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SNY

Sanofi

$47.97

-0.11 (-0.23%)

, AZN

AstraZeneca

$30.06

-0.11 (-0.36%)

07:56
08/08/17
08/08
07:56
08/08/17
07:56

Sanofi hopes to narrow gap in cancer drug race, Bloomberg says

French drugmaker Sanofi (SNY) is looking to narrow the gap in the race to develop new cancer drugs after competitors AstraZeneca (AZN) and Bristol-Myers (BMY) suffered setbacks in key studies, Bloomberg reports, citing Elias Zerhouni, president of global research and development. Sanofi is hoping to introduce a primary treatment for patients with lung cancer in a class of immune therapies, known as PD-1 inhibitors, in a market where Merck's (MRK) Keytruda is currently the only approved first line of treatment. Reference Link

SNY

Sanofi

$47.97

-0.11 (-0.23%)

AZN

AstraZeneca

$30.06

-0.11 (-0.36%)

BMY

Bristol-Myers

$56.30

0.35 (0.63%)

MRK

Merck

$62.84

-0.26 (-0.41%)

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    Nov

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    Mar

SNY Sanofi
$47.97

-0.11 (-0.23%)

07/10/17
PIPR
07/10/17
NO CHANGE
Target $126
PIPR
Overweight
Alnylam shares overreacting to ALT elevations in OLE data, says Piper Jaffray
Alnylam (ALNY) and partner Sanofi (SNY) presented new Phase II open-label extension study data on 33 hemophilia patients being treated with fitusiran and reported that eleven patients reported asymptomatic ALT increases, up from three observed in its ASH meeting update, noted Piper Jaffray analyst Edward Tenthoff. However, he thinks the stock is overreacting, as the liver enzyme elevations were asymptomatic and largely reversed within one month, he tells investors. Tenthoff, who also sees the efficacy data as encouraging, reiterates his Overweight rating and $126 price target on Alnylam shares.
07/31/17
ADAM
07/31/17
NO CHANGE
Target $522
ADAM
Buy
Dupixent authorization approval rate outweighs Q2 miss, says Canaccord
Regeneron (REGN) partner Sanofi (SNY) reported a "very high" 73%-83% prior authorization approval rate for Dupixent in Q2, which Canaccord analyst John Newman said outweighs the fact that sales for the drug at $30.6M were slightly below the $33M consensus forecast. The analyst, who sees rapid payor acceptance of Dupixent as "much more crucial" than the initial quarterly revenue, keeps a Buy rating and $522 price target on Regeneron shares.
07/31/17
PIPR
07/31/17
NO CHANGE
Target $557
PIPR
Overweight
Regeneron indicated lower after Sanofi earnings report, says Piper Jaffray
Piper Jaffray analyst Edward Tenthoff says shares of Regeneron (REGN) are indicated lower after partner Sanofi (SNY) reported Q2 U.S. Dupixent sales of $30M in adults with atopic dermatitis. This was essentially in line with the consensus estimate of $33M, Tenthoff tells investors in a research note. He adds that over 5,100 physicians have prescribed and over 13,000 atopic dermatitis patients have been prescribed Dupixent as of July 26. The analyst views the launch stats as impressive and reiterates an Overweight rating on Regeneron with a $557 price target.
07/14/17
WELS
07/14/17
NO CHANGE
Target $41
WELS
Outperform
Wells says smallpox vaccine deal an 'excellent fit' for Emergent BioSolutions
Wells Fargo analyst David Maris said Emergent BioSolutions' (EBS) deal to acquire the ACAM2000 smallpox vaccine business of Sanofi (SNY) is "an excellent fit" and he is "encouraged" by its ability to identify and make a deal for such a "solid target." Maris keeps an Outperform rating and $41 price target on Emergent BioSolutions.
AZN AstraZeneca
$30.06

-0.11 (-0.36%)

