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KDMN

Kadmon

$3.91

0.29 (8.01%)

08:13
10/06/17
10/06
08:13
10/06/17
08:13

Kadmon receives orphan drug designation for KD025 for treatment of cGVHD

Kadmon announced that the U.S. Food and Drug Administration has granted orphan drug designation to KD025, the company's Rho-associated coiled-coil kinase inhibitor, for the treatment of chronic graft-versus-host disease, a serious complication following allogeneic bone marrow or stem cell transplantation. KD025 is being studied in an ongoing Phase 2 clinical trial in adults with steroid-dependent or steroid-refractory cGVHD and active disease. The dose-finding study includes 48 patients divided into three cohorts at different dose levels, enrolled sequentially following a safety assessment of each cohort. As previously reported, in a preliminary analysis of data from the lowest-dose cohort, KD025 200 mg QD demonstrated clinically meaningful responses, with no drug-related serious adverse events recorded.

  • 17

    Oct

KDMN Kadmon
$3.91

0.29 (8.01%)

03/14/17
PIPR
03/14/17
INITIATION
Target $7
PIPR
Overweight
Kadmon initiated with an Overweight at Piper Jaffray
Piper Jaffray analyst Edward Tenthoff started Kadmon Holdings with an Overweight rating and $7 price target.
03/16/17
WBBS
03/16/17
UPGRADE
WBBS
Hold
Kadmon upgraded to Hold from Sell at WBB Securities
WBB Securities analyst Stephen Brozak upgraded Kadmon to Hold.
07/11/17
PIPR
07/11/17
NO CHANGE
Target $7
PIPR
Overweight
Kadmon interim Phase II data 'impressive,' says Piper Jaffray
Piper Jaffray analyst Edward Tenthoff views Kadmon's preliminary Phase II data for KD025 in graft versus host disease patients as "impressive." Safety was "clean" and the primary endpoint was met, Tenthoff tells investors in a research note. He reiterates an Overweight rating on the shares with a $7 price target.
08/02/17
PIPR
08/02/17
NO CHANGE
Target $7
PIPR
Overweight
Imbruvica approval in graft versus host positive for Kadmon, says Piper Jaffray
After the FDA expanded the approval of AbbVie (ABBV) and Johnson & Johnson's (JNJ) Imbruvica for the treatment of adults with chronic graft versus host disease, or cGVHD, Piper Jaffray analyst Edward Tenthoff said he views the news as positive for Kadmon's KD025. Imbruvica is tough for patients to tolerate, said Tenthoff, who sees an opportunity for KD025 to more safely treat cGVHD patients. He keeps an Overweight rating and $7 price target on Kadmon shares.

TODAY'S FREE FLY STORIES

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General news
Breaking General news story  »

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ATRS

Antares Pharma

$2.18

0.06 (2.83%)

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  • 20

    Oct

18:55
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Conference/Events
Federal Reserve Chairperson delivers a lecture at NEC Dinner »

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SHIP

Seanergy Marine

$1.24

0.0199 (1.63%)

17:50
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Breaking Syndicate news story on Seanergy Marine »

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HLI

Houlihan Lokey

$41.56

0.18 (0.43%)

17:49
10/20/17
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Syndicate
Breaking Syndicate news story on Houlihan Lokey »

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  • 24

    Oct

GEO

Geo Group

$26.20

0.2 (0.77%)

17:48
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17:48
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Breaking Syndicate news story on Geo Group »

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  • 14

    Dec

DBVT

DBV Technologies

$48.07

0.92 (1.95%)

, AIMT

Aimmune

$25.66

-0.06 (-0.23%)

17:37
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17:37
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17:37
Hot Stocks
DBV sinks following peanut allergy trial miss, Aimmune soars »

Shares of DBV…

DBVT

DBV Technologies

$48.07

0.92 (1.95%)

AIMT

Aimmune

$25.66

-0.06 (-0.23%)

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  • 06

    Nov

KALV

KalVista

$11.26

1.99 (21.47%)

, DBVT

DBV Technologies

$48.07

0.92 (1.95%)

17:24
10/20/17
10/20
17:24
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17:24
Hot Stocks
On The Fly: After Hours Movers »

HIGHER: KalVista (KALV),…

KALV

KalVista

$11.26

1.99 (21.47%)

DBVT

DBV Technologies

$48.07

0.92 (1.95%)

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IPCI

Intellipharmaceutics

17:23
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10/20
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Breaking Hot Stocks news story on Intellipharmaceutics »

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DBVT

DBV Technologies

$48.07

0.92 (1.95%)

17:21
10/20/17
10/20
17:21
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17:21
Hot Stocks
DBV Technologies: PEPITES trial does not reach primary endpoint »

DBV Technologies…

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WFC

Wells Fargo

$54.92

1.17 (2.18%)

