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TRVN

Trevena

$2.37

-0.08 (-3.27%)

16:06
10/11/17
10/11
16:06
10/11/17
16:06

Trevena to restructure, halt investment in early stage research

Trevena announced an update to its strategy to focus its resources on the potential approval and commercialization of OLINVO in the United States. With this strategic re-positioning, the company is halting its investment in early stage research. The company intends to complete the ongoing Phase 1 trial of TRV250 for acute migraine, after which it will assess options for further development of this asset, as well as for its series of novel S1P modulators for neuropathic pain. As part of this plan, the company is reducing its workforce by approximately 30%, or 21 full time employees, predominantly from its research team. As part of this, Chief Scientific Officer Michael Lark, Ph.D., will depart the company in mid-December. The company estimates this reduction in force, along with other cost savings initiatives, will reduce cash expected to be used in operating activities over the next three calendar years by approximately $40M. The company also expects to incur a charge in Q4 of approximately $2.0M related to the reduction, of which approximately $1.7M is a cash charge relating primarily to severance costs and related expenses.

TRVN Trevena
$2.37

-0.08 (-3.27%)

02/21/17
JEFF
02/21/17
NO CHANGE
Target $11
JEFF
Buy
Jefferies sees hospital uptake for Trevena painkiller
After Trevena's oliceridine hit on two primary Phase III endpoints, Jefferies analyst Biren Amin says the debate is around the painkiller's commercial prospects with the stock 34% to $4.72 in midday trading. Oliceridine can be approved in late 2018 and the clinical profile overall should justify a health outcomes benefit, Amin tells investors in a research note. He highlights the drug's improved safety profile relative to morphine in today's data. The analyst keeps a Buy rating on Trevena with an $11 price target.
02/22/17
ROTH
02/22/17
NO CHANGE
Target $8.5
ROTH
Buy
Trevena price target lowered to $8.50 from $14.50 at Roth Capital
Roth Capital analyst Michael Higgins lowered his price target for Trevena to $8.50 from $14.50 after the company announced pivotal trial results with OLINVO from two trials in post-op bunionectomy and abdominoplasty patients. The analyst notes that his expectations for very strong efficacy results were met, but the stark reduction in adverse events versus morphine that he saw in the two Phase 2 did not materialize. He reiterates a Buy rating on the shares.
02/23/17
HCWC
02/23/17
NO CHANGE
Target $8
HCWC
Buy
Trevena price target lowered to $8 from $11 at H.C. Wainwright
H.C. Wainwright analyst Ed Arce lowered his price target for Trevena to $8 to reflect reduced expectations on Olinvo's commercial uptake following the Phase 3 readouts. The analyst does not believe commercial success is an "all-or-nothing" proposition, however, and keeps a Buy rating on the shares.
03/14/17
OPCO
03/14/17
NO CHANGE
Target $10
OPCO
Outperform
Trevena selloff overdone, says Oppenheimer
Oppenheimer analyst Derek Archila says that despite the company's mixed results relative to morphine, he believes the recent selloff is overdone and that Olinvo will be approved given its statistically significant results versus placebo. The analyst thinks Olinvo remains commercially viable given the trends on improved safety from the APOLLO studies, and should become an important option for patients most at risk for opioid-related adverse events. He reiterates an Outperform rating and $10 price target.

TODAY'S FREE FLY STORIES

TXN

Texas Instruments

$95.18

1.73 (1.85%)

13:10
10/23/17
10/23
13:10
10/23/17
13:10
Options
Texas Instruments calls active as shares see relative strength ahead of earnings »

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EEFT

Euronet

$98.71

1.93 (1.99%)

13:09
10/23/17
10/23
13:09
10/23/17
13:09
Conference/Events
Euronet management to meet with SunTrust »

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NVS

Novartis

$86.19

0.45 (0.52%)

, MCD

McDonald's

$164.22

-2.08 (-1.25%)

13:06
10/23/17
10/23
13:06
10/23/17
13:06
Earnings
Notable companies reporting before tomorrow's open »

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NVS

Novartis

$86.19

0.45 (0.52%)

MCD

McDonald's

$164.22

-2.08 (-1.25%)

MMM

3M

$222.12

0.8 (0.36%)

UTX

United Technologies

$120.63

-0.3 (-0.25%)

LLY

Eli Lilly

$87.68

0.45 (0.52%)

LMT

Lockheed Martin

$320.44

0.44 (0.14%)

CAT

Caterpillar

$132.06

0.7 (0.53%)

BIIB

Biogen

$338.10

-4.32 (-1.26%)

GM

General Motors

$45.37

-0.2389 (-0.52%)

SHW

Sherwin-Williams

$389.65

-0.055 (-0.01%)

INFY

Infosys

$14.90

0.34 (2.34%)

GLW

Corning

$30.36

0.295 (0.98%)

PCAR

Paccar

$74.92

1.15 (1.56%)

SWK

Stanley Black & Decker

$159.75

-0.37 (-0.23%)

FITB

Fifth Third

$28.60

0.32 (1.13%)

CNC

Centene

$97.59

1.09 (1.13%)

WAT

Waters

$188.63

0.49 (0.26%)

IPG

Interpublic Group

$20.62

-0.2641 (-1.26%)

WAB

Wabtec

$76.28

-0.59 (-0.77%)

HUBB

Hubbell

$121.43

-1.6355 (-1.33%)

JBLU

JetBlue

$20.35

0.01 (0.05%)

PII

Polaris Industries

$106.55

0.09 (0.08%)

GPK

Graphic Packaging

$14.30

0.02 (0.14%)

R

Ryder

$82.98

-0.67 (-0.80%)

CVLT

Commvault

$58.55

0.5 (0.86%)

