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AZN

AstraZeneca

$34.17

-0.65 (-1.87%)

07:08
06/12/17
06/12
07:08
06/12/17
07:08

AstraZeneca says new data 'underpins' safety of Farxiga

AstraZeneca presented new data at the American Diabetes Association's Scientific Sessions underpinning the safety profile of Farxiga with an analysis of data pooled from dapagliflozin clinical trials, as well as three new cardiovascular outcomes analyses from the ongoing CVD-REAL study, the first large real-world evidence study of its kind evaluating treatment with SGLT-2 inhibitors, including dapagliflozin. In an updated safety analysis, data pooled from 30 Phase IIb/III clinical trials for dapagliflozin showed no new safety signals and the incidence of adverse events was generally similar to that in the control groups. Importantly, there was no imbalance in lower-limb amputations, with eight patients and seven patients identified in the dapagliflozin and control groups, respectively. Elisabeth Bjork, VP, Head of Cardiovascular and Metabolic Diseases, Global Medicines Development, said: "SGLT-2 inhibitors are being prescribed with greater frequency for patients with type-2 diabetes, so it is vital that we have a clear understanding of the safety profile of these medicines and examine their effectiveness in a real-world setting. The data we are presenting at ADA underpins the safety of Farxiga and highlights the potential for earlier use of the SGLT-2 inhibitor class, and in broader patient populations than originally understood."

  • 26

    Jun

AZN AstraZeneca
$34.17

-0.65 (-1.87%)

06/06/17
WELS
06/06/17
NO CHANGE
WELS
Amazon may be the next threat to drug pricing, says Wells Fargo
After CNBC recently reported that Amazon (AMZN) is considering going into the prescription pharmacy business in the U.S., Wells Fargo surveyed nearly 2,900 U.S. adults and found that 54% of those polled said they would use or would probably use "Amazon Pharmacy." While the e-commerce giant has not confirmed its U.S. pharmacy interest, if it did enter the market analyst David Maris believes it could see fast adoption and "usher in a new age of price transparency." Maris also wonders if pharmacy "may be just the beginning" and if Amazon eyes the "even larger prize" of fully integrated digital healthcare. Publicly traded large-cap pharmaceuticals companies include AstraZeneca (AZN), Bristol-Myers (BMY), Eli Lilly (LLY), GlaxoSmithKline (GSK), Johnson & Johnson (JNJ), Merck (MRK), Novartis (NVS), Pfizer (PFE), Roche (RHHBY) and Sanofi (SNY). Publicly traded retail pharmacy operators include CVS Health (CVS), Walgreens (WBA), Fred's (FRED) and Rite Aid (RAD).
06/05/17
PIPR
06/05/17
NO CHANGE
PIPR
Piper views AstraZeneca, J&J as ASCO standouts
The standouts at ASCO over the weekend were the "compelling results" presented on Johnson & Johnson's (JNJ) Zytiga from the Latitude study in prostate cancer and AstraZeneca's (AZN) Lynparza in the OlympiAD trial in BRCA mutant breast cancer, Piper Jaffray analyst Richard Purkiss tells investors in a research note. In lung cancer, Merck's (MRK) updated data in KN021G "appears more promising" than Bristol-Myers' (BMY) updated data in CM012, the analyst adds. Purkiss believes, however, that relative to recent ASCOs, the data "so far in totality is underwhelming."
06/01/17
RHCO
06/01/17
NO CHANGE
RHCO
SunTrust sees $240/share takeout price for Tesaro
After the Wall Street Journal reported yesterday that Tesaro (TSRO) is exploring a sale, albeit with "modest" interest, SunTrust analyst Peter Lawson says his analysis suggests a $240 per share takeout price for the company. Tesaro closed yesterday up $5.88, or 4%, to $149.31. Acquisitions in the PARP inhibitor space are more likely to happen after Clovis Oncology's (CLVS) ARIEL 3 data at the end of June, as the readout will provide a more apples-to-apples comparison to Tesaro and AstraZeneca (AZN), Lawson tells investors in a research note. His "bull case" points to a $286 per share price for Tesaro and $92 per share price for Clovis. Lawson has Buy ratings on both names. JPMorgan's Cory Kasimov this morning said he likes the setup for Clovis shares into the late June data announcement.
05/17/17
JPMS
05/17/17
UPGRADE
Target $72
JPMS
Overweight
Clovis upgraded to Overweight from Neutral at JPMorgan
JPMorgan analyst Cory Kasimov upgraded Clovis Oncology (CLVS) to Overweight and raised his price target for the shares to $72 from $58. The stock closed yesterday up 2%, or $1.05, to $49.56. The shares are down 35% over the last two months for "no clear fundamental reason," Kasimov tells investors in a research note. The analyst is "increasingly comfortable" recommending Clovis ahead of its Phase 3 study evaluating Rubraca in maintenance ovarian cancer now that more PARP class data has emerged. He has not seen "convincing evidence" that there is a clear efficacy difference between Clovis' rucaparib, Tesaro's (TSRO) niraparib and AstraZeneca's (AZN) olaparib.

