Breaking News Instant updates and real-time market news.

ECYT

Endocyte

$1.41

0.05 (3.68%)

10:46
10/02/17
10/02
10:46
10/02/17
10:46

Endocyte jumps over 80% after 'transformational' transaction

Endocyte announced the completion of an exclusive worldwide license of PSMA-617 from ABX GmbH. Endocyte intends to move quickly into Phase 3 development of 177Lu-PSMA-617, a radioligand therapeutic, RLT, that targets the prostate-specific membrane antigen, PSMA, present in approximately 80% of patients with metastatic castration-resistant prostate cancer, mCRPC...This transaction is transformational to Endocyte, accelerating our path to commercialization. 177Lu-PSMA-617 has the potential to be the first-in-class RLT to address both bone and soft tissue disease, and it is profoundly important to the many patients suffering from mCRPC," said Mike Sherman, president and CEO of Endocyte. "Our experience with PSMA targeting and companion imaging development, in addition to our relationships with distinguished prostate cancer investigators from around the world, uniquely position Endocyte to lead this therapy to registration. We intend to seek regulatory approval to initiate a Phase 3 registration trial of 177Lu-PSMA-617 in early 2018. By focusing the company's resources on the execution of this program, we project trial completion as early as 2020." Under the terms of the agreement, Endocyte has exclusive worldwide rights to develop and commercialize PSMA-617. Endocyte has made an upfront payment of $12 million to ABX. In addition, Endocyte issued 2 million shares of Endocyte common stock to ABX and issued a warrant for the purchase of up to 4 million additional shares of Endocyte common stock. ABX is eligible for regulatory and commercial milestones of up to $160 million, and tiered royalties beginning in the mid-teens. Shares of Endocyte are up 80% to $2.53 in morning trading.

  • 02

    Oct

ECYT Endocyte
$1.41

0.05 (3.68%)

06/05/17
WEDB
06/05/17
DOWNGRADE
WEDB
Neutral
Endocyte downgraded to Neutral from Outperform at Wedbush
06/05/17
COWN
06/05/17
DOWNGRADE
COWN
Market Perform
Endocyte downgraded to Market Perform at Cowen
As reported previously, Cowen analyst Boris Peaker downgraded Endocyte to Market Perform from Outperform due to the failure of its lead asset, EC1456, and higher uncertainty with its pipeline.
06/05/17
WEDB
06/05/17
DOWNGRADE
WEDB
Neutral
Endocyte downgraded on clinical data, pipeline changes at Wedbush
As noted earlier, Wedbush downgraded Endocyte to Neutral from Outperform. Analyst David Nierengarten downgraded the stock after the company reported that the level of activity observed in trials did not support further development of its EC1456 or its EC1169 in taxane-naive CRPC. The company will only develop EC1169 in the taxanes-exposed CRPC population going forward and will discontinue EC1456, the analyst reported. He removed all sales from both drugs from his model ,citing uncertain initial results of 1169 in the taxane-exposed population. Target to $2 from $8.
06/05/17
06/05/17
DOWNGRADE

On The Fly: Top five analyst downgrades
Catch up on today's top five analyst downgrades with this list compiled by The Fly: 1. Apple (AAPL) downgraded to Sector Weight from Overweight at Pacific Crest with analyst Andy Hargreaves saying upside from the launch of iPhone 8 is already reflected in the shares. An "extremely strong iPhone 8 cycle" is being priced into the stock while little weight is being given to gross margins, supply issues, or the likelihood for declines beyond the iPhone 8, Hargreaves tells investors in a research note. 2. Perrigo (PRGO) downgraded to Underperform from Sector Perform at RBC Capital with analyst Randall Stanicky saying the growth rate of the company's U.S. consumer business "has structurally re-rated lower" amid pricing headwinds and share losses. 3. Endocyte (ECYT) downgraded to Neutral from Outperform at Wedbush and to Market Perform from Outperform at Cowen. 4. Affiliated Managers (AMG) was downgraded to Neutral from Buy at Citi while Federated Investors (FII) was downgraded to Sell from Neutral. 5. Veeva (VEEV) downgraded to Equal Weight from Overweight at Morgan Stanley with the firm's analyst saying the 60%+ move in shares year-to-date captures much of the near-term upside in the stock. This list is just a portion of The Fly's full analyst coverage. To see The Fly's full Street Research coverage, click here.

