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JNJ

Johnson & Johnson

$131.82

0.29 (0.22%)

18:31
06/12/17
06/12
18:31
06/12/17
18:31

Janssen: Invokana significantly cuts risk of CV death, heart attack, stroke

Johnson & Johnson's Janssen announced that results from the landmark CANVAS Program showed INVOKANA significantly reduced the combined risk of cardiovascular death, myocardial infarction, and nonfatal stroke, versus placebo in patients with type 2 diabetes mellitus at risk for or with a history of CV disease. The results also showed canagliflozin treatment was associated with a reduced risk for hospitalization for heart failure and demonstrated potential renal protective effects. These data from the integrated analysis of the CANVAS and CANVAS-R trials were published in the New England Journal of Medicine, and presented at the American Diabetes Association annual meeting. Specifically, canagliflozin achieved a 14% reduction in the risk of the composite primary endpoint of CV mortality, nonfatal MI or nonfatal stroke, and demonstrated the CV safety of canagliflozin and superiority compared to placebo. Each component evenly contributed to this risk reduction, including nonfatal MI by 15%, CV death by 13%, and nonfatal stroke by 10%. These outcomes were broadly consistent across various patient subgroups and across the individual components of the primary endpoint. Additional analysis further revealed canagliflozin lowered the risk of HHF by 33% and provided sustained positive effects on glycemic and blood pressure control, as well as weight reduction, demonstrating wide-ranging durability. In addition, canagliflozin showed potential renal protective effects, delaying progression of albuminuria and reducing the risk of clinically important renal composite outcomes by 40%. Overall adverse events seen in the CANVAS Program were consistent with previous findings. An increased risk of amputation with canagliflozin was seen in both the completed CANVAS and CANVAS-R studies. There was an increased risk of amputation corresponding to a hazard ratio of 1.97. The highest absolute risk of amputation occurred in patients with a prior history of amputation or peripheral vascular disease, but the relative risk for amputation with canagliflozin was comparable across these subgroups. These findings have been shared by the U.S. FDA and will be reflected in the U.S. Prescribing Information for canagliflozin, the company noted. Separately, while an increased risk of adjudicated low trauma fracture was identified in the CANVAS study, no increase was observed in the CANVAS-R study. A full assessment is ongoing to provide a complete safety review of these results.

  • 13

    Jun

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    Jun

JNJ Johnson & Johnson
$131.82

0.29 (0.22%)

06/06/17
WELS
06/06/17
NO CHANGE
WELS
Amazon may be the next threat to drug pricing, says Wells Fargo
After CNBC recently reported that Amazon (AMZN) is considering going into the prescription pharmacy business in the U.S., Wells Fargo surveyed nearly 2,900 U.S. adults and found that 54% of those polled said they would use or would probably use "Amazon Pharmacy." While the e-commerce giant has not confirmed its U.S. pharmacy interest, if it did enter the market analyst David Maris believes it could see fast adoption and "usher in a new age of price transparency." Maris also wonders if pharmacy "may be just the beginning" and if Amazon eyes the "even larger prize" of fully integrated digital healthcare. Publicly traded large-cap pharmaceuticals companies include AstraZeneca (AZN), Bristol-Myers (BMY), Eli Lilly (LLY), GlaxoSmithKline (GSK), Johnson & Johnson (JNJ), Merck (MRK), Novartis (NVS), Pfizer (PFE), Roche (RHHBY) and Sanofi (SNY). Publicly traded retail pharmacy operators include CVS Health (CVS), Walgreens (WBA), Fred's (FRED) and Rite Aid (RAD).
06/07/17
FBCO
06/07/17
NO CHANGE
Target $38
FBCO
Outperform
ASCO meeting highlights pressure on Pfizer cancer assets, says Credit Suisse
Credit Suisse analyst Vamil Divan said he came away from the ASCO meeting feeling like positive progress by competitors is increasing the pressure on Pfizer's (PFE) cancer assets, specifically pointing to positive data for Roche's (RHHBY) Alecensa, Johnson & Johnson's (JNJ) Zytiga and Eli Lilly's (LLY) abemaciclib. Additionally, competition in the immune-oncology and PARP spaces will make it more challenging for Pfizer to gain traction, added Divan. He keeps an Outperform rating on Pfizer, citing valuation and its dividend yield, but he has concerns about its upcoming patent expirations and growth products.
06/09/17
FBCO
06/09/17
NO CHANGE
FBCO
Outperform
Tesaro prostate study suspension due to fast enrollment, says Credit Suisse
After speaking to Tesaro (TSRO), after they spoke to their partner Johnson & Johnson (JNJ), Credit Suisse analyst Alethia Young said the news of the companies' suspension of participant recruitment in the study of niraparib in prostate cancer is actually positive, since it is due to the trial enrolling faster than expected. The suspension has nothing to do with safety or efficacy and is not a clinical hold, but is due to having too many patients in the first part of trial, Young was told. She maintains an Outperform rating on Tesaro shares.
06/12/17
RHCO
06/12/17
NO CHANGE
RHCO
Misunderstanding creates buying opportunity in Tesaro stock, says SunTrust
SunTrust analyst Peter Lawson says that the suspension of participant recruitment by Johnson & Johnson (JNJ) for a study of Tesaro's (TSRO) PARP inhibitor Zejula in prostate cancer "is being incorrectly viewed as a clinical hold." After speaking with J&J, Lawson says that the suspension was not due to clinical or safety issues, but to overly fast enrollment. The analyst says that the early data on PARP inhibitors in prostate cancer has been "encouraging." He believes that the misunderstanding has created a buying opportunity in Tesaro stock. .