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FX Action: EUR-USD, USD-JPY and other major pairings are in sideways mode »

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DE

Deere

$145.25

6.02 (4.32%)

09:53
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TSLA

Tesla

$312.60

-5.21 (-1.64%)

08:08
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11/23
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Tesla CEO highlights 'record time' on Australian ion battery »

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  • 16

    Jan

TSLA

Tesla

$312.60

-5.21 (-1.64%)

08:07
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Tesla completes construction on largest lithium ion battery in Australia »

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  • 16

    Jan

GSK

GlaxoSmithKline

$35.06

0.25 (0.72%)

, INVA

Innoviva

$13.42

0.01 (0.07%)

07:56
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GSK, Innoviva submit data to FDA for expanded Trelegy Ellipta label »

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GSK

GlaxoSmithKline

$35.06

0.25 (0.72%)

INVA

Innoviva

$13.42

0.01 (0.07%)

03/08/13
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SVM

Silvercorp Metals

$2.51

-0.07 (-2.71%)

07:52
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07:52
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Silvercorp Metals to buy back up to 5% of shares »

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CEL

Cellcom Israel

$10.00

-0.1 (-0.99%)

07:49
11/23/17
11/23
07:49
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07:49
Hot Stocks
Cellcom Israel now second layer company according to Concentration Law »

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GASS

StealthGas

$4.07

0.36 (9.70%)

07:06
11/23/17
11/23
07:06
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Recommendations
StealthGas analyst commentary at Jefferies »

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CPRT

Copart

$41.01

4.31 (11.74%)

07:02
11/23/17
11/23
07:02
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07:02
Recommendations
Copart analyst commentary at Jefferies »

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  • 19

    Dec

DE

Deere

$145.25

6.02 (4.32%)

06:56
11/23/17
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06:56
Upgrade
Deere rating change at Deutsche Bank »

Deere upgraded to Buy…

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  • 28

    Nov

DE

Deere

$145.25

6.02 (4.32%)

06:55
11/23/17
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06:55
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06:55
Recommendations
Deere analyst commentary at Wells Fargo »

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  • 28

    Nov

06:40
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General news
FX Update: The dollar has remained on a weakening track »

FX Update: The dollar has…

SECO

Seeco Holding

$8.34

0.14 (1.71%)

04:55
11/23/17
11/23
04:55
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04:55
Conference/Events
Seeco Holding management to meet with Jefferies »

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  • 23

    Nov

04:55
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Conference/Events
Deutsche Bank to hold a conference »

Thailand SET Corporate…

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RBC Capital to hold field trip »

European Utilities Field…

BASFY

BASF

$27.39

-0.13 (-0.47%)

04:55
11/23/17
11/23
04:55
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04:55
Conference/Events
BASF management to meet with Evercore ISI »

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  • 23

    Nov

  • 24

    Nov

RBS

RBS

$7.30

-0.04 (-0.54%)

04:55
11/23/17
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04:55
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04:55
Conference/Events
RBS management to meet with Jefferies »

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  • 23

    Nov

  • 24

    Nov

04:25
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FX Action: USD-CAD punched out a 10-day low »

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02:35
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General news
FX Update: The dollar has remained on a downward path »

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L

Loews

$49.36

-0.02 (-0.04%)

, GE

General Electric

$18.15

0.32 (1.79%)

18:41
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18:41
Hot Stocks
Loews CEO James Tisch buys 3M shares of General Electric »

In a regulatory filing,…

L

Loews

$49.36

-0.02 (-0.04%)

GE

General Electric

$18.15

0.32 (1.79%)

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BRFS

BRF S.A.

$12.77

-0.16 (-1.24%)

18:06
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BRF S.A. names Jose Aurelio Drummond Jr. as CEO »

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SU

Suncor

$35.42

0.2 (0.57%)

18:02
11/22/17
11/22
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18:02
Hot Stocks
Suncor closes sale of equity interest in East Tan Farm, redeems $750M in debt »

Suncor successfully…

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  • 05

    Dec

SAP

SAP

$113.85

-1.44 (-1.25%)

17:53
11/22/17
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17:53
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17:53
Periodicals
SAP launches investigation of sales practices in Gulf region, Reuters reports »

SAP has launched a formal…

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