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WHR

Whirlpool

$182.85

0.39 (0.21%)

, ARNC

Arconic

$25.05

-2.12 (-7.80%)

13:05
10/23/17
10/23
13:05
10/23/17
13:05
Earnings
Notable companies reporting after market close »

Notable companies…

WHR

Whirlpool

$182.85

0.39 (0.21%)

ARNC

Arconic

$25.05

-2.12 (-7.80%)

ZION

Zions Bancorp

$46.76

0.71 (1.54%)

CR

Crane

$84.02

-0.09 (-0.11%)

OI

Owens-Illinois

$25.35

-0.24 (-0.94%)

RMBS

Rambus

$13.70

0.12 (0.88%)

03/08/13
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    Dec

COG

Cabot Oil & Gas

$25.39

-0.14 (-0.55%)

13:05
10/23/17
10/23
13:05
10/23/17
13:05
Options
Cabot Oil & Gas call volume above normal and directionally bullish »

Bullish option flow…

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13:05
10/23/17
10/23
13:05
10/23/17
13:05
General news
Treasury Action: the markets are quiet as a wait and see stance prevails »

Treasury Action: the…

NKE

Nike

$53.79

0.73 (1.38%)

12:55
10/23/17
10/23
12:55
10/23/17
12:55
Options
Nike put volume heavy and directionally bearish »

Bearish flow noted in…

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  • 25

    Oct

ADP

ADP

$115.93

1.31 (1.14%)

12:54
10/23/17
10/23
12:54
10/23/17
12:54
Hot Stocks
ADP 'strongly disagrees' with Glass Lewis' recommendation on director election »

ADP issued the following…

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  • 02

    Nov

UTX

United Technologies

$120.73

-0.205 (-0.17%)

12:46
10/23/17
10/23
12:46
10/23/17
12:46
Technical Analysis
Technical Earnings Preview: United Technologies in uptrend ahead of news »

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FCX

Freeport McMoRan

$14.78

-0.049 (-0.33%)

12:45
10/23/17
10/23
12:45
10/23/17
12:45
Options
Freeport McMoRan call volume above normal and directionally bullish »

Bullish option flow…

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  • 25

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AGN

Allergan

$189.61

1.33 (0.71%)

12:45
10/23/17
10/23
12:45
10/23/17
12:45
Periodicals
Allergan has weak balance sheet after large buybacks, WSJ's Grant says »

Allergan squandered the…

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SSYS

Stratasys

$23.21

2.26 (10.79%)

12:37
10/23/17
10/23
12:37
10/23/17
12:37
Hot Stocks
Stratasys announces NYU study on treating kidney issues with 3D technology »

Stratasys announced a new…

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  • 14

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TAL

TAL Education

$34.05

-0.865 (-2.48%)

12:35
10/23/17
10/23
12:35
10/23/17
12:35
Options
Tal Education Group put volume heavy and directionally bearish »

Bearish flow noted in Tal…

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  • 26

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LGL

LGL Group

$5.66

0.1 (1.80%)

12:32
10/23/17
10/23
12:32
10/23/17
12:32
Hot Stocks
LGL Group reports extension of rights offering expiration to November 13 »

The LGL Group announced…

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BBW

Build-A-Bear

$8.15

-0.1 (-1.21%)

12:32
10/23/17
10/23
12:32
10/23/17
12:32
Conference/Events
Build-A-Bear management to meet with Jefferies »

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SYBX

Synlogic

$15.01

-1.46 (-8.86%)

12:28
10/23/17
10/23
12:28
10/23/17
12:28
Conference/Events
Synlogic management to meet with Jefferies »

Meeting to be held in San…

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  • 26

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ROIC

Retail Opportunity

$18.76

-0.3 (-1.57%)

12:26
10/23/17
10/23
12:26
10/23/17
12:26
Conference/Events
Retail Opportunity management to meet with Jefferies »

Meetings to be held n…

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MCD

McDonald's

$164.42

-1.88 (-1.13%)

12:26
10/23/17
10/23
12:26
10/23/17
12:26
Technical Analysis
Technical Earnings Preview: McDonald's testing support ahead of earnings »

Price has been within a…

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  • 24

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XOM

Exxon Mobil

$83.21

0.1 (0.12%)

12:20
10/23/17
10/23
12:20
10/23/17
12:20
Options
11.7K Exxon Mobile Jan 82.5 - Mar 87.5 call spreads bought for $1.40 »

11.7K Exxon Mobile Jan…

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  • 27

    Oct

$NSD

NASDAQ Market Internals

12:17
10/23/17
10/23
12:17
10/23/17
12:17
Technical Analysis
NASDAQ market internals summary »

Volume is average for…

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$NYE

NYSE Market Internals

12:16
10/23/17
10/23
12:16
10/23/17
12:16
Technical Analysis
NYSE market internals summary »

Volume is below average…

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12:15
10/23/17
10/23
12:15
10/23/17
12:15
General news
Treasury Option Action: some "call fly" demand »

Treasury Option Action:…

SAGE

Sage Therapeutics

$63.50

0.58 (0.92%)

12:10
10/23/17
10/23
12:10
10/23/17
12:10
Options
Sizable ratio spread in Sage Therapeutics »

Sizable ratio spread in…

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VLKAY

Volkswagen

$35.00

-0.25 (-0.71%)

12:08
10/23/17
10/23
12:08
10/23/17
12:08
Periodicals
Volkswagen receives approval from U.S regulators for SUV fix, Reuters says »

U.S and California…

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RMBS

Rambus

$13.70

0.12 (0.88%)

12:05
10/23/17
10/23
12:05
10/23/17
12:05
Technical Analysis
Technical Earnings Preview: Rambus in bullish price channel ahead of news »

The shares have been…

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