TODAY'S FREE FLY STORIES

BA

Boeing

$356.95

0.94 (0.26%)

19:10
07/17/18
07/17
19:10
07/17/18
19:10
Hot Stocks
Boeing awarded $3.9B government contract »

Boeing has been awarded a…

03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

  • 25

    Jul

MRTN

Marten Transport

$22.10

(0.00%)

, UAL

United Continental

$72.66

0.38 (0.53%)

19:03
07/17/18
07/17
19:03
07/17/18
19:03
Hot Stocks
On The Fly: After Hours Movers »

UP AFTER EARNINGS: Martin…

MRTN

Marten Transport

$22.10

(0.00%)

UAL

United Continental

$72.66

0.38 (0.53%)

CSX

CSX

$64.42

0.46 (0.72%)

MLNX

Mellanox

$84.85

0.9 (1.07%)

IBKR

Interactive Brokers

$64.65

1.93 (3.08%)

HCSG

Healthcare Services

$42.38

-0.3297 (-0.77%)

TXN

Texas Instruments

$115.80

1.21 (1.06%)

SAH

Sonic Automotive

$20.45

0.3 (1.49%)

CARA

Cara Therapeutics

$21.60

0.435 (2.06%)

CASI

Casi Pharmaceuticals

$7.26

-0.215 (-2.88%)

TLYS

Tilly's

$15.35

0.21 (1.39%)

CLX

Clorox

$135.00

0.71 (0.53%)

03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

  • 17

    Jul

  • 17

    Jul

  • 17

    Jul

  • 17

    Jul

  • 18

    Jul

  • 18

    Jul

  • 24

    Jul

  • 02

    Aug

  • 26

    Aug

  • 19

    Jul

BHP

BHP Billiton

$48.73

0.24 (0.49%)

18:38
07/17/18
07/17
18:38
07/17/18
18:38
Hot Stocks
BHP Billiton sees FY19 copper equivalent output broadly in line with FY18 »

Says expects to achieve…

03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

BHP

BHP Billiton

$48.73

0.24 (0.49%)

18:35
07/17/18
07/17
18:35
07/17/18
18:35
Hot Stocks
BHP Billiton reports Q4 petroleum production 49 MMBOE, down 6% »

Reports Q4 copper…

03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

CLX

Clorox

$135.00

0.71 (0.53%)

18:31
07/17/18
07/17
18:31
07/17/18
18:31
Downgrade
Clorox rating change  »

Clorox downgraded to Sell…

03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

  • 02

    Aug

NCS

NCI Building

$20.70

0.15 (0.73%)

18:27
07/17/18
07/17
18:27
07/17/18
18:27
Hot Stocks
NCI Building Systems, Ply Gem Parent to combine in stock-for-stock merger »

NCI Building Systems and…

03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

AMX

America Movil, also tag AMOV

$17.39

-0.35 (-1.97%)

, AMOV

America Movil, also tag AMX

$17.45

-0.19 (-1.08%)

18:16
07/17/18
07/17
18:16
07/17/18
18:16
Earnings
America Movil reports Q2 operating profit MXN32.6M, up 4.8% from last year »

Reports Q2 revenue…

AMX

America Movil, also tag AMOV

$17.39

-0.35 (-1.97%)

AMOV

America Movil, also tag AMX

$17.45

-0.19 (-1.08%)

03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

AMZN

Amazon.com

$1,844.00

21.98 (1.21%)

18:08
07/17/18
07/17
18:08
07/17/18
18:08
Recommendations
Amazon.com analyst commentary  »

Amazon.com price target…

03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

  • 18

    Jul

  • 26

    Jul

  • 16

    Aug

BRK.A

Berkshire Hathaway

$288,482.00

-1118 (-0.39%)

, BRK.B

Berkshire Hathaway

$190.47

-1.52 (-0.79%)

18:06
07/17/18
07/17
18:06
07/17/18
18:06
Hot Stocks
Berkshire Hathaway amends share repurchase program »

The Board of Directors of…

BRK.A

Berkshire Hathaway

$288,482.00

-1118 (-0.39%)

BRK.B

Berkshire Hathaway

$190.47

-1.52 (-0.79%)

03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

PNFP

Pinnacle Financial

$60.10

-0.5 (-0.83%)

18:02
07/17/18
07/17
18:02
07/17/18
18:02
Earnings
Pinnacle Financial reports Q2 EPS $1.15, consensus $1.14 »

Reports Q2 revenue…

03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

  • 18

    Jul

  • 24

    Sep

CHDN

Churchill Downs

$304.60

1.1 (0.36%)

18:02
07/17/18
07/17
18:02
07/17/18
18:02
Hot Stocks
Churchill Downs receives approval to increase historical racing machines »

Churchill Downs announced…

03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

  • 02

    Aug

CE

Celanese

$110.22

1.6 (1.47%)

18:01
07/17/18
07/17
18:01
07/17/18
18:01
Hot Stocks
Celanese announces acetic acid price increases in Asia »

Celanese Corporation will…

03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

  • 20

    Jul

BLK

BlackRock

$504.89

1.14 (0.23%)

