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SNY

Sanofi

$43.17

-0.34 (-0.78%)

08:06
12/07/17
12/07
08:06
12/07/17
08:06

Sanofi explores combination treatments for multiple myeloma in new trials

Sanofi has launched two new late-stage clinical studies to determine if an investigational biologic called isatuximab, when used in combination with other commonly used cancer treatments, might be an effective treatment option for certain people with multiple myeloma, a rare blood cancer related to lymphoma and leukemia. Isatuximab is an investigational anti-CD38 monoclonal antibody being studied for the treatment of patients with relapsed and previously untreated multiple myeloma. IKEMA study is a 325-patient randomized, open-label, global multicenter Phase 3 trial that will compare isatuximab in combination with carfilzomib and dexamethasone against carfilzomib and dexamethasone in patients with relapsed and refractory multiple myeloma that have previously been treated with one-to-three lines of therapy. IMROZ study is a 425-patient randomized, open-label, global multicenter Phase 3 trial that will compare isatuximab in combination with bortezomib, lenalidomide and dexamethasone against bortezomib, lenalidomide and dexamethasone in newly diagnosed multiple myeloma patients not eligible for transplant. Isatuximab has been granted orphan designation in the U.S. and European Union. In December 2016, Sanofi started an additional Phase 3 study, comparing isatuximab in combination with pomalidomide and dexamethasone against pomalidomide and dexamethasone in patients with relapsed and refractory multiple myeloma. The development program for isatuximab will now total three Phase 3 studies.

  • 18

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  • 25

    Mar

SNY Sanofi
$43.17

-0.34 (-0.78%)

11/15/17
LEHM
11/15/17
UPGRADE
LEHM
Equal Weight
Sanofi upgraded to Equal Weight from Underweight at Barclays
Barclays upgraded Sanofi to Equal Weight from Underweight saying valuation is back to more reasonable levels.
11/16/17
EVER
11/16/17
NO CHANGE
Target $445
EVER
Outperform
Regeneron price target lowered to $445 from $605 at Evercore ISI
Evercore ISI lowered its price target for Regeneron (REGN) to $445 from $605 given meaningful competitive threat to Eylea. For every dollar of U.S. Eylea sales lost to competition, Regeneron has to make up for it with two times as much revenue from the Sanofi (SNY) JV, it adds. The firm has an Outperform rating on Regeneron's shares.
12/01/17
MSCO
12/01/17
DOWNGRADE
MSCO
Underweight
Sanofi downgraded to Underweight from Overweight at Morgan Stanley
12/06/17
BOFA
12/06/17
DOWNGRADE
BOFA
Neutral
Sanofi downgraded to Neutral from Buy at BofA/Merrill
BofA/Merrill analyst Graham Perry downgraded Sanofi to Neutral citing valuation and lack of earnings momentum into 2018.

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LYV

Live Nation

$48.15

-0.53 (-1.09%)

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XLE

Energy Select Sector SPDR

$72.63

0.21 (0.29%)

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Utilities SPDR

$54.50

0.25 (0.46%)

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Week ending ETF Scorecard: Consumer Staples outperforms, Energy skids »

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SPDR Gold Trust

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GLD

SPDR Gold Trust

$112.12

1.01 (0.91%)

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SPDR Gold Trust holdings fall to 772.24MT from 773.41MT »

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GDOT

Green Dot

$85.04

0.37 (0.44%)

17:30
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Green Dot exec Dent sells 7,754 common shares »

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  • 25

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SMSI

Smith Micro

$2.49

-0.01 (-0.40%)

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Breaking Syndicate news story on Smith Micro »

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NDRA

ENDRA Life Sciences

$2.70

0.2 (8.00%)

17:14
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Breaking Syndicate news story on ENDRA Life Sciences »

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BA

Boeing

$346.44

0.55 (0.16%)

17:10
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Boeing awarded $152.5M U.S. Navy contract »

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BA

Boeing

$346.44

0.55 (0.16%)

17:09
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Boeing awarded $217M Defense Department contract »

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LLL

L3 Technologies

$210.37

0.56 (0.27%)

17:08
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Hot Stocks
L3 Technologies awarded $240M Defense Department contract »

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HSGX

Histogenics

$2.65

-0.05 (-1.85%)

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Syndicate
Breaking Syndicate news story on Histogenics »

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PLD

Prologis

$67.45

1.79 (2.73%)

, DCT

DCT Industrial

$68.77

1.805 (2.70%)

16:58
08/17/18
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Conference/Events
DCT Industrial to host special shareholder meeting »

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PLD

Prologis

$67.45

1.79 (2.73%)

DCT

DCT Industrial

$68.77

1.805 (2.70%)

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WLK

Westlake Chemical

$95.61

-1.33 (-1.37%)

16:56
08/17/18
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Hot Stocks
Westlake Chemical expands share repurchase program by $150M »

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SM

SM Energy

$27.38

0.17 (0.62%)

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SM Energy analyst commentary at MUFG »

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  • 19

    Aug

PENN

Penn National

$33.04

0.86 (2.67%)

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Penn National CEO acquires 100,000 common shares »

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FB

Facebook

$173.78

-0.98 (-0.56%)

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Periodicals
U.S. wants Facebook to help wiretap Messenger for criminal probe, Reuters says »

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WLK

Westlake Chemical

$95.61

-1.33 (-1.37%)

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Westlake Chemical raises quarterly dividend 19% to 25c per share »

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EAST

Eastside Distilling

$7.40

-0.01 (-0.13%)

16:45
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Breaking Syndicate news story on Eastside Distilling »

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LOV

Spark Networks

$12.80

-0.095 (-0.74%)

16:44
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Syndicate
Spark Networks files to sell 515,416 ordinary shares for holders »

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AHPA

Avista Healthcare Public Acquisition Corp.

$10.12

(0.00%)

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Avista Healthcare Public Acquisition Corp., Organogenesis announce combination »

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TCF

TCF Financial

$25.84

0.17 (0.66%)

16:41
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Hot Stocks
TCF Financial COO sells 77,725 common shares »

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LGF.A

Lionsgate

$22.95

-0.11 (-0.48%)

16:38
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Recommendations
Lionsgate analyst commentary at Barrington »

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  • 11

    Sep

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General news
Breaking General news story  »

Moody's cuts Turkey…

MSL

MidSouth Bancorp

$14.90

0.1 (0.68%)

16:32
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MidSouth Bancorp says 'will carefully review' letter sent by Jacobs Asset Mgt. »

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EME

EMCOR

$77.96

1.005 (1.31%)

16:31
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Hot Stocks
Emcor CEO sells 23,434 common shares »

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16:30
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Options
Preliminary option volume of 22.3M today »

Preliminary option volume…

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