Breaking News Instant updates and real-time market news.

NVCR

Novocure

, CELG

Celgene

$137.74

1.43 (1.05%)

07:23
07/24/17
07/24
07:23
07/24/17
07:23

Novocure announces Phase 1b trial of marizomib, temozolomid, Optune combination

Novocure (NVCR) announced a new arm for a phase 1b study to evaluate the safety of marizomib and temozolomide in combination with Optune, Novocure's Tumor Treating Fields delivery system, as adjuvant treatment for patients with newly diagnosed glioblastoma following radiation therapy with concurrent temozolomide. The trial is the first to study Optune in combination with an investigational drug. Marizomib is a novel, brain-penetrant proteasome inhibitor developed by Triphase Accelerator Corporation and acquired by Celgene Corporation (CELG). Celgene is responsible for marizomib's development. Celgene and Triphase modified their current phase 1b multicenter, open-label study of marizomib in combination with temozolomide and radiotherapy in patients with grade IV malignant gliomas to include Optune. A cohort of 12 GBM patients will be treated with Optune in combination with marizomib and temozolomide after initial treatment with radiation and temozolomide has been completed. The primary objective for the Optune portion of the study is to determine the safety of the combination of marizomib and temozolomide with the addition of Optune in patients entering the adjuvant treatment phase. Secondary objectives for the Optune portion of the study include assessing preliminary clinical activity of the combination of Optune, marizomib and temozolomide in patients entering adjuvant therapy, progression-free survival and overall survival. The protocol has been submitted to an institutional review board, and this arm of the trial is expected to open in the third quarter of 2017.

NVCR

Novocure

CELG

Celgene

$137.74

1.43 (1.05%)

  • 27

    Jul

  • 27

    Jul

  • 31

    Jul

  • 30

    Aug

  • 11

    Sep

NVCR Novocure

07/12/17
WEDB
07/12/17
NO CHANGE
WEDB
Novocure removed from Best Ideas List at Wedbush
Wedbush removed Novocure from its Best Ideas List based on valuation.
05/24/17
WELS
05/24/17
UPGRADE
Target $15
WELS
Outperform
Novocure upgraded to Outperform from Market Perform at Wells Fargo
Wells Fargo analyst Larry Biegelsen upgraded Novocure to Outperform and raised his price target for the shares to $15 from $11.50. Feedback from consultants suggest that physician impression of Optune may be improving, Biegelsen tells investors in a research note. The consultants believe that the 5-year safety/efficacy results from EF-14 trial, which showed continued survival benefit, is "meaningful and would be hard to ignore," even for doctors previously skeptical of Optune for treating glioblastoma, the analyst adds.
04/06/17
WEDB
04/06/17
NO CHANGE
Target $20
WEDB
Outperform
Wedbush has more confidence in Novocure after meetings, data
After hosting meetings with Novocure management and reviewing presentations at the American Association of Cancer Research conference, Wedbush analyst Tao Levy said he has greater confidence that its Optune System is one of the more exciting, but underappreciated, technology platforms in the space. He keeps an Outperform rating and $20 price target on Novocure shares, which are also on the Wedbush Best Ideas List.
01/11/17
WELS
01/11/17
DOWNGRADE
WELS
Market Perform
Novocure downgraded to Market Perform from Outperform at Wells Fargo
Wells Fargo analyst Larry Biegelsen downgraded Novocure to Market Perform saying the company's U.S. prescription volume in 2016 has been "flatter" than expected. Consultant feedback suggests that Optune adoption in the U.S. should continue to improve but is unlikely to significantly accelerate, Biegelsen tells investors in a research note following Novocure's preliminary Q4 results. The analyst lowered his price target range for the shares to $8-$9 from $12-$14.
CELG Celgene
$137.74

1.43 (1.05%)

07/11/17
JEFF
07/11/17
NO CHANGE
JEFF
Jefferies fundamentally positive on Biotechnology, lists top picks
Jefferies analyst Michael Yee rolled out coverage of 12 Biotechnology names in a 550 page research report. The analyst is "fundamentally positive" on the sector, believing investor interest in large-caps will pick up "as the road to repair slowly continues." He believes the smid-cap space is "becoming a good stock-pickers' market." Yee's top picks in Biotech space include Celgene (CELG), Vertex (VRTX), Spark Therapeutics (ONCE), Prothena (PRTA) and Intercept (ICPT). The analyst's best picks in the smid-cap space are Spark, Prothena, Intercept and FibroGen (FGEN).
07/10/17
JEFF
07/10/17
INITIATION
Target $160
JEFF
Buy
Celgene assumed with a Buy at Jefferies
Jefferies assumed coverage on Celgene with a Buy and a $160 price target.
07/10/17
BOFA
07/10/17
NO CHANGE
Target $153
BOFA
Buy
Celgene could be worth $200 per share, says BofA/Merrill
BofA/Merrill analyst Ying Huang said in an upside bull case scenario, Celgene could be worth $200 per share based on luspatercept expectations, with Phase 3 studies anticipated in mid-2018. Huang assumes a 77% probability of FDA approval, 25-30% peak penetration, a $78K annual cost, and estimates peak sales of $1.8B in MDS and beta-nhalassemia. The analyst rates Celgene a Buy with a $153 price target.
07/06/17
FBCO
07/06/17
NO CHANGE
Target $148
FBCO
Outperform
Celgene should keep building on 'solid' tumor franchise, says Credit Suisse
Credit Suisse analyst Alethia Young notes that Celgene (CELG) announced a global collaboration with BeiGene (BGNE) on BGBA317 which is ITS PD-1. The analyst believes that adding a PD-1 in solid tumors makes "good sense" as she had hoped that it would broaden out its platform in solid tumors. Young reiterates an Outperform rating and $148 price target on Celgene's shares.

