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KDMN

Kadmon

$3.91

0.29 (8.01%)

08:13
10/06/17
10/06
08:13
10/06/17
08:13

Kadmon receives orphan drug designation for KD025 for treatment of cGVHD

Kadmon announced that the U.S. Food and Drug Administration has granted orphan drug designation to KD025, the company's Rho-associated coiled-coil kinase inhibitor, for the treatment of chronic graft-versus-host disease, a serious complication following allogeneic bone marrow or stem cell transplantation. KD025 is being studied in an ongoing Phase 2 clinical trial in adults with steroid-dependent or steroid-refractory cGVHD and active disease. The dose-finding study includes 48 patients divided into three cohorts at different dose levels, enrolled sequentially following a safety assessment of each cohort. As previously reported, in a preliminary analysis of data from the lowest-dose cohort, KD025 200 mg QD demonstrated clinically meaningful responses, with no drug-related serious adverse events recorded.

  • 17

    Oct

KDMN Kadmon
$3.91

0.29 (8.01%)

03/14/17
PIPR
03/14/17
INITIATION
Target $7
PIPR
Overweight
Kadmon initiated with an Overweight at Piper Jaffray
Piper Jaffray analyst Edward Tenthoff started Kadmon Holdings with an Overweight rating and $7 price target.
03/16/17
WBBS
03/16/17
UPGRADE
WBBS
Hold
Kadmon upgraded to Hold from Sell at WBB Securities
WBB Securities analyst Stephen Brozak upgraded Kadmon to Hold.
07/11/17
PIPR
07/11/17
NO CHANGE
Target $7
PIPR
Overweight
Kadmon interim Phase II data 'impressive,' says Piper Jaffray
Piper Jaffray analyst Edward Tenthoff views Kadmon's preliminary Phase II data for KD025 in graft versus host disease patients as "impressive." Safety was "clean" and the primary endpoint was met, Tenthoff tells investors in a research note. He reiterates an Overweight rating on the shares with a $7 price target.
08/02/17
PIPR
08/02/17
NO CHANGE
Target $7
PIPR
Overweight
Imbruvica approval in graft versus host positive for Kadmon, says Piper Jaffray
After the FDA expanded the approval of AbbVie (ABBV) and Johnson & Johnson's (JNJ) Imbruvica for the treatment of adults with chronic graft versus host disease, or cGVHD, Piper Jaffray analyst Edward Tenthoff said he views the news as positive for Kadmon's KD025. Imbruvica is tough for patients to tolerate, said Tenthoff, who sees an opportunity for KD025 to more safely treat cGVHD patients. He keeps an Overweight rating and $7 price target on Kadmon shares.

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CLI

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TGB

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BAND

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BAND

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SM

SM Energy

$21.30

-0.54 (-2.47%)

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  • 22

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BAND

Bandwidth

$24.09

0.18 (0.75%)

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SM

SM Energy

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P

Pandora

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SM

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P

Pandora

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LNCE

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OKE

Oneok

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  • 27

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GXP

Great Plains Energy

$29.45

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  • 22

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MIC

Macquarie Infrastructure

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-0.75 (-1.17%)

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  • 22

    Feb

MIC

Macquarie Infrastructure

$63.62

-0.75 (-1.17%)

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  • 22

    Feb

CAKE

Cheesecake Factory

$46.22

0.61 (1.34%)

17:18
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  • 21

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UTX

United Technologies

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2.8 (2.21%)

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  • 21

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IAG

IAMGold

$5.86

0.07 (1.21%)

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  • 22

    Feb

CAKE

Cheesecake Factory

$46.22

0.61 (1.34%)

17:16
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  • 21

    Feb

P

Pandora

$4.87

-0.46 (-8.63%)

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CLVS

Clovis

$54.93

1.22 (2.27%)

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Clovis Oncology receives positive trend vote from CHMP for Rucaparib »

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