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MGEN

Miragen Therapeutics

$9.21

-0.18 (-1.92%)

07:08
10/13/17
10/13
07:08
10/13/17
07:08

Miragen Therapeutics says new MRG-106 data suggests 'positive impact'

miRagen Therapeutics announced new interim results from its ongoing Phase 1 clinical trial evaluating the safety, efficacy and pharmacokinetics of MRG-106 in patients with the mycosis fungoides, or MF, form of cutaneous T-cell lymphoma, or CTCL. The data is being presented at the European Organisation for Research and Treatment of Cancer, or EORTC, Cutaneous Lymphoma Task Force Meeting in London, United Kingdom, by Christiane Querfeld, M.D., Ph.D., Chief of the Division of Dermatology, and Director, Cutaneous Lymphoma Program at the City of Hope in Duarte, California. "We are encouraged by the new MRG-106 Phase 1 data, as we observed that 96% of patients treated systemically experienced improvement in total skin disease at all dose levels evaluated," said miRagen President and CEO William S. Marshall, Ph.D. "These findings suggest that MRG-106 has the potential to offer meaningful benefit to patients with CTCL. We are making what we believe to be important progress for patients in our MRG-106 Phase 1 clinical trial, and we were pleased to share these new data with the medical community." The MRG-106 Phase 1 trial consists of two parts. In the first part, patients were treated with 75 mg injections of MRG-106 directly into a specific lesion. These data, which showed a decrease in lesion size for all injected lesions, have been previously presented. The second part employed a multiple dose-escalation design to evaluate 300 mg, 600 mg or 900 mg subcutaneous or intravenous administrations of MRG-106. The newest results to be reported at EORTC include observations from four additional patients as well as longer term dosing data for existing patients who have continued on the trial.

MGEN Miragen Therapeutics
$9.21

-0.18 (-1.92%)

02/21/17
WEDB
02/21/17
INITIATION
Target $19
WEDB
Outperform
Miragen Therapeutics initiated with an Outperform at Wedbush
Wedbush analyst Liana Moussatos initiated Miragen Therapeutics with an Outperform and a $19 price target.
06/01/17
COWN
06/01/17
INITIATION
COWN
Outperform
Miragen Therapeutics initiated with an Outperform at Cowen
Cowen analyst Ritu Baral initiated Miragen Therapeutics with an Outperform saying it has a promising microRNA platform technology with two candidates MRG-106 for CTCL and MRG-201 for fibrotic conditions. He believes the ongoing/imminent CTCL and keloid clinical studies should generate value creating data catalysts regularly over the next 18 months.

TODAY'S FREE FLY STORIES

CLI

Mack-Cali Realty

$18.33

-0.25 (-1.35%)

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CLI

Mack-Cali Realty

$18.33

-0.25 (-1.35%)

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MIC

Macquarie Infrastructure

$63.62

-0.75 (-1.17%)

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ILG

ILG

$32.31

0.12 (0.37%)

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TGB

Taseko Mines

$1.76

0.03 (1.73%)

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BAND

Bandwidth

$24.09

0.18 (0.75%)

17:26
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BAND

Bandwidth

$24.09

0.18 (0.75%)

17:25
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Bandwidth sees Q1 adjusted EPS 7c-10c, may not compare to consensus (6c) »

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  • 21

    Feb

SM

SM Energy

$21.30

-0.54 (-2.47%)

17:25
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SM Energy sees Q1 production 9.5-10.0 MMBoe »

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  • 22

    Feb

BAND

Bandwidth

$24.09

0.18 (0.75%)

17:24
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Bandwidth reports Q4 adjusted EPS 9c, consensus 0c »

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  • 21

    Feb

SM

SM Energy

$21.30

-0.54 (-2.47%)

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SM Energy sees 2018 production 42-46 MMBoe, 41% oil »

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  • 22

    Feb

P

Pandora

$4.87

-0.46 (-8.63%)

17:24
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Earnings
Pandora sees Q1 revenue $295M-$305M, consensus $322.87M »

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SM

SM Energy

$21.30

-0.54 (-2.47%)

17:23
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Earnings
SM Energy reports Q4 adjusted EPS (8c), consensus (14c) »

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  • 22

    Feb

P

Pandora

$4.87

-0.46 (-8.63%)

17:22
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Pandora expects FY18 top-line growth to come from subscription business »

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LNCE

Snyder's-Lance

$49.90

-0.1 (-0.20%)

17:22
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Snyder's-Lance initiates recall for a limited amount of Glazed Walnuts product »

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OKE

Oneok

$56.10

-0.92 (-1.61%)

17:20
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ONEOK to invest $2.3B for additional NGL, natural gas infrastructure »

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  • 27

    Feb

GXP

Great Plains Energy

$29.45

-0.33 (-1.11%)

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  • 22

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MIC

Macquarie Infrastructure

$63.62

-0.75 (-1.17%)

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MIC

Macquarie Infrastructure

$63.62

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Earnings
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  • 22

    Feb

CAKE

Cheesecake Factory

$46.22

0.61 (1.34%)

17:18
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Earnings
Cheesecake Factory sees FY18 EPS $2.64-$2.80, consensus $2.73 »

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  • 21

    Feb

UTX

United Technologies

$129.26

2.8 (2.21%)

17:17
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United Technologies awarded $2.5B U.S. Defense Department contract »

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  • 21

    Feb

IAG

IAMGold

$5.86

0.07 (1.21%)

17:17
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IAMGold sees 2018 attributable gold production 850K-900K oz. »

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  • 22

    Feb

CAKE

Cheesecake Factory

$46.22

0.61 (1.34%)

17:16
02/21/18
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Earnings
Cheesecake Factory sees Q1 EPS 66c-70c, consensus 68c »

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  • 21

    Feb

P

Pandora

$4.87

-0.46 (-8.63%)

17:16
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Breaking Hot Stocks news story on Pandora »

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CLVS

Clovis

$54.93

1.22 (2.27%)

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Clovis Oncology receives positive trend vote from CHMP for Rucaparib »

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  • 26

    Feb

HBM

Hudbay Minerals

$8.15

0.1 (1.24%)

17:10
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Hudbay Minerals sees FY18 production outlook unchanged »

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  • 22

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