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DE

Deere

$123.98

-2.65 (-2.09%)

, EL

Estee Lauder

$98.32

-2.75 (-2.72%)

20:25
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Notable companies reporting before tomorrow's open »

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DE

Deere

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EL

Estee Lauder

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FL

Foot Locker

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HIBB

Hibbett Sports

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PCTY

Paylocity

$45.10

-1.06 (-2.30%)

, PAYX

Paychex

$54.98

-1.26 (-2.24%)

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Paylocity announces Michael Haske's promotion to president & COO »

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Paylocity

$45.10

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PAYX

Paychex

$54.98

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ADP

ADP

$104.68

-6.42 (-5.78%)

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SN

Sanchez Energy

$4.87

-0.145 (-2.89%)

18:04
08/17/17
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18:04
Hot Stocks
Sanchez Energy to sell Javelina asset in Eagle Ford shale for about $105M »

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BABA

Alibaba

$163.92

4.42 (2.77%)

17:50
08/17/17
08/17
17:50
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17:50
Recommendations
Alibaba analyst commentary at Baird »

Alibaba price target…

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ASYS

Amtech Systems

$10.14

-0.51 (-4.79%)

17:48
08/17/17
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17:48
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17:48
Syndicate
Amtech Systems announces common stock offering, no amount given »

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CPCAY

Cathay Pacific

$7.47

0.15 (2.05%)

17:47
08/17/17
08/17
17:47
08/17/17
17:47
Upgrade
Cathay Pacific rating change at Goldman Sachs »

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RTN

Raytheon

$177.25

-0.83 (-0.47%)

17:32
08/17/17
08/17
17:32
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17:32
Hot Stocks
Raytheon awarded $104.8M government contract »

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SPWH

Sportsman's Warehouse

$3.46

-0.12 (-3.35%)

, GLOB

Globant

$42.26

-0.64 (-1.49%)

17:32
08/17/17
08/17
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17:32
Hot Stocks
On The Fly: After Hours Movers »

UP AFTER EARNINGS:…

SPWH

Sportsman's Warehouse

$3.46

-0.12 (-3.35%)

GLOB

Globant

$42.26

-0.64 (-1.49%)

ROST

Ross Stores

$53.33

-1.04 (-1.91%)

GPS

Gap

$22.68

0.11 (0.49%)

AMAT

Applied Materials

$43.12

-1.34 (-3.01%)

FLDM

Fluidigm

$3.60

-0.04 (-1.10%)

SENS

Senseonics

$2.44

0.02 (0.83%)

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LMT

Lockheed Martin

$301.42

-4.38 (-1.43%)

17:32
08/17/17
08/17
17:32
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17:32
Hot Stocks
Lockheed Martin, others awarded $499M government contract »

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  • 23

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CTRL

Control4

$22.27

-0.9 (-3.88%)

, AMRI

Albany Molecular

$21.74

-0.01 (-0.05%)

17:21
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08/17
17:21
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Hot Stocks
Control4 to replace Albany Molecular in S&P 600 at open on 8/22 »

The Carlyle Group (CG)…

CTRL

Control4

$22.27

-0.9 (-3.88%)

AMRI

Albany Molecular

$21.74

-0.01 (-0.05%)

CG

Carlyle Group

$21.20

-0.2 (-0.93%)

03/08/13
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CI

Cigna

$178.03

-1.83 (-1.02%)

