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CAPR

Capricor Therapeutics

$2.81

-0.31 (-9.94%)

09:02
10/06/17
10/06
09:02
10/06/17
09:02

Capricor Therapeutics reports promising data on CAP-1002

Capricor Therapeutics, in a poster presentation at the Alliance for Regenerative Medicine's Cell and Gene Meeting on the Mesa, provided data which support the peripheral intravenous administration method the company plans to use in HOPE-2, its planned next clinical trial of its lead investigational product, CAP-1002, for the treatment of Duchenne muscular dystrophy. CAP-1002 consists of allogeneic cardiosphere-derived cells, whose mechanism of action is immunomodulatory and anti-fibrotic. CDCs have been shown to generate new muscle cells in preclinical models. In their poster presentation, Capricor and Cedars-Sinai Medical Center researchers reported that the IV administration of CDCs increases both exercise capacity and diaphragm function in a preclinical model of DMD, a rare and fatal genetic disorder with limited treatment options. The results also show that CDCs predominantly distribute to the lungs after injection and are cleared within three weeks. Dosing of more than 2.5 times the human equivalent dose proposed for the upcoming HOPE-2 trial was observed to be safe in these studies. The HOPE-2 Trial is being planned as a randomized, double-blind, placebo-controlled Phase II clinical trial that will evaluate repeat dosing of IV CAP-1002 in boys and young men with DMD. Subject to regulatory approval, Capricor plans to commence enrollment in HOPE-2 in the first quarter of 2018.

CAPR Capricor Therapeutics
$2.81

-0.31 (-9.94%)

02/13/17
RODM
02/13/17
INITIATION
Target $14
RODM
Buy
Capricor Therapeutics assumed with a Buy at Rodman & Renshaw
Rodman & Renshaw analyst Joseph Pantginis assumed coverage of Capricor Therapeutics with a Buy rating and $14 price target. The analyst believes the company has the potential to be a leader in cardiovascular regenerative medicine.
07/18/17
RODM
07/18/17
NO CHANGE
Target $2.15
RODM
Buy
FDA decision encouraging for Capricor Duchenne drug, says Rodman & Renshaw
Rodman & Renshaw analyst Joseph Pantginis notes that Capricor Therapeutics' CAP-1002 took an important regulatory step forward with the FDA granting Rare Pediatric Disease Designation for Duchenne muscular dystrophy. Should the positive CAP-1002 data continue to be positive and the therapy approved, Capricor could also be eligible for a Priority Review Voucher, or PRV, the analyst points out, adding that a key potential outcome to a PRV is not only an accelerated path to market, but the ability to sell the PRV for significant non-dilutive funding. Pantginis reiterates a Buy rating and $2.15 price target on the shares. In late morning trading, Capricor Therapeutics' stock has more than doubled to $1.44.
09/15/17
HCWC
09/15/17
NO CHANGE
Target $6.5
HCWC
Buy
Capricor Therapeutics price target raised to $6.50 from $2.15 at H.C. Wainwright
H.C. Wainwright analyst Joseph Pantginis raised his price target Capricor Therapeutics to $6.50 after increasing his projected chance of success for CAP-1002 in Duchenne muscular dystrophy to 15% from 5%. The analyst sees "significant" FDA visibility for the company's DMD program and believe catalysts next quarter could "reinvigorate interest in the shares." He keeps a Buy rating on Capricor.

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