17:08
10/20/17
10/20
17:08
10/20/17
17:08
Periodicals
Regulator criticizes Wells Fargo over deceptive auto insurance program, NYT says »

The Office of the…

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  • 22

    Oct

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    Nov

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    Nov

  • 15

    Jan

ALIM

Alimera Sciences

17:01
10/20/17
10/20
17:01
10/20/17
17:01
Syndicate
Alimera Sciences to sell $25M in shares in an 'at the market offering' »

On October 20, Alimera…

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SYMC

Symantec

$32.66

0.33 (1.02%)

16:51
10/20/17
10/20
16:51
10/20/17
16:51
Syndicate
Breaking Syndicate news story on Symantec »

Symantec files to sell 1M…

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  • 01

    Nov

EBMT

Eagle Bancorp

$19.55

0.15 (0.77%)

16:44
10/20/17
10/20
16:44
10/20/17
16:44
Hot Stocks
Breaking Hot Stocks news story on Eagle Bancorp »

EJF Capital reports 7%…

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KALV

KalVista

$11.26

1.99 (21.47%)

16:43
10/20/17
10/20
16:43
10/20/17
16:43
Hot Stocks
Breaking Hot Stocks news story on KalVista »

Longwood Fund II reports…

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JAGX

Jaguar Health

$0.19

0.002 (1.08%)

16:41
10/20/17
10/20
16:41
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16:41
Syndicate
Breaking Syndicate news story on Jaguar Health »

Jaguar Health files to…

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TSLA

Tesla

$345.10

-6.71 (-1.91%)

16:40
10/20/17
10/20
16:40
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16:40
Hot Stocks
Tesla amends 'warehouse agreements' to increase commitments to $1.1B »

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  • 01

    Nov

  • 06

    Nov

SNV

Synovus

$47.30

0.54 (1.15%)

16:38
10/20/17
10/20
16:38
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16:38
Hot Stocks
Synovus CBO sells 10,000 common shares »

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  • 03

    Nov

  • 15

    Nov

GTXI

GTx

$7.92

0.1 (1.28%)

16:38
10/20/17
10/20
16:38
10/20/17
16:38
Syndicate
Breaking Syndicate news story on GTx »

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ASB

Associated Banc-Corp

$25.90

1.3 (5.28%)

, BKMU

BankMutual

$10.80

0.55 (5.37%)

16:36
10/20/17
10/20
16:36
10/20/17
16:36
Conference/Events
BankMutual to host special shareholder meeting »

Special Shareholder…

ASB

Associated Banc-Corp

$25.90

1.3 (5.28%)

BKMU

BankMutual

$10.80

0.55 (5.37%)

03/08/13
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  • 24

    Oct

CNXR

Connecture

$0.49

-0.01 (-2.00%)

16:35
10/20/17
10/20
16:35
10/20/17
16:35
Hot Stocks
Breaking Hot Stocks news story on Connecture »

Connecture trading…

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GE

General Electric

$23.83

0.25 (1.06%)

, PG

Procter & Gamble

$88.25

-3.34 (-3.65%)

16:31
10/20/17
10/20
16:31
10/20/17
16:31
General news
On The Fly: Top stock stories for Friday »

Stocks opened sharply…

GE

General Electric

$23.83

0.25 (1.06%)

PG

Procter & Gamble

$88.25

-3.34 (-3.65%)

CELG

Celgene

$121.33

-14.63 (-10.76%)

SNCR

Synchronoss

$11.39

-0.12 (-1.04%)

IL

Bought by SNCR

SKX

Skechers

$33.99

9.96 (41.45%)

PYPL

PayPal

$70.97

3.72 (5.53%)

NCR

NCR Corp.

$33.05

-4 (-10.80%)

LHO

LaSalle Hotel

$28.52

-1.94 (-6.37%)

03/08/13
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  • 20

    Oct

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    Oct

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    Oct

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    Oct

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    Nov

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    Nov

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    Nov

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    Nov

  • 30

    Nov

16:30
10/20/17
10/20
16:30
10/20/17
16:30
Options
Preliminary option volume of 22.9M today »

Preliminary option volume…

MKL

Markel

$1,078.23

14.88 (1.40%)

, SNC

State National

$21.05

0.02 (0.10%)

16:26
10/20/17
10/20
16:26
10/20/17
16:26
Conference/Events
State National to host special shareholder meeting »

Special Shareholder…

MKL

Markel

$1,078.23

14.88 (1.40%)

SNC

State National

$21.05

0.02 (0.10%)

03/08/13
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  • 24

    Oct

  • 26

    Oct

RYTM

Rhythm Pharmaceuticals

$23.08

-0.17 (-0.73%)

16:22
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10/20
16:22
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16:22
Hot Stocks
Breaking Hot Stocks news story on Rhythm Pharmaceuticals »

Orbimed Advisors reports…

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