17:15
08/17/17
08/17
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17:15
Hot Stocks
Cigna's Bacus sells 2,236 common shares »

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  • 06

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17:09
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17:09
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General news
Sen. Corker: Trump has not demonstrated competence to be president »

According to various…

BTU

Peabody Energy

$27.94

-0.27 (-0.96%)

17:07
08/17/17
08/17
17:07
08/17/17
17:07
Syndicate
Peabody Energy files to sell 12.8M shares of common stock for holders »

Peabody Energy announced…

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CEMI

Chembio Diagnostics

$6.05

-0.1 (-1.63%)

17:02
08/17/17
08/17
17:02
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17:02
Hot Stocks
Chembio Diagnostics CFO Richard Larkin to retire »

Chembio Diagnostics…

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CRMT

America's Car-Mart

$36.90

-0.65 (-1.73%)

17:01
08/17/17
08/17
17:01
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17:01
Earnings
America's Car-Mart reports Q1 EPS 90c, consensus 91c »

Reports Q1 revenue $146M,…

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GM

General Motors

$35.00

-0.75 (-2.10%)

16:59
08/17/17
08/17
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16:59
Hot Stocks
General Motors' Jacoby sells 20,000 common shares »

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CBI

CB&I

$9.78

-0.19 (-1.91%)

, FLR

Fluor

$37.77

-0.67 (-1.74%)

16:59
08/17/17
08/17
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16:59
Hot Stocks
President Donald Trump shelves plans to create infrastructure advisory council »

According to various…

CBI

CB&I

$9.78

-0.19 (-1.91%)

FLR

Fluor

$37.77

-0.67 (-1.74%)

ACM

Aecom

$31.09

-0.43 (-1.36%)

MTZ

MasTec

$39.20

0.45 (1.16%)

CCI

Crown Castle

$104.14

0.35 (0.34%)

JEC

Jacobs Engineering

$50.25

-0.8 (-1.57%)

MLM

Martin Marietta

$200.41

-4.7 (-2.29%)

USCR

U.S. Concrete

$77.20

-0.9 (-1.15%)

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  • 11

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CQP

Cheniere Energy Partners

$28.08

-0.08 (-0.28%)

16:53
08/17/17
08/17
16:53
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16:53
Syndicate
Breaking Syndicate news story on Cheniere Energy Partners »

Cheniere Energy Partners…

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DDS

Dillard's

$54.83

-1.1 (-1.97%)

16:50
08/17/17
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Hot Stocks
Dillard's raises quarterly dividend to 10c from 7c per share »

The dividend is payable…

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ABTL

Autobytel

$8.30

-0.12 (-1.43%)

16:46
08/17/17
08/17
16:46
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16:46
Hot Stocks
Autobytel announces purchases under stock repurchase authorization »

Autobytel announced that…

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GBL

GAMCO Investors

$29.41

-0.4 (-1.34%)

, CMT

Core Molding

$21.07

-0.36 (-1.68%)

16:43
08/17/17
08/17
16:43
08/17/17
16:43
Hot Stocks
Breaking Hot Stocks news story on GAMCO Investors, Core Molding »

Gabelli reports 10.94%…

GBL

GAMCO Investors

$29.41

-0.4 (-1.34%)

CMT

Core Molding

$21.07

-0.36 (-1.68%)

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  • 06

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GUID

Guidance Software

16:41
08/17/17
08/17
16:41
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16:41
Hot Stocks
Breaking Hot Stocks news story on Guidance Software »

Soros Fund Management…

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GBL

GAMCO Investors

$29.41

-0.4 (-1.34%)

, MTRN

Materion

$37.00

-1.1 (-2.89%)

16:41
08/17/17
08/17
16:41
08/17/17
16:41
Hot Stocks
Breaking Hot Stocks news story on GAMCO Investors, Materion »

Gabelli reports 6.66%…

GBL

GAMCO Investors

$29.41

-0.4 (-1.34%)

MTRN

Materion

$37.00

-1.1 (-2.89%)

03/08/13
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FALC

FalconStor

$0.19

-0.004 (-2.12%)

16:41
08/17/17
08/17
16:41
08/17/17
16:41
Hot Stocks
FalconStor announces Todd Brooks as CEO and Patrick McClain as CFO »

FalconStor announced the…

03/08/13
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16:36
08/17/17
08/17
16:36
08/17/17
16:36
General news
Fed Balance Sheet Level data reported »

Week of 8/16 Fed Balance…

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