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AMGN

Amgen

$169.00

-1.07 (-0.63%)

18:46
08/23/17
08/23
18:46
08/23/17
18:46

Amgen: Lancet Oncology publishes survival analysis from KYPROLIS Phase 3 trial

Amgen announced that results from an overall survival analysis of the Phase 3 head-to-head ENDEAVOR trial were published online first in The Lancet Oncology. Data showed that KYPROLIS administered at 56 mg/m2 twice weekly and dexamethasone reduced the risk of death by 21% over Velcade and dexamethasone, resulting in a 7.6 month OS benefit (median OS 47.6 months for Kd56 versus 40.0 for Vd, HR=0.79; p=0.01). The OS benefit was consistent regardless of prior Velcade therapy (HR=0.75 for no prior Velcade; HR=0.84 for prior Velcade). This Kd56 regimen is already approved in the U.S., European Union and other countries based on the primary analysis of progression-free survival in the ENDEAVOR study. "These results showed KYPROLIS and dexamethasone significantly reduced the risk of death compared to Velcade and dexamethasone in patients with relapsed or refractory multiple myeloma," said study co-author and investigator Meletios A. Dimopoulos, M.D., professor of Clinical Therapeutics at the National and Kapodistrian University of Athens, School of Medicine. "These results support the use of KYPROLIS and dexamethasone as a standard of care for multiple myeloma patients at first relapse."

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AMGN Amgen
$169.00

-1.07 (-0.63%)

07/18/17
PIPR
07/18/17
NO CHANGE
Target $14
PIPR
Overweight
Piper says Array deal with Amgen 'another example' of successful partnering
Commenting on Array Biopharma's (ARRY) announcement of a preclinical autoimmune partnership deal with Amgen (AMGN), Piper Jaffray analyst Edward Tenthoff called the agreement "yet another example of Array successfully partnering its discoveries" and raising non-dilutive capital. Tenthoff keeps an Overweight rating and $14 price target on Array Biopharma shares.
07/26/17
BMOC
07/26/17
DOWNGRADE
BMOC
Market Perform
Amgen downgraded to Market Perform from Outperform at BMO Capital
07/26/17
OPCO
07/26/17
NO CHANGE
Target $203
OPCO
Outperform
Amgen price target raised to $203 from $189 at Oppenheimer
Oppenheimer analyst Leah Rush Cann raised her price target for Amgen to $203 from $189 after the company reported "strong" Q2 results. The analyst reiterates an Outperform rating on the shares.
07/26/17
BMOC
07/26/17
DOWNGRADE
BMOC
Market Perform
Amgen downgraded on valuation lack of near-term catalysts at BMO Capital
As noted earlier, BMO Capital downgraded Amgen to Market Perform from Outperform. Analyst M. Ian Somaiya downgraded the stock based on valuation and his belief that American College of Cardiology guidelines probably won't be updated until late 2018, likely preventing a positive turning point in Repatha sales until 2019. Target $199.

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TISI

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PZZA

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OGS

One Gas

$68.99

0.08 (0.12%)

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OGS

One Gas

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Spirit Airlines

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OGS

One Gas

$68.99

0.08 (0.12%)

16:30
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One Gas sees 5%-7% EPS growth from 2017-2022 »

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Preliminary option volume of 28.8M today »

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OGS

One Gas

$68.99

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OGS

One Gas

$68.99

0.08 (0.12%)

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IDCC

InterDigital

$79.40

-1.3 (-1.61%)

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$68.99

0.08 (0.12%)

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INTC

Intel

$43.14

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AMD

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$43.14

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AMGP

Antero Midstream GP

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  • 18

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Antero Midstream Partners

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  • 18

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ESP

Espey Mfg

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QTM

Quantum

$6.07

-0.07 (-1.14%)

, GUID

Guidance Software

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Quantum appoints Patrick Dennis as CEO »

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Quantum

$6.07

-0.07 (-1.14%)

GUID

Guidance Software

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VIX

Volatility Index S&P 500 Options

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Options
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BA

Boeing

$335.16

-1.05 (-0.31%)

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Adient

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Boeing

$335.16

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ADNT

Adient

$82.18

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CLD

Cloud Peak

$5.31

-0.24 (-4.32%)

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GDEN

Golden Entertainment

$31.70

-0.48 (-1.49%)

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Syndicate
Golden Entertainment files to sell 6.5M shares of common stock for holders »

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ATEN

A10 Networks

$7.31

-0.27 (-3.56%)

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Breaking Hot Stocks news story on A10 Networks »

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