Catch up on today's top five analyst upgrades with this list compiled by The Fly: 1. Tableau (DATA) upgraded to Buy from Neutral at Citi with analyst Walter Pritchard saying consensus estimates for fiscal 2017 look low. Revenue transition impacted numbers more than the Street realized in 2016, Pritchard tells investors in a research note. The analyst raised his price target for the shares to $64 from $50. 2. Agrium (AGU) upgraded to Outperform from Market Perform at Cowen, while CF Industries (CF), Mosaic (MOS), and Potash (POT) were upgraded to Market Perform from Underperform. 3. Calithera Biosciences (CALA) upgraded to Neutral from Sell at Citi with analyst Robyn Karnauskas citing her conversation with management. Management now appears more open to partnering, Karnauskas tells investors in a research note. 4. Home Bancshares (HOMB) upgraded to Buy from Hold at Sandler O'Neill. 5. Amicus (FOLD) upgraded to Outperform from Neutral at Baird with analyst Michael Ulz saying the company removed two overhangs by providing regulatory clarity for Galafold in the U.S. as well as a strengthening its balance sheet. Ulz raised his price target to $10 from $7 on Amicus shares. This list is just a portion of The Fly's full analyst coverage. To see The Fly's full Street Research coverage, click here.

TODAY'S FREE FLY STORIES

TOO

Teekay Offshore Partners

$2.55

-0.03 (-1.16%)

20:27
07/27/17
07/27
20:27
07/27/17
20:27
Downgrade
Teekay Offshore Partners rating change at Raymond James »

Teekay Offshore…

03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

QEP

QEP Resources

$7.93

-1.34 (-14.46%)

20:26
07/27/17
07/27
20:26
07/27/17
20:26
Downgrade
QEP Resources rating change at JPMorgan »

QEP Resources downgraded…

03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

  • 27

    Jul

  • 14

    Aug

RDFN

Redfin

20:26
07/27/17
07/27
20:26
07/27/17
20:26
Syndicate
Redfin 9.231M share IPO priced at $15.00 »

The deal range is…

03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

  • 27

    Jul

  • 28

    Jul

XOM

Exxon Mobil

$80.83

0.46 (0.57%)

, CVX

Chevron

$106.11

0.99 (0.94%)

20:25
07/27/17
07/27
20:25
07/27/17
20:25
Earnings
Notable companies reporting before tomorrow's open »

Notable companies…

XOM

Exxon Mobil

$80.83

0.46 (0.57%)

CVX

Chevron

$106.11

0.99 (0.94%)

MRK

Merck

$63.69

1.89 (3.06%)

ABBV

AbbVie

$71.73

-0.86 (-1.18%)

AAL

American Airlines

$50.00

-1.01 (-1.98%)

COL

Rockwell Collins

$109.02

-0.53 (-0.48%)

03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

  • 28

    Jul

  • 28

    Jul

  • 28

    Jul

  • 28

    Jul

  • 28

    Jul

  • 28

    Jul

  • 07

    Aug

  • 28

    Aug

  • 22

    Sep

TTPH

Tetraphase

$6.96

-0.92 (-11.68%)

20:22
07/27/17
07/27
20:22
07/27/17
20:22
Syndicate
Tetraphase 10M share Secondary priced at $6.50 »

Piper Jaffray, BMO…

03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

  • 28

    Jul

BVN

Buenaventura

$12.45

0.1 (0.81%)

19:26
07/27/17
07/27
19:26
07/27/17
19:26
Earnings
Buenaventura reports Q2 EPS (2c), may not compare to consensus 26c »

Reports Q2 revenue…

03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

BAS

Basic Energy

$28.67

0.06 (0.21%)

19:02
07/27/17
07/27
19:02
07/27/17
19:02
Hot Stocks
Breaking Hot Stocks news story on Basic Energy »

Basic Energy backs FY17…

03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

  • 28

    Jul

  • 14

    Aug

BAS

Basic Energy

$28.67

0.06 (0.21%)

19:01
07/27/17
07/27
19:01
07/27/17
19:01
Earnings
Basic Energy reports Q2 adjusted EPS (57c), consensus (55c) »

Reports Q2 revenue…

03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

  • 28

    Jul

  • 14

    Aug

GE

General Electric

$25.79

0.2 (0.78%)

18:55
07/27/17
07/27
18:55
07/27/17
18:55
Periodicals
Breaking Periodicals news story on General Electric »

Uber CEO shortlists…

03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

  • 02

    Oct

AIV

Aimco

$44.01

0.13 (0.30%)