17:51
07/17/18
07/17
17:51
07/17/18
17:51
Hot Stocks
BlackRock raises quarterly dividend to $3.13 from $2.88 per share »

The dividend is payable…

03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

DRNA

Dicerna

$12.47

0.57 (4.79%)

17:45
07/17/18
07/17
17:45
07/17/18
17:45
Conference/Events
Dicerna management to meet with SunTrust »

Group dinner to be held…

03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

  • 17

    Jul

GOOG

Alphabet

$1,198.81

14.57 (1.23%)

, GOOGL

Alphabet Class A

$1,213.65

17.07 (1.43%)

17:44
07/17/18
07/17
17:44
07/17/18
17:44
Periodicals
Google faces record EU fine over Android dominance, FT reports »

Alphabet's Google…

GOOG

Alphabet

$1,198.81

14.57 (1.23%)

GOOGL

Alphabet Class A

$1,213.65

17.07 (1.43%)

03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

  • 17

    Jul

  • 17

    Jul

  • 23

    Jul

  • 23

    Jul

  • 08

    Aug

  • 18

    Sep

  • 28

    Oct

BA

Boeing

$356.95

0.94 (0.26%)

17:39
07/17/18
07/17
17:39
07/17/18
17:39
Periodicals
Breaking Periodicals news story on Boeing »

Boeing awarded $3.9B…

03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

  • 25

    Jul

GWR

Genesee & Wyoming

$80.62

-0.88 (-1.08%)

17:34
07/17/18
07/17
17:34
07/17/18
17:34
Hot Stocks
Genesee & Wyoming reports June total traffic down 1.2% »

G&W's total…

03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

  • 27

    Jul

BLMN

Bloomin' Brands

$20.79

0.07 (0.34%)

17:19
07/17/18
07/17
17:19
07/17/18
17:19
Recommendations
Bloomin' Brands analyst commentary at Tigress Financial »

Current pullback in…

03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

  • 30

    Jul

TLYS

Tilly's

$15.35

0.21 (1.39%)

17:13
07/17/18
07/17
17:13
07/17/18
17:13
Syndicate
Breaking Syndicate news story on Tilly's »

Tilly's files to…

03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

UUUU

Energy Fuels

$2.30

0.03 (1.32%)

, URG

UR-Energy

$0.66

-0.0068 (-1.02%)

17:10
07/17/18
07/17
17:10
07/17/18
17:10
Periodicals
Trump admin plans to probe uranium imports, may lead to tariffs, Bloomberg says »

The Trump administration…

UUUU

Energy Fuels

$2.30

0.03 (1.32%)

URG

UR-Energy

$0.66

-0.0068 (-1.02%)

CCJ

Cameco

$10.93

0.16 (1.49%)

WWR

Westwater Resources

$0.37

-0.0023 (-0.62%)

UEC

Uranium Energy

$1.55

-0.015 (-0.96%)

03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

  • 19

    Jul

BPI

Bridgepoint Education

$7.01

0.215 (3.17%)

17:08
07/17/18
07/17
17:08
07/17/18
17:08
Hot Stocks
Bridgepoint Education receives approval to merge subsidiary institutions »

Bridgepoint Education…

03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

  • 25

    Jul

HTH

Hilltop Holdings

$21.49

-0.39 (-1.78%)

17:06
07/17/18
07/17
17:06
07/17/18
17:06
Hot Stocks
Hilltop Holdings announces approval for $85M Bank of River Oaks acquisition »

Hilltop Holdings and The…

03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

  • 27

    Jul

  • 24

    Sep

HWC

Hancock Whitney Corporation

$48.35

-0.1 (-0.21%)

17:03
07/17/18
07/17
17:03
07/17/18
17:03
Earnings
Hancock Whitney Corporation reports Q2 adjusted EPS 96c, consensus 95c »

Reports Q2 revenue…

03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

  • 18

    Jul

MEOH

Methanex

$71.15

1.4 (2.01%)

17:03
07/17/18
07/17
17:03
07/17/18
17:03
Hot Stocks
Methanex reaches long-term pact for natural gas supply to New Zealand ops »

Methanex announced that…

03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

TXN

Texas Instruments

$115.80

1.21 (1.06%)

17:01
07/17/18
07/17
17:01
07/17/18
17:01
Hot Stocks
Breaking Hot Stocks news story on Texas Instruments »

Texas Instruments down…

03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

  • 24

    Jul

Get Full Fly Access

Breaking market intelligence sent straight to you
Our team of experts analyze every news story and filter out the noise to deliver real-time market moving news.
Up-to-date information on important industry events
Get real-time updates on events that are moving the market—from conferences and calls to syndicate announcements.
News focused on the companies in your portfolio
Create up to 12 portfolios with 150 stocks each, and see how active they are in market news.