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NVAX

Novavax

$1.51

0.03 (2.03%)

16:14
07/24/17
07/24
16:14
07/24/17
16:14

Novavax: E205 increases magnitude, duration quality of RSV F immune response

Novavax announced positive topline data from its Phase 2 safety and immunogenicity trial of the RSV F Vaccine in older adults, new preclinical data on its RSV F Vaccine construct, additional findings from the prior Phase 2 and Phase 3 clinical trials in older adullts, and an operational update on the Phase 3 clinical trial of the RSV F Vaccine for infants via maternal immunization, known as Prepare. The Company anticipates initiating a Phase 2 efficacy trial in older adults in 2018. Topline data from the Phase 2 older adult safety and immunogenicity trial demonstrate the benefit of adjuvant formulations and two-dose regimens. The objective of the Phase 2 randomized, observer-blinded, placebo-controlled trial was to assess safety and immunogenicity of one and two-dose regimens of the RSV F Vaccine, with and without aluminum phosphate or Novavax' proprietary Matrix-M adjuvant, in 300 older adults. Participants were enrolled and vaccinated outside of the RSV season to best assess immunogenicity of the treatment arms. Immunogenicity outcomes indicate both aluminum phosphate and Matrix-M adjuvants significantly increased the magnitude, duration and quality of the immune response relative to a control of 135 microgram dose of the RSV F antigen alone. Similarly, two-dose regimens significantly increased immune responses and suggests two doses of the RSV F Vaccine with adjuvant may augment durability of the immune response to the vaccine. The data strongly support the inclusion of adjuvanted formulations of the RSV F Vaccine in future older adult trials. All formulations and regimens were safe and well-tolerated.

  • 24

    Jul

  • 26

    Sep

NVAX Novavax
$1.51

0.03 (2.03%)

12/16/16
CANT
12/16/16
INITIATION
Target $2
CANT
Neutral
Novavax initiated with a Neutral at Cantor
Cantor Fitzgerald analyst William Tanner started Novavax with a Neutral rating and $2 price target.
09/16/16
09/16/16
DOWNGRADE

On The Fly: Top five analyst downgrades
Catch up on today's top five analyst downgrades with this list compiled by The Fly: 1. 21st Century Fox (FOX, FOXA) downgraded to Market Perform from Outperform at Bernstein with analyst Jason Park citing a reduction in his estimates for the company's Star India business. 2. Wells Fargo (WFC) downgraded to Underweight from Neutral at Atlantic Equities. 3. Citi (C) downgraded to Neutral from Buy at Goldman with analyst Richard Ramsden saying Citi's expected earnings inflection has failed to materialize and ROEs are at 7.7%, well below management's 10% target. 4. McCormick (MKC) downgraded to Market Perform from Outperform at Bernstein with analyst Alexia Howard citing valuation. 5. Novavax (NVAX) downgraded to Neutral from Overweight at Piper Jaffray, to Neutral from Overweight at JPMorgan, to Neutral from Buy at Ladenburg, to Neutral from Outperform at Wedbush, and to Neutral from Buy at Citi. This list is just a portion of The Fly's full analyst coverage. To see The Fly's full Street Research coverage, click here.
09/16/16
SBSH
09/16/16
DOWNGRADE
Target $1.5
SBSH
Neutral
Novavax downgraded to Neutral from Buy at Citi
Citi analyst Joel Beatty downgraded Novavax to Neutral after the company's RSV vaccine for older adults failed in Phase 3. The analyst does not expect results from the one remaining clinical trial until 2019. He cut his price target for the shares to $1.50 from $12. Four other firms downgraded Novavax this morning.
09/16/16
WEDB
09/16/16
DOWNGRADE
Target $2
WEDB
Neutral
Novavax downgraded to Neutral from Outperform at Wedbush
Wedbush analyst Heather Behanna downgraded Novavax to Neutral and lowered its price target to $2 from $14 after the company's Phase III trial of RSV vaccine failed. This is the fourth downgrade of Novavax today.