18:53
07/27/17
07/27
18:53
07/27/17
18:53
Earnings
Aimco reports Q2 AFFO 51c vs 50c last year »

Reports Q1 revenue…

03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

  • 28

    Jul

NOV

National Oilwell

$33.71

0.37 (1.11%)

18:43
07/27/17
07/27
18:43
07/27/17
18:43
Earnings
National Oilwell reports Q2 adjusted EPS (14c), consensus (15c) »

Reports Q2 revenue…

03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

  • 28

    Jul

  • 29

    Aug

AIG

AIG

$65.17

-0.02 (-0.03%)

, IEP

Icahn Enterprises

$53.12

-0.78 (-1.45%)

18:39
07/27/17
07/27
18:39
07/27/17
18:39
Periodicals
Senators worried over whether Icahn is pushing regulators on AIG, Reuters says »

U.S. Democratic Senators…

AIG

AIG

$65.17

-0.02 (-0.03%)

IEP

Icahn Enterprises

$53.12

-0.78 (-1.45%)

PRU

Prudential

$112.74

0.55 (0.49%)

03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

  • 03

    Aug

  • 03

    Aug

  • 27

    Sep

HTBK

Heritage Commerce

$13.85

-0.14 (-1.00%)

18:24
07/27/17
07/27
18:24
07/27/17
18:24
Earnings
Heritage Commerce reports Q2 EPS 19c, consensus 19c »

Reports Q2 NII $24.9M,…

03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

  • 01

    Aug

EGO

Eldorado Gold

$2.40

-0.07 (-2.83%)

18:22
07/27/17
07/27
18:22
07/27/17
18:22
Hot Stocks
Eldorado Gold cuts FY17 gold production view to 290K-340K ounces from 365K-400K »

In 2017 Eldorado expects…

03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

  • 28

    Jul

EGO

Eldorado Gold

$2.40

-0.07 (-2.83%)

18:21
07/27/17
07/27
18:21
07/27/17
18:21
Earnings
Eldorado Gold reports Q2 EPS 2c, consensus 1c »

Reports Q2 revenue…

03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

  • 28

    Jul

KVHI

KVH Industries

$11.25

1.05 (10.29%)

18:19
07/27/17
07/27
18:19
07/27/17
18:19
Hot Stocks
Breaking Hot Stocks news story on KVH Industries »

Vintage Capital reports…

03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

CASH

Meta Financial

$92.25

-1.4 (-1.49%)

18:18
07/27/17
07/27
18:18
07/27/17
18:18
Hot Stocks
Meta Financial agreement with H&R Block not renewed in 2018 »

Meta Financial Group and…

03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

  • 01

    Aug

SCG

Scana

$65.64

0.36 (0.55%)

, TOSBF

Toshiba, also use TOSYY

$2.41

-0.092 (-3.68%)

18:15
07/27/17
07/27
18:15
07/27/17
18:15
Hot Stocks
Scana and Santee Cooper to receive $2.168B in guaranty payments from Toshiba »

Scana's (SCG)…

SCG

Scana

$65.64

0.36 (0.55%)

TOSBF

Toshiba, also use TOSYY

$2.41

-0.092 (-3.68%)

TOSYY

Toshiba, also use TOSBF

$14.49

-0.41 (-2.75%)

03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

ATEN

A10 Networks

$6.31

-0.06 (-0.94%)

18:14
07/27/17
07/27
18:14
07/27/17
18:14
Earnings
A10 Networks sees Q3 adjusted EPS (9c)-(2c), consensus (2c) »

Sees Q3 revenue…

03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

  • 27

    Jul

  • 08

    Aug

NBLX

Noble Midstream

$45.35

0.15 (0.33%)

18:07
07/27/17
07/27
18:07
07/27/17
18:07
Hot Stocks
Noble Midstream increases dividend 8.5% to 44.6c per share »

Noble Midstream Partners…

03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

  • 03

    Aug

AMZN

Amazon.com

$1,046.00

-6.8 (-0.65%)

18:02
07/27/17
07/27
18:02
07/27/17
18:02
Hot Stocks
Amazon cosiders differnt sizes in physical retail »

Says hasn't yet…

03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

  • 27

    Jul

  • 16

    Aug

  • 18

    Aug

SAM

Boston Beer

$135.65

1.7 (1.27%)

, PFG

Principal Financial

$66.63

-0.03 (-0.05%)

18:00
07/27/17
07/27
18:00
07/27/17
18:00
Hot Stocks
On The Fly: After Hours Movers »

