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NVCR

Novocure

$21.50

-0.1 (-0.46%)

18:27
09/24/17
09/24
18:27
09/24/17
18:27

Combination of Novocure Optune with Temozolomide demonstrates five-year survival

Novocure announced today results from its phase 3 pivotal EF-14 trial adding Optune to temozolomide for the treatment of newly diagnosed glioblastoma, or GBM, including results from health-related quality of life analyses, were presented at the American Society for Radiation Oncology's 2017 Annual Meeting in San Diego. Novocure's EF-14 phase 3 pivotal trial demonstrated "unprecedented" five-year survival results in newly diagnosed GBM. Patients treated with Optune in combination with temozolomide experienced a significant extension of overall survival without added toxicity compared to patients treated with temozolomide alone. The data also showed that Optune-treated patients were able to maintain quality of life for longer compared to patients treated with temozolomide alone. The EF-14 data showed median overall survival was extended by nearly five months for patients who received Optune in combination with temozolomide versus patients who received temozolomide alone. When measured annually for five consecutive years, patients treated with Optune in combination with temozolomide maintained superior rates of survival in newly diagnosed GBM versus patients treated with temozolomide alone. The five-year survival rate was 13% for patients treated with Optune together with temozolomide versus five percent for patients treated with temozolomide alone. The EF-14 data also showed that Optune with temozolomide did not negatively impact health-related quality of life, except for itchy skin. The combination treatment of Optune with temozolomide improved deterioration-free survival of several predefined health-related quality of life scales, compared to treatment with temozolomide alone.

NVCR Novocure
$21.50

-0.1 (-0.46%)

09/06/17
MZHO
09/06/17
INITIATION
Target $25
MZHO
Buy
Novocure initiated with a Buy at Mizuho
Mizuho initiated Novocure with a Buy and a $25 price target.
07/28/17
WEDB
07/28/17
NO CHANGE
WEDB
Outperform
Novocure should be bought on post-earnings pullback, says Wedbush
Wedbush analyst Tao Levy attributes the post-earnings pullback in Novocure to confusion regarding the comparison of the company's reported revenue to the published consensus estimate, but he does not believe it is an "apples-to-apples" comparison. Levy, who said that Optune prescriptions and active patients are "significantly" ahead of expectations, recommends buying the stock on the confusion and keeps an Outperform rating on the shares, which are down 1% in early trading.
07/12/17
WEDB
07/12/17
NO CHANGE
WEDB
Novocure removed from Best Ideas List at Wedbush
Wedbush removed Novocure from its Best Ideas List based on valuation.
05/24/17
WELS
05/24/17
UPGRADE
Target $15
WELS
Outperform
Novocure upgraded to Outperform from Market Perform at Wells Fargo
Wells Fargo analyst Larry Biegelsen upgraded Novocure to Outperform and raised his price target for the shares to $15 from $11.50. Feedback from consultants suggest that physician impression of Optune may be improving, Biegelsen tells investors in a research note. The consultants believe that the 5-year safety/efficacy results from EF-14 trial, which showed continued survival benefit, is "meaningful and would be hard to ignore," even for doctors previously skeptical of Optune for treating glioblastoma, the analyst adds.

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KALV

KalVista

$11.26

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Jaguar Health

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TSLA

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ASB

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CNXR

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GE

General Electric

$23.83

0.25 (1.06%)

, PG

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IL

Bought by SNCR

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MKL

Markel

$1,078.23

14.88 (1.40%)

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RYTM

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