07/28/17
07/28/17
DOWNGRADE

On The Fly: Top five analyst downgrades
Catch up on today's top five analyst downgrades with this list compiled by The Fly: 1. Starbucks (SBUX) was downgraded to Neutral from Buy at Guggenheim and to Hold from Buy at Stifel. 2. Spirit Airlines (SAVE) was downgraded to Neutral from Buy at Buckingham and BofA/Merrill and to In-Line from Outperform at Imperial Capital. 3. Flowers Foods (FLO) downgraded to Hold from Buy at Jefferies with analyst Akshay Jagdale saying his positive thesis on bread industry pricing becoming more rational has not played out. 4. AstraZeneca (AZN) downgraded to Equal Weight from Overweight at Morgan Stanley with analyst Vincent Meunier saying shares look fairly valued as he removed MYSTIC from his models. 5. U.S. Steel (X) downgraded to Sell from Neutral at Citi with analyst Alexander Hacking saying he sees downside risk to U.S. flat rolled prices for the remainder of 2017. This list is just a portion of The Fly's full analyst coverage. To see The Fly's full Street Research coverage, click here.
07/28/17
LEER
07/28/17
NO CHANGE
Target $61
LEER
Outperform
Bristol-Myers price target lowered to $61 after Astra trial setback at Leerink
Leerink analyst Seamus Fernandez said Bristol-Myers (BMY) reported "solid" Q2 results, including encouraging growth for its key franchises, but he sees increased uncertainty following the failure of AstraZeneca's (AZN) MYSTIC trial, which has potential read through to Bristol's CheckMate-227 trial of its I/O combo of Opdivo + Yervoy. Fernandez lowered his price target on Bristol shares to $61 from $66, but "fully acknowledges" the range of differences in the trial designs. He keeps an Outperform rating on Bristol-Myers, citing prospects for monotherapy Opdivo approval in the second-line setting and success in first-line liver cancer.
07/28/17
RHCO
07/28/17
NO CHANGE
RHCO
Merck, AstraZeneca deal positive, says SunTrust
After Merck (MRK) paid $1.6B upfront for access to Astrazeneca's (AZN) PARP inhibitor, Lynparza and another drug, SunTrust analyst John Boris says that the deal "makes strategic/financial sense and validates the PARP inhibitor class." He adds that the companies are "ideally positioned" to leverage a combination of IO and PARP therapies. The analyst reiterates a $73 price target and a Buy rating on Merck.
08/01/17
PART
08/01/17
UPGRADE
PART
Hold
AstraZeneca upgraded to Hold from Sell at Pareto
BMY Bristol-Myers
$56.30

0.35 (0.63%)

07/27/17
LEER
07/27/17
NO CHANGE
LEER
Outperform
AstraZeneca trial failure negative for Bristol-Myers, says Leerink
Leerink analyst Seamus Fernandez notes that AstraZeneca (AZN) announced that the MYSTIC trial failed to show a progression-free survival benefit for Imfinzi + tremelimumab compared to chemotherapy in first-line non-small cell lung cancer patients with PDL1 expression greater than 25%. The read through is an obvious negative readthrough for Bristol-Myers' (BMY) combo of Opdivo + Yervoy in the ongoing CheckMate-227 trial, the analyst says. He points out that while there are several key differences in trial design between MYSTIC and CM-227, they are unlikely to result in meaningfully different outcomes. Fernandez reiterates an Outperform rating on Bristol-Myers' shares.
07/31/17
LEER
07/31/17
NO CHANGE
LEER
Outperform
Clovis weakness unwarranted after Bristol-Myers pact, says Leerink
Leerink analyst Michael Schmidt thinks today's weakness in Clovis (CLVS) is unwarranted following the company's clinical collaboration agreement with Bristol-Myers (BMY) and presents a buying opportunity. This deal does not preclude a future acquisition of the company, but it does increase the competitiveness and value of Rubraca, argues Schmidt, who reiterates his Outperform rating on Clovis shares.
07/31/17
JANY
07/31/17
NO CHANGE
Target $107
JANY
Buy
Clovis partnership undercuts takeover thesis, says Janney Capital
Janney Capital analyst Debjit Chattopadhyay says Clovis Oncology's (CLVS) clinical partnership with Bristol-Myer Squibb (BMY) undercuts his takeout thesis. The recent agreements across the PARP drugs implies no near-term takeovers, Chattopadhyay tells investors in a research note. He believes this will "likely to be disappointing to many." The analyst has a Buy rating on Clovis with a $107 price target. The shares in early trading are down $8.04, or 8% to $89.97.
MRK Merck
$62.84

