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MGEN

Miragen Therapeutics

$9.21

-0.18 (-1.92%)

07:08
10/13/17
10/13
07:08
10/13/17
07:08

Miragen Therapeutics says new MRG-106 data suggests 'positive impact'

miRagen Therapeutics announced new interim results from its ongoing Phase 1 clinical trial evaluating the safety, efficacy and pharmacokinetics of MRG-106 in patients with the mycosis fungoides, or MF, form of cutaneous T-cell lymphoma, or CTCL. The data is being presented at the European Organisation for Research and Treatment of Cancer, or EORTC, Cutaneous Lymphoma Task Force Meeting in London, United Kingdom, by Christiane Querfeld, M.D., Ph.D., Chief of the Division of Dermatology, and Director, Cutaneous Lymphoma Program at the City of Hope in Duarte, California. "We are encouraged by the new MRG-106 Phase 1 data, as we observed that 96% of patients treated systemically experienced improvement in total skin disease at all dose levels evaluated," said miRagen President and CEO William S. Marshall, Ph.D. "These findings suggest that MRG-106 has the potential to offer meaningful benefit to patients with CTCL. We are making what we believe to be important progress for patients in our MRG-106 Phase 1 clinical trial, and we were pleased to share these new data with the medical community." The MRG-106 Phase 1 trial consists of two parts. In the first part, patients were treated with 75 mg injections of MRG-106 directly into a specific lesion. These data, which showed a decrease in lesion size for all injected lesions, have been previously presented. The second part employed a multiple dose-escalation design to evaluate 300 mg, 600 mg or 900 mg subcutaneous or intravenous administrations of MRG-106. The newest results to be reported at EORTC include observations from four additional patients as well as longer term dosing data for existing patients who have continued on the trial.

MGEN Miragen Therapeutics
$9.21

-0.18 (-1.92%)

02/21/17
WEDB
02/21/17
INITIATION
Target $19
WEDB
Outperform
Miragen Therapeutics initiated with an Outperform at Wedbush
Wedbush analyst Liana Moussatos initiated Miragen Therapeutics with an Outperform and a $19 price target.
06/01/17
COWN
06/01/17
INITIATION
COWN
Outperform
Miragen Therapeutics initiated with an Outperform at Cowen
Cowen analyst Ritu Baral initiated Miragen Therapeutics with an Outperform saying it has a promising microRNA platform technology with two candidates MRG-106 for CTCL and MRG-201 for fibrotic conditions. He believes the ongoing/imminent CTCL and keloid clinical studies should generate value creating data catalysts regularly over the next 18 months.

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IPCI

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DBVT

DBV Technologies

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WFC

Wells Fargo

$54.92

1.17 (2.18%)

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ALIM

Alimera Sciences

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SYMC

Symantec

$32.66

0.33 (1.02%)

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EBMT

Eagle Bancorp

$19.55

0.15 (0.77%)

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KALV

KalVista

$11.26

1.99 (21.47%)

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JAGX

Jaguar Health

$0.19

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TSLA

Tesla

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GTXI

GTx

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ASB

Associated Banc-Corp

$25.90

1.3 (5.28%)

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BankMutual

$10.80

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CNXR

Connecture

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GE

General Electric

$23.83

0.25 (1.06%)

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IL

Bought by SNCR

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MKL

Markel

$1,078.23

14.88 (1.40%)

, SNC

State National

$21.05

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RYTM

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