TODAY'S FREE FLY STORIES

NFLX

Netflix

$190.12

0.56 (0.30%)

, DIS

Disney

$111.27

0.7 (0.63%)

20:03
12/17/17
12/17
20:03
12/17/17
20:03
Hot Stocks
On The Fly: Top five weekend stock stories »

Catch up on the…

NFLX

Netflix

$190.12

0.56 (0.30%)

DIS

Disney

$111.27

0.7 (0.63%)

FOXA

21st Century Fox

$34.99

0.11 (0.32%)

FOX

21st Century Fox

MSGN

MSG Networks

$19.80

0.05 (0.25%)

AMCX

AMC Networks

$55.33

1.16 (2.14%)

VIAB

Viacom

$30.24

0.53 (1.78%)

VIA

Viacom

$34.40

0.25 (0.73%)

XOM

Exxon Mobil

$83.03

0.13 (0.16%)

ONCE

Spark Therapeutics

$46.37

1.16 (2.57%)

ALK

Alaska Air

$70.83

1.44 (2.08%)

ORCL

Oracle

$48.30

-1.89 (-3.77%)

HUM

Humana

$253.64

3.03 (1.21%)

KND

Kindred Healthcare

$8.60

0.45 (5.52%)

03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

  • 12

    Jan

  • 08

    Feb

  • 08

    Feb

CME

CME Group

$151.07

0.65 (0.43%)

19:31
12/17/17
12/17
19:31
12/17/17
19:31
Periodicals
CME becomes second exchange to launch bitcoin futures, Reuters says »

CME Group became the…

03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

SPPI

Spectrum

$19.04

0.38 (2.04%)

19:10
12/17/17
12/17
19:10
12/17/17
19:10
Hot Stocks
Spectrum Pharmaceuticals terminates Rajesh Shrotriya from CEO position »

Spectrum Pharmaceuticals…

03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

SO

Southern Company

$51.31

-0.21 (-0.41%)

18:58
12/17/17
12/17
18:58
12/17/17
18:58
Hot Stocks
Georgia Power expects power to be restored by midnight tonight »

Georgia Power continues…

03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

BHP

BHP Billiton

$43.08

0.74 (1.75%)

, XOM

Exxon Mobil

$83.03

0.13 (0.16%)

18:29
12/17/17
12/17
18:29
12/17/17
18:29
Periodicals
BHP, Esso to separately market Gippsland Basin gas, Reuters says »

The Australian…

BHP

BHP Billiton

$43.08

0.74 (1.75%)

XOM

Exxon Mobil

$83.03

0.13 (0.16%)

03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

BDRBF

Bombardier

17:48
12/17/17
12/17
17:48
12/17/17
17:48
Hot Stocks
Bombardier wins contract to provide Melbourne high-capacity signaling system »

Bombardier…

03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

TWX

Time Warner

$90.25

0.6 (0.67%)

, CMCSA

Comcast

$39.71

0.59 (1.51%)

17:38
12/17/17
12/17
17:38
12/17/17
17:38
Hot Stocks
Box Office Battle: 'Star Wars: The Last Jedi'' opens to $220M in U.S. »

Disney (DIS) and…

TWX

Time Warner

$90.25

0.6 (0.67%)

CMCSA

Comcast

$39.71

0.59 (1.51%)

CMCSK

Comcast

SNE

Sony

$44.84

0.39 (0.88%)

FOX

21st Century Fox

FOXA

21st Century Fox

$34.99

0.11 (0.32%)

LGF.A

Lionsgate

$32.99

0.49 (1.51%)

DIS

Disney

$111.27

0.7 (0.63%)

VIAB

Viacom

$30.24

0.53 (1.78%)

VIA

Viacom

$34.40

0.25 (0.73%)

03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

  • 08

    Feb

  • 08

    Feb

EQIX

Equinix

$457.85

-2.5 (-0.54%)

17:17
12/17/17
12/17
17:17
12/17/17
17:17
Hot Stocks
Equinix announces acquisition of Metronode »

Equinix announced that it…

03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

MET

MetLife

$51.41

-1.08 (-2.06%)

17:11
12/17/17
12/17
17:11
12/17/17
17:11
Periodicals
Metlife failed to pay some pensions, Reuters reports »

Metlife failed to pay…

03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

  • 12

    Jun

GM

General Motors

$40.95

0.14 (0.34%)

17:06
12/17/17
12/17
17:06
12/17/17
17:06
Periodicals
GM facing $1B reckoning in ignition-switch settlement, WSJ reports »

