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ALXN

Alexion

$135.20

-3.82 (-2.75%)

05:25
10/24/17
10/24
05:25
10/24/17
05:25

Alexion announces FDA approval of Soliris

Alexion Pharmaceuticals announced that the FDA has approved Soliris as a treatment for adult patients with generalized myasthenia gravis, or gMG, who are anti-acetylcholine receptor, or AchR, antibody-positive. In the Phase 3 REGAIN study and its ongoing open-label extension study, Soliris demonstrated treatment benefits for patients with anti-AchR antibody-positive gMG who had previously failed immunosuppressive treatment and continued to suffer from significant unresolved disease symptoms, which can include difficulties seeing, walking, talking, swallowing and breathing. These patients are at an increased risk of disease exacerbations and crises that may require hospitalization and intensive care and may be life-threatening. These patients represent approximately 5%-10% of all patients with MG.

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    Nov

ALXN Alexion
$135.20

-3.82 (-2.75%)

10/23/17
PIPR
10/23/17
INITIATION
Target $170
PIPR
Overweight
Alexion assumed with an Overweight at Piper Jaffray
Piper Jaffray analyst Christopher Raymond assumed coverage of Alexion Pharmaceuticals with an Overweight rating and $170 price target. The rating is unchanged and the price target is raised from $168. The analyst believes the base business has been stabilized and expects "meaningful progress" into 2018 as management executes on its strategic refocusing.
10/13/17
LEHM
10/13/17
NO CHANGE
LEHM
Barclays cautious on Merck and Regeneron into Q3 results
In a research note previewing the Q3 earnings reports for U.S. Biopharmaceuticals, Barclays analyst Geoff Meacham says he's positive on positive on Amgen (AMGN) and Alexion Pharmaceuticals (ALXN), cautious on Merck (MRK), and bearish on Regeneron (REGN). The analyst made a host of price target changes, including raising Amgen's target to $190 from $180, AbbVie's (ABBV) target to $90 from $68 and Bristol-Myers' target to $65 from $58.
09/25/17
LEER
09/25/17
NO CHANGE
Target $182
LEER
Outperform
Alexion Soliris to continue dominance through 2020, says Leerink
Leerink analyst Geoffrey Porges notes that Alexion's Soliris was the first complement inhibitor to be approved by the FDA or EMA and has remained the only terminal complement inhibitor on the market. While some competitors have advanced to pivotal trials, and have established safety and efficacy, none have shown themselves to be superior to Soliris in efficacy, nor more convenient than ALXN1210, he adds. The analyst believes the development timelines for these new entrants suggest that Soliris will continue its dominance of the category through 2020, and even then will face its biggest challenge from Alexion's own next generation complement inhibitor, ALXN1210. Porges reiterates an Outperform rating and $182 price target on the shares.
09/14/17
RBCM
09/14/17
INITIATION
Target $161
RBCM
Outperform
Alexion initiated with an Outperform at RBC Capital
RBC Capital analyst Kennen MacKay initiated Alexion with an Outperform and a $161 price target saying shares are undervalued following management changes and restructuring. He said Soliris market dynamics suggest continued future growth despite PNH Patient competition.

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