-0.26 (-0.41%)

07/27/17
FBCO
07/27/17
NO CHANGE
FBCO
Merck unlikely to buy PARP company after Astra deal, says Credit Suisse
Credit Suisse analyst Alethia Young believes Merck (MRK) is unlikely to acquire a PARP inhibitor company like Tesaro (TSRO) or Clovis (CLVS) after inking an immuno-oncology deal with AstraZeneca (AZN).
07/27/17
GSCO
07/27/17
NO CHANGE
GSCO
Merck could trade up $5 following AstraZeneca MYSTIC failure, says Goldman Sachs
Goldman analyst Jami Rubin expects Merck (MRK) to trade up approximately $5 based on sentiment following AstraZeneca's MYSTIC failure as it partially de-risks longer-term estimates for Keytruda. As a result, the analyst raised Merck's Keytruda sales estimates by $600M in 2018 and $1B in 2019 and beyond, increasing earnings estimates by 14c-20c, and raising his price target on shares to $74 from $70. Rubin cautions that long-term estimates could be at risk if other competitor trials are successful. The analyst rates Merck a Neutral.
07/27/17
JANY
07/27/17
NO CHANGE
Target $107
JANY
Buy
PARP deals may make Clovis more attractive buyout candidate, says Janney
The partnerships announced today between AstraZeneca (AZN) and Merck (MRK) as well as Tesaro (TSRO) and Takeda highlight pharma's willingness to expand on PARP's, Janney analyst Debjit Chattopadhyay tells investors in a research note. Clovis' (CLVS) Rubraca is now the only unencumbered PARP and is "far cheaper" on a relative valuation basis than peer Tesaro, the analyst adds. He believes Clovis could now become a more compelling takeover candidate. Chattopadhyay has a Buy rating on the shares with a $107 price target. The stock in midday trading is up 7%, or $5.90, to $93.33.

TODAY'S FREE FLY STORIES

23:50
09/19/18
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23:50
General news
Nellie Liang »

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CRM

Salesforce

$152.88

-3.12 (-2.00%)

, CPCAY

Cathay Pacific

$0.00

(0.00%)

21:04
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Hot Stocks
Cathay Pacific to partner with Salesforce on digital transformation »

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Salesforce

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Cathay Pacific

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UCTT

Ultra Clean

$13.42

-0.13 (-0.96%)

21:02
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SPY

SPDR S&P 500 ETF Trust

$291.22

0.26 (0.09%)

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S&P 500

$0.00

(0.00%)

21:00
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21:00
General news
President Trump to nominate Nellie Liang to Federal Reserve Board of Governors »

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SPDR S&P 500 ETF Trust

$291.22

0.26 (0.09%)

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EB

Eventbrite

$0.00

(0.00%)

20:53
09/19/18
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Syndicate
Eventbrite 10M share IPO priced at $23.00 »

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EFX

Equifax

$134.27

-3.78 (-2.74%)

20:40
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20:40
Hot Stocks
Equifax UK arm fined GBP500K for security breach in 2017 »

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BSVN

Bank7

$0.00

(0.00%)

20:29
09/19/18
09/19
20:29
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20:29
Syndicate
Bank7 3.4M share IPO priced at $19.00 »

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THO

Thor Industries

$105.72

2.44 (2.36%)

, DRI

Darden

$117.90

-1.03 (-0.87%)

20:25
09/19/18
09/19
20:25
09/19/18
20:25
Earnings
Notable companies reporting before tomorrow's open »

Notable companies…

THO

Thor Industries

$105.72

2.44 (2.36%)

DRI

Darden

$117.90

-1.03 (-0.87%)

SANW

S&W Seed

$3.15

0.1 (3.28%)

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LGCY

Legacy Reserves

$4.78

-0.18 (-3.63%)

19:34
09/19/18
09/19
19:34
09/19/18
19:34
Initiation
Legacy Reserves initiated at Seaport Global »

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CMT

Core Molding

$7.75

-0.15 (-1.90%)

19:07
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Hot Stocks
Core Molding names Eric Palomaki VP of Operations »