TODAY'S FREE FLY STORIES

EXPR

Express

$11.01

0.135 (1.24%)

13:35
12/13/17
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  • 08

    Jan

DBD

Diebold

$17.78

-0.725 (-3.92%)

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CVG

Convergys

$24.12

0.15 (0.63%)

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  • 13

    Dec

$NSD

NASDAQ Market Internals

13:17
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Technical Analysis
NASDAQ market internals summary »

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$NYE

NYSE Market Internals

13:16
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DAL

Delta Air Lines

$53.48

-0.14 (-0.26%)

, EADSY

Airbus

$25.54

0.22 (0.87%)

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DAL

Delta Air Lines

$53.48

-0.14 (-0.26%)

EADSY

Airbus

$25.54

0.22 (0.87%)

BA

Boeing

$293.91

3.97 (1.37%)

03/08/13
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  • 14

    Dec

SBCF

Seacoast Banking

$25.52

0.21 (0.83%)

13:15
12/13/17
12/13
13:15
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Conference/Events
Seacoast Banking management to meet with SunTrust »

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  • 13

    Dec

HBI

Hanesbrands

$21.31

0.355 (1.69%)

13:15
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Options
HanesBrands put volume heavy and directionally bearish »

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DAL

Delta Air Lines

$53.49

-0.135 (-0.25%)

, BA

Boeing

$293.97

4.0261 (1.39%)

13:11
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Periodicals
Delta to order about 100 jets from Airbus, CNN says »

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DAL

Delta Air Lines

$53.49

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BA

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4.0261 (1.39%)

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  • 14

    Dec

SAFM

Sanderson Farms

$167.00

1.08 (0.65%)

13:09
12/13/17
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Earnings
Notable companies reporting before tomorrow's open »

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  • 14

    Dec

NDSN

Nordson

$124.22

-0.8 (-0.64%)

, PIR

Pier 1 Imports

$5.80

0.34 (6.23%)

13:09
12/13/17
12/13
13:09
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Earnings
Notable companies reporting after market close »

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NDSN

Nordson

$124.22

-0.8 (-0.64%)

PIR

Pier 1 Imports

$5.80

0.34 (6.23%)

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  • 14

    Dec

AMN

AMN Healthcare

$48.20

-0.1 (-0.21%)

13:09
12/13/17
12/13
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Conference/Events
AMN Healthcare management to meet with SunTrust »

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  • 13

    Dec

  • 14

    Dec

DECK

Deckers Brands

$78.28

1.15 (1.49%)

13:06
12/13/17
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Marcato poised to win in proxy battle with Deckers, Reuters reports »

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MDT

Medtronic

$81.66

-0.345 (-0.42%)

13:03
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Medtronic pays $12M in multistate settlement over marketing »

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SPX

S&P 500

, SPY

SPDR S&P 500 ETF Trust

$267.00

0.2237 (0.08%)

12:57
12/13/17
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Periodicals
Trump says would sign tax bill with 21% corporate rate, CNBC reports 

Reference Link

SPX

S&P 500

SPY

SPDR S&P 500 ETF Trust

$267.00

0.2237 (0.08%)

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AIZ

Assurant

$99.77

-0.53 (-0.53%)

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  • 13

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SPX

S&P 500

, SPY

SPDR S&P 500 ETF Trust

$267.23

0.45 (0.17%)

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LHCG

LHC Group

$61.60

0.39 (0.64%)

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  • 13

    Dec

TOSYY

Toshiba, also use TOSBF

$16.21

0.035 (0.22%)

, TOSBF

Toshiba, also use TOSYY

$2.69

0.004 (0.15%)

12:47
12/13/17
12/13
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TOSYY

Toshiba, also use TOSBF

$16.21

0.035 (0.22%)

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Toshiba, also use TOSYY

$2.69

0.004 (0.15%)

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DEA

Easterly Government Properties

$21.65

-0.025 (-0.12%)

12:45
12/13/17
12/13
12:45
12/13/17
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Conference/Events
Easterly Government Properties management to meet with SunTrust »

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  • 13

    Dec

  • 14

    Dec

BTC

Bitcoin

, BITCOIN

Bitcoin

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Gundlach says bitcoin can go higher, but 'something is wrong here' »

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BITCOIN

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FB

Facebook

$176.96

-2.08 (-1.16%)

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  • 11

    Jan

  • 07

    Feb

CHL

China Mobile

$49.23

0.29 (0.59%)

, BT

BT Group

$18.21

0.12 (0.66%)

12:44
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12:44
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Periodicals
China Mobile launches UK mobile phone service, FT reports »

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CHL

China Mobile

$49.23

0.29 (0.59%)

BT

BT Group

$18.21

0.12 (0.66%)

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BTC

Bitcoin

, BITCOIN

Bitcoin

12:41
12/13/17
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Hot Stocks
Gundlach says Bitcoin has entered 'silly season' »

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INDA

iShares MSCI India ETF

$34.98

0.06 (0.17%)

12:40
12/13/17
12/13
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Hot Stocks
Gundlach continues to 'love' India, recommends iShares MSCI India ETF »

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