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ITEK

Inotek Pharmaceuticals

$2.95

0.18 (6.50%)

09:30
10/13/17
10/13
09:30
10/13/17
09:30

Inotek jumps after detailing Rocket's near-term clinical catalysts

Inotek Pharmaceuticals last night announced the filing with the SEC of the company's preliminary proxy statement in connection with the previously announced proposed combination with Rocket Pharmaceuticals. "We believe the proposed merger with Rocket provides an attractive opportunity for our shareholders," said David Southwell, CEO of Inotek. "Rocket has several near-term clinical and proof of concept catalysts, a well-funded operation and a management team with rare disease and gene therapy leadership expertise." Inotek listted among its key Rocket Pharmaceuticals investment decisions, "A fifth undisclosed AAV-based gene therapy program is expected to enter the clinic next year and has demonstrated encouraging histological correction of the disease phenotype. This exciting program targets a monogenic pediatric disease with early mortality and represents the first gene therapy being developed for this large class of indications." Gaurav Shah, CEO of Rocket, said in the press release, "Preliminary results from our ongoing Phase 1/2 trial in Fanconi Anemia are encouraging, and we are seeing early signs of in vivo engraftment and hematological stabilization suggesting the potential for complete recovery of these patients back to normal blood counts. With this merger, we look forward to accelerating the advancement of our four other programs in LAD-I, PKD, IMO and our AAV-based therapy, into the clinic." Shares of Inotek are up 19% to $3.50 in early trading.

ITEK Inotek Pharmaceuticals
$2.95

0.18 (6.50%)

01/03/17
PIPR
01/03/17
DOWNGRADE
PIPR
Neutral
Inotek Pharmaceuticals downgraded to Neutral from Overweight at Piper Jaffray
Piper Jaffray analyst Joshua Schimmer downgraded Inotek Pharmaceuticals to Neutral saying that while timolol appeared active in the Phase III MATrX-1 study, only the highest dose of tranodenoson came close but still missed the primary endpoint. The analyst wants to see "clearer path towards clinical, regulatory and commercial success" before recommending the shares. He cut his price target for the shares to $3 from $24. Inotek is down 63%, or $3.85, to $2.25 in pre-market trading.
01/04/17
ROTH
01/04/17
NO CHANGE
Target $3
ROTH
Buy
Inotek Pharmaceuticals price target lowered to $3 from $10 at Roth Capital
Roth Capital analyst Sa'ar Yaniv lowered his price target for Inotek Pharmaceuticals to $3 from $10 after its MATrX-1 failed to demonstrate statistically significant decrease in intraocular pressure in glaucoma patients compared with placebo. Despite the "disappointing setback," the analyst believes that value remains in the trabodenoson franchise. He reiterates a Buy rating on the shares.
07/11/17
HCWC
07/11/17
DOWNGRADE
HCWC
Neutral
Inotek Pharmaceuticals downgraded to Neutral from Buy at H.C. Wainwright
H.C. Wainwright analyst Corey Davis downgraded Inotek Pharmaceuticals to Neutral after the company decided not to take trabodenoson forward into Phase 3 testing in glaucoma. The most likely outcome of the company's strategic review is a reverse merger with a private company to put its $109M in cash to work with new assets, Davis tells investors in a research note. He cut his price target for the shares to $2 from $7.
07/12/17
ADAM
07/12/17
DOWNGRADE
ADAM
Hold
Inotek Pharmaceuticals downgraded to Hold from Buy at Canaccord
Canaccord analyst Dewey Steadman downgraded Inotek Pharmaceuticals to Hold with a $1 price target following disappointing top-line data for its Phase 2 fixed-dose combination trial which did not demonstrate any benefit in any of the arms tested.

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