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ZGNX

Zogenix

$14.30

-0.85 (-5.61%)

13:15
09/15/17
09/15
13:15
09/15/17
13:15

Zogenix put volume heavy and directionally bearish

Bearish flow noted in Zogenix with 5,504 puts trading, or 5x expected. Most active are Oct-17 5 puts and Oct-17 3 puts, with total volume in those strikes near 2,800 contracts. The Put/Call Ratio is 5.25, while ATM IV is up nearly 21 points on the day. Earnings are expected on November 7th.

ZGNX Zogenix
$14.30

-0.85 (-5.61%)

09/06/17
MZHO
09/06/17
INITIATION
Target $28
MZHO
Buy
Zogenix initiated with a Buy at Mizuho
Mizuho initiated Zogenix with a Buy and a $28 price target.
12/05/16
12/05/16
NO CHANGE

Zogenix announces new data for ZX008
Zogenix announced new data demonstrating effectiveness and cardiovascular-related safety for patients treated with ZX008 as an adjunctive therapy for seizures associated with Lennox Gastaut Syndrome, or LGS, and continued effectiveness and safety for the on-going open-label patients with Dravet syndrome. The data were presented at the 70th Annual American Epilepsy Society meeting, taking place this week in Houston, Texas. The LGS data presented were from an interim analysis of the first 13 patients to have completed at least 12 weeks of a Phase 2 open-label, dose-finding investigator-initiated study, led by Lieven Lagae, M.D., Ph.D., Professor at the University of Leuven, Belgium, Head of the Pediatric Neurology Department and Director of the Childhood Epilepsy Program at the University of Leuven Hospitals. Patients enrolled in the study were 3-18 years of age diagnosed with LGS with at least four convulsive seizures and on at least two anti-epileptic drugs, or AEDs, at stable doses in the four weeks prior to study initiation. Participants were treated with ZX008 as an add-on therapy for up to 20 weeks starting at 0.2mg/kg/day. The dose could be titrated at four-week intervals based on treatment response up to a maximum of 0.8 mg/kg/day if the patient did not reach at least a 50% reduction in major motor seizure frequency. It is important to note that, per protocol, dose escalation stopped when a patient's major motor seizure frequency was reduced by greater than or equal to 50% of baseline. The mean age of participants was 11.4 years and they had failed a median of five antiepileptic therapies prior to this study. At study initiation, patients were receiving a median of four antiepileptic therapies. The median number of major motor seizures during the four-week baseline period was 60. In the Intent-to-Treat, or ITT, patient population, there was a median 50% reduction in seizure frequency over the entire treatment period compared to baseline, with seven patients to date achieving a greater than or equal to 50% reduction in the number of major motor seizures in this step dose study.
11/11/16
AGIS
11/11/16
INITIATION
Target $28
AGIS
Buy
Zogenix initiated with a Buy at Aegis
Target $28.
10/04/16
LEER
10/04/16
INITIATION
Target $17
LEER
Outperform
Zogenix reinstated with an Outperform at Leerink
Leerink analyst Paul Matteis resumed coverage of Zogenix with an Outperform rating and $17 price target.

TODAY'S FREE FLY STORIES

JOE

Saint Joe Co.

$18.60

0.45 (2.48%)

16:46
09/22/17
09/22
16:46
09/22/17
16:46
Hot Stocks
Breaking Hot Stocks news story on Saint Joe Co. »

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16:40
09/22/17
09/22
16:40
09/22/17
16:40
General news
Moody's downgrades UK's rating to Aa2, changes outlook to stable »

Moody's Investors…

A

Agilent

$65.78

-0.14 (-0.21%)

, MRK

Merck

$65.13

-0.47 (-0.72%)

16:36
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09/22
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Agilent receives expanded FDA approval for the use of Dako PD-L1 IHC 22C3 »

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A

Agilent

$65.78

-0.14 (-0.21%)

MRK

Merck

$65.13

-0.47 (-0.72%)

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  • 22

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TYHT

Shineco

$3.23

-0.45 (-12.23%)

16:35
09/22/17
09/22
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Shineco enters into strategic cooperation to establish Apocynum Industrial Park »

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ARCI

Appliance Recycling

$1.16

0.03 (2.65%)

16:34
09/22/17
09/22
16:34
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16:34
Hot Stocks
Appliance Recycling gets written notice of default »

On September 20,…

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RNVA

Rennova Health

$0.22

0.0086 (4.07%)

16:31
09/22/17
09/22
16:31
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16:31
Hot Stocks
Rennova Health announces 1 for 15 reverse stock split »

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ARCI

Appliance Recycling

$1.16

0.03 (2.65%)

16:31
09/22/17
09/22
16:31
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16:31
Hot Stocks
Breaking Hot Stocks news story on Appliance Recycling »

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16:30
09/22/17
09/22
16:30
09/22/17
16:30
Options
Preliminary option volume of 13.9M today »

Preliminary option volume…

EKSO

Ekso Bionics

$1.28

0.14 (12.28%)