General Motors faces a…

03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

  • 09

    Jan

  • 16

    Jan

TCEHY

Tencent

$50.31

-0.231 (-0.46%)

, BABA

Alibaba

$173.55

1.8 (1.05%)

16:58
12/17/17
12/17
16:58
12/17/17
16:58
Periodicals
Tencent to buy stake in supermarket chain, Bloomberg reports »

Tencent (TCEHY) to buy a…

TCEHY

Tencent

$50.31

-0.231 (-0.46%)

BABA

Alibaba

$173.55

1.8 (1.05%)

03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

AMZN

Amazon.com

$1,179.14

4.88 (0.42%)

16:50
12/17/17
12/17
16:50
12/17/17
16:50
Periodicals
Amazon in talks to acquire Sqrrl, Axios reports »

Amazon is said to be in…

03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

  • 18

    Mar

HUM

Humana

$253.64

3.03 (1.21%)

, KND

Kindred Healthcare

$8.60

0.45 (5.52%)

16:48
12/17/17
12/17
16:48
12/17/17
16:48
Periodicals
Humana in talks to acquire Kindred Healthcare, Reuters reports »

Humana (HUM) is in…

HUM

Humana

$253.64

3.03 (1.21%)

KND

Kindred Healthcare

$8.60

0.45 (5.52%)

03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

ORCL

Oracle

$48.30

-1.89 (-3.77%)

16:39
12/17/17
12/17
16:39
12/17/17
16:39
Hot Stocks
Oracle buys Aconex for $1.2B »

Oracle announced that it…

03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

CSX

CSX

$52.93

-4.38 (-7.64%)

16:35
12/17/17
12/17
16:35
12/17/17
16:35
Hot Stocks
CSX announces death of CEO E. Hunter Harrison »

CSX issued the following…

03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

VRX

Valeant

$19.71

0.03 (0.15%)

16:09
12/17/17
12/17
16:09
12/17/17
16:09
Hot Stocks
Valeant, subsidiary announce early tender results »

Valeant Pharmaceuticals…

03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

  • 27

    Dec

  • 18

    Jun

KMF

Kayne Anderson Midstream/Energy Fund

$13.78

0.09 (0.66%)

16:01
12/17/17
12/17
16:01
12/17/17
16:01
Hot Stocks
Kayne Anderson Midstream/Energy Fund announces distribution of 30c per share »

Kayne Anderson…

03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

KYN

Kayne Anderson MLP

15:59
12/17/17
12/17
15:59
12/17/17
15:59
Hot Stocks
Kayne Anderson MLP announces distribution of 45c per share for Q4 »

Kayne Anderson MLP…

03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

KED

Kayne Anderson Energy

$16.68

-0.01 (-0.06%)

15:56
12/17/17
12/17
15:56
12/17/17
15:56
Hot Stocks
Kayne Anderson Energy announces distribution 40c per share for Q4 »

Kayne Anderson Energy…

03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

KYE

Kayne Anderson Energy

$10.19

-0.01 (-0.10%)

15:53
12/17/17
12/17
15:53
12/17/17
15:53
Hot Stocks
Kayne Anderson Energy announces distribution of 25c per share for Q4 »

Kayne Anderson Energy…

03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

CSX

CSX

$52.93

-4.38 (-7.64%)

15:18
12/16/17
12/16
15:18
12/16/17
15:18
Hot Stocks
CSX announces death of CEO E. Hunter Harrison »

CSX issued the following…

03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

CBOE

CBOE Holdings

$126.37

0.31 (0.25%)

11:22
12/16/17
12/16
11:22
12/16/17
11:22
Periodicals
CBOE should not be treated as 'set and forget,' Barron's says »

Bitcoin futures have…

03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

DIS

Disney

$111.27

0.7 (0.63%)

, FOXA

21st Century Fox

$34.99

0.11 (0.32%)

11:17
12/16/17
12/16
11:17
12/16/17
11:17
Periodicals
Disney/Fox 'a murky web of deals within deals,' Barron's says »

Walt Disney's (DIS)…

DIS

Disney

$111.27

0.7 (0.63%)

FOXA

21st Century Fox

$34.99

0.11 (0.32%)

FOX

21st Century Fox

03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

ALK

Alaska Air

$70.83

1.44 (2.08%)

10:53
12/16/17
12/16
10:53
12/16/17
10:53
Periodicals
Alaska air should bounce back in 2018, Barron's says »

While shares of Alaska…

03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

ONCE

Spark Therapeutics

$46.37

1.16 (2.57%)

10:42
12/16/17
12/16
10:42
12/16/17
10:42
Periodicals
Spark Therapeutics selloff may be overdone, Barron's says »

Spark Therapeutics shares…

03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

  • 12

    Jan

Get Full Fly Access

Breaking market intelligence sent straight to you
Our team of experts analyze every news story and filter out the noise to deliver real-time market moving news.
Up-to-date information on important industry events
Get real-time updates on events that are moving the market—from conferences and calls to syndicate announcements.
News focused on the companies in your portfolio
Create up to 12 portfolios with 150 stocks each, and see how active they are in market news.