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TCON

TRACON Pharmaceuticals

16:06
11/29/17
11/29
16:06
11/29/17
16:06

TRACON Pharmaceuticals doses 1st patient in Phase 1b study of TRC105 with Opdivo

TRACON Pharmaceuticals announced that the first patient has been dosed in its Phase 1b clinical trial of TRC105 in combination with Opdivo in patients with non-small cell lung cancer. The primary objectives of the Phase 1b study are to assess the safety of TRC105 when given with Opdivo, determine its recommended Phase 2 dose with Opdivo and evaluate the response rate. The trial incorporates tumor biopsy testing to correlate tumor myeloid cell infiltration with response, in order to allow for potential biomarker-directed therapy of lung cancer patients.

TCON TRACON Pharmaceuticals

12/21/16
JEFF
12/21/16
INITIATION
Target $41
JEFF
Buy
TRACON Pharmaceuticals initiated with a Buy at Jefferies
Jefferies analyst Brian Abrahams started TRACON Pharmaceuticals with a Buy rating and $41 price target. The company's TRC105 has demonstrated activity signals across multiple solid tumors that should be confirmed in 2017 readouts, the analyst contends.
01/03/17
WELS
01/03/17
DOWNGRADE
WELS
Market Perform
TRACON Pharmaceuticals downgraded to Market Perform at Wells Fargo
06/13/17
STFL
06/13/17
NO CHANGE
STFL
TRACON price target lowered to $6 from $14 at Stifel
Stifel analyst Thomas Shrader lowered his price target on TRACON (TCON) after Acceleron (ALRN) announced results from its Phase II study of dalantercept. The analyst says that TRACON's drug targets the same pathway as Acceleron's treatment, although "there are important differences" between the drugs and Sharder still thinks that TRACON's drug can provide "tumor killing" benefits. However, the analyst reduced TRC105's probability of success in RCC and HCC to 50%. But the analyst keeps a Buy rating on the stock.

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