16:23
09/22/17
09/22
16:23
09/22/17
16:23
Hot Stocks
Ekso Bionics awarded government contract »

The Department of…

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UNH

UnitedHealth

$193.03

-2.18 (-1.12%)

, AET

Aetna

$153.57

0.18 (0.12%)

16:22
09/22/17
09/22
16:22
09/22/17
16:22
General news
On The Fly: Top stock stories for Friday »

The major averages…

UNH

UnitedHealth

$193.03

-2.18 (-1.12%)

AET

Aetna

$153.57

0.18 (0.12%)

ANTM

Anthem

$182.86

-0.64 (-0.35%)

CI

Cigna

$182.74

0.61 (0.33%)

AAPL

Apple

$151.89

-1.5 (-0.98%)

FSLR

First Solar

$51.41

2.65 (5.43%)

FINL

Finish Line

$9.73

0.51 (5.53%)

ASND

Ascendis Pharma

$34.24

6.5 (23.43%)

VSAR

Versartis

$2.68

-18.925 (-87.62%)

ICPT

Intercept

$61.59

-12.11 (-16.43%)

03/08/13
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  • 22

    Sep

  • 22

    Oct

DLR

Digital Realty

$114.51

-1.72 (-1.48%)

16:19
09/22/17
09/22
16:19
09/22/17
16:19
Syndicate
Breaking Syndicate news story on Digital Realty »

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$NSD

NASDAQ Market Internals

16:17
09/22/17
09/22
16:17
09/22/17
16:17
Technical Analysis
NASDAQ market internals summary »

Volume was average for…

03/08/13
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TSS

TSYS

$69.09

0.28 (0.41%)

16:16
09/22/17
09/22
16:16
09/22/17
16:16
Hot Stocks
TSYS announces resignation of COO Pamela Joseph »

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$NYE

NYSE Market Internals

16:16
09/22/17
09/22
16:16
09/22/17
16:16
Technical Analysis
NYSE market internals summary »

Volume was below average…

03/08/13
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FB

Facebook

$170.54

-0.57 (-0.33%)

16:15
09/22/17
09/22
16:15
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16:15
Hot Stocks
Facebook's Zuckerberg plans to sell up to 75M shares to fund charity initiatives »

On September 22 Mr.…

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  • 03

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  • 22

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IDA

IDACORP

$87.79

-0.73 (-0.82%)

16:13
09/22/17
09/22
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16:13
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IDACORP raises quarterly dividend 7.3% to 59c per share »

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VLRX

Valeritas

$3.06

-0.23 (-6.99%)

16:13
09/22/17
09/22
16:13
09/22/17
16:13
Syndicate
Valeritas announces common stock purchase agreement by Aspire Capital »

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FB

Facebook

$170.54

-0.57 (-0.33%)

16:12
09/22/17
09/22
16:12
09/22/17
16:12
Hot Stocks
Facebook dumps plan for new class of shares »

On September 21 the board…

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  • 03

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  • 22

    Oct

DCIX

Diana Containerships

$0.42

-0.0373 (-8.16%)

16:11
09/22/17
09/22
16:11
09/22/17
16:11
Hot Stocks
Diana Containerships announces one-for-three reverse stock split »

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SEP

Spectra Energy Partners

$43.89

0.34 (0.78%)

16:10
09/22/17
09/22
16:10
09/22/17
16:10
Syndicate
Breaking Syndicate news story on Spectra Energy Partners »

Spectra Energy Partners…

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SEV

Sevcon

$22.04

0.04 (0.18%)

, BWA

BorgWarner

$50.00

0.41 (0.83%)

16:10
09/22/17
09/22
16:10
09/22/17
16:10
Hot Stocks
Sevcon stockholders approve acquisition by BorgWarner »

Sevcon (SEV) announced…

SEV

Sevcon

$22.04

0.04 (0.18%)

BWA

BorgWarner

$50.00

0.41 (0.83%)

03/08/13
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  • 22

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  • 26

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ATOS

Atossa Genetics

$0.49

-0.0296 (-5.71%)

16:07
09/22/17
09/22
16:07
09/22/17
16:07
Syndicate
Breaking Syndicate news story on Atossa Genetics  »

Atossa Genetics files…

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CB

Chubb

$142.68

-0.27 (-0.19%)

16:06
09/22/17
09/22
16:06
09/22/17
16:06
Hot Stocks
Chubb CEO issues statement on EU-U.S. covered agreement »

Evan Greenberg, Chairman…

03/08/13
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  • 27

    Oct

  • 31

    Jan

AAPL

Apple

$153.39

-2.68 (-1.72%)

15:40
09/22/17
09/22
15:40
09/22/17
15:40
Options
Active trading in Apple as iPhone 8 makes a debut »

Active trading in Apple…

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  • 22

    Oct

MRK

Merck

15:39
09/22/17
09/22
15:39
09/22/17
15:39
Hot Stocks
Merck gets FDA approval for Keytruda »

Merck announced that the…

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  • 22

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  • 08

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