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RMNI

Rimini Street

$6.92

0.33 (5.01%)

19:07
09/19/18
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19:07
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Hot Stocks
Rimini Street obtains Australian single touch payroll certification »

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MLHR

Herman Miller

$37.30

0.2 (0.54%)

, LCI

Lannett

$4.85

0.15 (3.19%)

18:56
09/19/18
09/19
18:56
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18:56
Hot Stocks
Fly Intel: After Hours Movers »

UP AFTER EARNINGS: Herman…

MLHR

Herman Miller

$37.30

0.2 (0.54%)

LCI

Lannett

$4.85

0.15 (3.19%)

AVP

Avon Products

$2.32

0.03 (1.31%)

NGD

New Gold

$1.10

0.03 (2.80%)

AMD

AMD

$31.20

-0.73 (-2.29%)

RHT

Red Hat

$143.38

0.59 (0.41%)

MTEM

Molecular Templates

$6.25

2.15 (52.44%)

CRSP

Crispr Therapeutics

$51.90

-1.27 (-2.39%)

KOS

Kosmos

$9.35

0.04 (0.43%)

VKTX

Viking Therapeutics

$19.64

0.17 (0.87%)

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LCI

Lannett

$4.85

0.15 (3.19%)

18:49
09/19/18
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Breaking Hot Stocks news story on Lannett »

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NKE

Nike

$84.43

-0.86 (-1.01%)

18:43
09/19/18
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18:43
Periodicals
Nike has sold out 61% more merchandise after Kaepernick ad, Reuters says »

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ADVM

Adverum Biotechnologies

$5.85

0.05 (0.86%)

18:38
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Hot Stocks
Adverum Biotechnologies receives fast track designation for ADVM022 gene therapy »

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BTI

British American Tobacco

$46.87

-0.475 (-1.00%)

18:11
09/19/18
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18:11
Hot Stocks
British American Tobacco CEO Durante to retire April 1, 2019 »

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KRNY

Kearny Financial

$13.75

0.25 (1.85%)

18:02
09/19/18
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18:02
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18:02
Hot Stocks
Kearny Financial declares special cash dividend of 16c per share »

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AVA

Avista

$51.50

0.01 (0.02%)

18:00
09/19/18
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Hot Stocks
Avista, Hydro One extend merger end date »

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AMZN

Amazon.com

$1,926.27

-14.93 (-0.77%)

17:57
09/19/18
09/19
17:57
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17:57
Periodicals
Amazon leaks new Alexa smart plug and a subwoofer, Verge says »

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FB

Facebook

$163.06

2.75 (1.72%)

17:45
09/19/18
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17:45
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Periodicals
Facebook sets up 'War Room' for safeguarding elections, NY Times says »

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  • 28

    Oct

RRTS

Roadrunner

$1.16

-0.065 (-5.33%)

17:45
09/19/18
09/19
17:45
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17:45
Syndicate
Roadrunner files S-1 for rights offering to existing holders »

Roadrunner announced that…

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ASB

Associated Banc-Corp

$26.45

0.3 (1.15%)

17:35
09/19/18
09/19
17:35
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17:35
Hot Stocks
Associated Banc-Corp announces $200M share repurchase program »

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BLIN

Bridgeline Digital

$1.02

-0.01 (-0.98%)

17:32
09/19/18
09/19
17:32
09/19/18
17:32
Syndicate
Breaking Syndicate news story on Bridgeline Digital »

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NGD

New Gold

$1.10

0.03 (2.80%)

17:29
09/19/18
09/19
17:29
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17:29
Hot Stocks
New Gold sells Mesquite Mine to Eqiunox Gold for $158M »

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  • 23

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SPX

S&P 500

$0.00

(0.00%)

, SPY

SPDR S&P 500 ETF Trust

$291.22

0.26 (0.09%)

17:23
09/19/18
09/19
17:23
09/19/18
17:23
Periodicals
Trudeau wants to see more U.S. flexibility around NAFTA, Reuters says »

Canadian prime minister…

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S&P 500

$0.00

(0.00%)

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SPDR S&P 500 ETF Trust

$291.22

0.26 (0.09%)

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