UP AFTER EARNINGS: Boston…

SAM

Boston Beer

$135.65

1.7 (1.27%)

PFG

Principal Financial

$66.63

-0.03 (-0.05%)

FSLR

First Solar

$44.81

-0.63 (-1.39%)

GIMO

Gigamon

$37.75

-1.5 (-3.82%)

BIDU

Baidu

$201.00

-0.17 (-0.08%)

UCTT

Ultra Clean

$24.54

-0.3 (-1.21%)

CY

Cypress Semiconductor

$14.64

-0.12 (-0.81%)

ALGN

Align Technology

$157.26

-1.43 (-0.90%)

EXPE

Expedia

$154.25

-2.69 (-1.71%)

CERN

Cerner

$63.52

-1.1 (-1.70%)

AGRX

Agile Therapeutics

$4.60

-0.17 (-3.56%)

ELLI

Ellie Mae

$109.90

-3.49 (-3.08%)

CCMP

Cabot Microelectronics

$73.62

-7.32 (-9.04%)

NUVA

NuVasive

$76.90

-2.56 (-3.22%)

WIX

Wix.com

$73.60

-3.25 (-4.23%)

FLS

Flowserve

$46.36

-0.28 (-0.60%)

ECHO

Echo Global

$17.35

-0.5 (-2.80%)

FLEX

Flex

$17.09

0.11 (0.65%)

PDFS

PDF Solutions

$18.67

-1.02 (-5.18%)

BOJA

Bojangles

$15.65

-0.25 (-1.57%)

LEG

Leggett & Platt

$51.79

-0.04 (-0.08%)

SBUX

Starbucks

$59.50

1.56 (2.69%)

MAT

Mattel

$21.30

0.38 (1.82%)

EA

Electronic Arts

$117.60

-0.4 (-0.34%)

AMZN

Amazon.com

$1,046.00

-6.8 (-0.65%)

WDC

Western Digital

$91.90

-1.06 (-1.14%)

INTC

Intel

$34.97

0.22 (0.63%)

03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

  • 27

    Jul

  • 27

    Jul

  • 27

    Jul

  • 27

    Jul

  • 27

    Jul

  • 27

    Jul

  • 27

    Jul

  • 27

    Jul

  • 27

    Jul

  • 27

    Jul

  • 27

    Jul

  • 27

    Jul

  • 27

    Jul

  • 27

    Jul

  • 27

    Jul

  • 27

    Jul

  • 27

    Jul

  • 27

    Jul

  • 27

    Jul

  • 27

    Jul

  • 27

    Jul

  • 28

    Jul

  • 28

    Jul

  • 28

    Jul

  • 28

    Jul

  • 03

    Aug

  • 07

    Aug

  • 08

    Aug

  • 08

    Aug

  • 09

    Aug

  • 10

    Aug

  • 10

    Aug

  • 14

    Aug

  • 15

    Aug

  • 15

    Aug

  • 16

    Aug

  • 16

    Aug

  • 18

    Aug

  • 21

    Aug

  • 23

    Aug

  • 28

    Aug

  • 29

    Aug

  • 04

    Sep

  • 06

    Sep

  • 07

    Sep

AMZN

Amazon.com

$1,046.00

-6.8 (-0.65%)

18:00
07/27/17
07/27
18:00
07/27/17
18:00
Hot Stocks
Amazon says becoming more efficient on optimizing new fulfillment centers »

continues to take up to…

03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

  • 27

    Jul

  • 16

    Aug

  • 18

    Aug

AMGN

Amgen

$172.15

-3.74 (-2.13%)

18:00
07/27/17
07/27
18:00
07/27/17
18:00
Hot Stocks
Amgen says FDA grants priority review for sBLA for Repatha »

Amgen announced that the…

03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

  • 14

    Aug

  • 14

    Sep

  • 03

    Feb

  • 17

    May

WDC

Western Digital

$91.98

-0.99 (-1.06%)

17:57
07/27/17
07/27
17:57
07/27/17
17:57
Earnings
Breaking Earnings news story on Western Digital »

Western Digital targeting…

03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

  • 27

    Jul

Get Full Fly Access

Breaking market intelligence sent straight to you
Our team of experts analyze every news story and filter out the noise to deliver real-time market moving news.
Up-to-date information on important industry events
Get real-time updates on events that are moving the market—from conferences and calls to syndicate announcements.
News focused on the companies in your portfolio
Create up to 12 portfolios with 150 stocks each, and see how active they are in market news.