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CLRB

Cellectar Biosciences

$1.48

-0.03 (-1.99%)

08:39
08/22/17
08/22
08:39
08/22/17
08:39

Cellectar Biosciences announces 'significant' PDC platform advancement

Cellectar Biosciences announces that its Phospholipid Drug Conjugate research program has generated numerous PDC molecules that show significant improved pharmacologic activity versus the payload molecule alone. Utilizing a selection of novel linkers to attach proprietary cytotoxic molecules to the company's PDC platform, Cellectar has formulated new compounds specifically designed for improved tumor targeting and fewer off-target adverse effects. The research has demonstrated that with a variety of payloads, the phospholipid ether molecules provide, on average, a greater than 20-fold increase in delivery of the PDC to cancerous cells. To date, the company's research has demonstrated that the conjugated molecules are inactive until cleavage of the payload from the phospholipid ether. This mechanism provides significant opportunity to reduce the off-target impact and associated side effects of many chemotherapeutics. These data show greater than 500-fold dilution separation between effects in tumor cells and effects in normal cells, and that this separation can be controlled by the linker chemistry. Importantly, the company has also been able to show that its novel linker chemistry allows for the payload to be selectively cleaved within the tumor cells, resulting in significant potency.

  • 26

    Sep

CLRB Cellectar Biosciences
$1.48

-0.03 (-1.99%)

12/21/16
LTCO
12/21/16
INITIATION
Target $2.7
LTCO
Buy
Cellectar Biosciences initiated with a Buy at Ladenburg
Ladenburg Thalmann analyst Wangzhi Li started Cellectar Biosciences with a Buy rating and $2.70 price target.

TODAY'S FREE FLY STORIES

MLNX

Mellanox

$65.10

0.8 (1.24%)

16:10
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Technical Take: Mellanox at new 52-week high after results »

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  • 18

    Jan

IBM

IBM

$169.07

0.59 (0.35%)

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IBM reports Q4 Cognitive solutions revenue $5.4B, up 3% »

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  • 18

    Jan

AMNB

American National Bankshares

$39.10

-0.8 (-2.01%)

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PINC

Premier

$32.23

-0.02 (-0.06%)

16:09
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CERN

Cerner

$69.49

-0.79 (-1.12%)

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  • 06

    Feb

QGEN

Qiagen

$32.59

-0.3 (-0.91%)

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Qiagen granted FDA approval to expand use of EGFR test in lung cancer »

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IBM

IBM

$169.21

0.73 (0.43%)

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IBM reports Q4 cloud revenue $5.5B, up 30% »

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  • 18

    Jan

AXP

American Express

$99.88

-0.885 (-0.88%)

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American Express reports Q4 U.S. Consumer Services up 13% to $3.4B »

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  • 18

    Jan

GWGH

GWG Holdings

$8.10

-0.2 (-2.41%)

, BEN

Franklin Resources

$44.61

-0.29 (-0.65%)

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$8.10

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$44.61

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  • 30

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MDRX

Allscripts

$15.09

-0.21 (-1.37%)

16:08
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Initiation
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  • 15

    Feb

IBM

IBM

$169.18

0.53 (0.31%)

16:08
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Earnings
IBM reports Q4 adjusted EPS $5.18, consensus $5.17 »

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  • 18

    Jan

ATHN

athenahealth

$125.53

-0.65 (-0.52%)

16:08
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athenahealth initiated  »

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  • 02

    Feb

MLNX

Mellanox

$65.10

0.8 (1.24%)

16:07
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Earnings
Mellanox sees FY18 revenue $970M-$990M, consensus $971M »

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  • 18

    Jan

MLNX

Mellanox

$65.10

0.8 (1.24%)

16:07
01/18/18
01/18
16:07
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Earnings
Mellanox sees Q1 revenue $222M-$232M, consensus $220.3M »

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  • 18

    Jan

AMGN

Amgen

$187.59

-0.42 (-0.22%)

, AGN

Allergan

$179.82

3.1 (1.75%)

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Amgen and Allergan's Mvasi for certain cancers approved in Europe »

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AMGN

Amgen

$187.59

-0.42 (-0.22%)

AGN

Allergan

$179.82

3.1 (1.75%)

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TXN

Texas Instruments

$116.41

-2.75 (-2.31%)

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Texas Instruments: Brian Crutcher to become next CEO on June 1 »

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  • 23

    Jan

AXP

American Express

$99.90

-0.86 (-0.85%)

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  • 18

    Jan

MLNX

Mellanox

$65.10

0.8 (1.24%)

16:06
01/18/18
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Earnings
Mellanox reports Q4 adjusted EPS 82c, consensus 68c »

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  • 18

    Jan

AXP

American Express

$99.85

-0.9 (-0.89%)

16:06
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Earnings
American Express reports Q4 adjusted EPS $1.58, consensus $1.54 »

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  • 18

    Jan

TXN

Texas Instruments

$116.41

-2.75 (-2.31%)

16:05
01/18/18
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Hot Stocks
Breaking Hot Stocks news story on Texas Instruments »

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  • 23

    Jan

PBCT

People's United

$19.43

-0.02 (-0.10%)

16:04
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Earnings
People's United reports Q4 operating EPS 31c, consensus 27c »

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  • 18

    Jan

CRL

Charles River

$106.61

-0.16 (-0.15%)

16:04
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  • 18

    Jan

IQV

Iqvia

$99.83

-0.395 (-0.39%)

16:04
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Initiation
Iqvia initiated  »

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ICLR

Icon

$111.95

-0.93 (-0.82%)

16:04
01/18/18
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Initiation
Icon initiated  »

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CP

Canadian Pacific

$182.27

0.935 (0.52%)

16:03
01/18/18
01/18
16:03
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Earnings
Canadian Pacific sees FY18 EPS growth in double-digits »

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  • 18

    Jan

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