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ONCE

Spark Therapeutics

$72.25

0.49 (0.68%)

17:06
11/10/17
11/10
17:06
11/10/17
17:06

Spark Therapeutics: Follow-up Luxturna data shows no significant change

Spark Therapeutics announced new three-year follow-up data from the continuing Phase 3 trial of LUXTURNA, an investigational, potential one-time gene therapy for the treatment of patients with vision loss due to confirmed biallelic RPE65-mediated inherited retinal disease. These data were presented at the American Academy of Ophthalmology Retina Subspecialty Day by Albert M. Maguire, M.D., a principal investigator of the Phase 3 clinical trial, professor of ophthalmology at the Scheie Eye Institute at the University of Pennsylvania's Perelman School of Medicine and attending physician in the Division of Pediatric Ophthalmology at Children's Hospital of Philadelphia. "These data provide additional support information on the efficacy, durability and safety of investigational LUXTURNA, showing no statistically significant change in the primary endpoint from the initial gain in functional vision at the three-year time point for the original intervention group and at the two-year time point for the original control group after crossover," said Katherine High, M.D., president and head of Research and Development at Spark Therapeutics. "We believe the data from these participants further support the positive benefit-risk profile of investigational LUXTURNA for patients with vision loss due to confirmed biallelic RPE65-mediated IRD."

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ONCE Spark Therapeutics
$72.25

0.49 (0.68%)

10/16/17
RHCO
10/16/17
NO CHANGE
Target $101
RHCO
Buy
Spark Therapeutics price target raised to $101 from $95 at SunTrust
SunTrust analyst Edward Nash raised his price target on Spark Therapeutics to $101, citing the latest FDA AdCom support for Luxturna. The analyst says the positive recommendation and the liberal stance taken by the AdCom on labeling increases Luxturna probability of success, maintaining a Buy rating on Spark Therapeutics stock.
10/16/17
HCWC
10/16/17
NO CHANGE
Target $30
HCWC
Buy
Abeona Therapeutics price target raised to $30 from $20 at H.C. Wainwright
H.C. Wainwright analyst Raghuram Selvaraju raised his price target for Abeona Therapeutics (ABEO) to $30 saying the company's R&D day showcased its pipeline value. Further, the FDA panel vote for Spark Therapeutics' (ONCE) Luxturna indicates a positive gene therapy outlook, the analyst tells investors in a research note. He reiterates a Buy rating on Abeona.
10/13/17
CANT
10/13/17
NO CHANGE
Target $105
CANT
Overweight
Spark Therapeutics price target raised to $105 from $94 at Cantor Fitzgerald
Cantor Fitzgerald analyst Elemer Piros raised his price target for Spark Therapeutics to $105 following the unanimous advisory committee recommendation to approve Luxturna for the treatment of biallelic RPE65 mutation-associated retinal dystrophy. The analyst expects expedited approval for Luxturna well before its January 12, 2018, FDA action date. He keeps an Overweight rating on Spark Therapeutics.
10/13/17
STFL
10/13/17
NO CHANGE
Target $101
STFL
Buy
Spark Therapeutics price target raised to $101 from $92 at Stifel
Stifel analyst Stephen Willey said the vote of an FDA advisory committee in favor of the overall benefit-risk profile of Spark Therapeutics' voretigene neparvovec was "precisely in-line" with both his and the consensus expectation and he now expects the pricing/reimbursement debate to accelerate ahead of the January PDUFA date for the treatment. The analyst, who has adjusted both his expectations for pricing and some patient-related factors, raised his price target on Spark shares to $101 from $92 and keeps a Buy rating on the stock.

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