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AGIO

Agios Pharmaceuticals

$58.12

3.99 (7.37%)

07:32
12/26/17
12/26
07:32
12/26/17
07:32

Agios Pharmaceuticals submits new FDA application for Ivosidenib

Agios Pharmaceuticals announced that it has submitted a New Drug Application to the U.S. Food and Drug Administration for ivosidenib, an investigational oral treatment for patients with relapsed or refractory acute myeloid leukemia and an isocitrate dehydrogenase-1 mutation. Agios has requested priority review for the application, which, if granted, could result in a six-month review process. The NDA is supported by data from the ongoing Phase 1 dose-escalation and expansion study of ivosidenib in patients with advanced hematologic malignancies and an IDH1 mutation. Ivosidenib is wholly owned by Agios. The FDA has a 60-day filing review period to determine whether the NDA is complete and acceptable for filing.

AGIO Agios Pharmaceuticals
$58.12

3.99 (7.37%)

08/02/17
08/02/17
UPGRADE
Target $80

Outperform
Agios Pharmaceuticals upgraded to Outperform at Leerink
As previously reported, Leerink analyst Michael Schmidt upgraded Agios Pharmaceuticals to Outperform from Market Perform based on his higher-level conviction regarding the commercial opportunity for its IDH inhibitors Idhifa and ivosidenib in acute myeloid leukemia following Idhifa FDA-approval and his recent checks indicating a high degree of enthusiasm for these agents in the physician community pointing to potential good initial uptake. The analyst also raised his price target on the shares to $80 from $50.
08/02/17
08/02/17
UPGRADE

On The Fly: Top five analyst upgrades
Catch up on today's top five analyst upgrades with this list compiled by The Fly: 1. Pfizer (PFE) upgraded to Outperform from Market Perform at BMO Capital with analyst Alex Arfaei saying he expects "positive updates" on the company's pipeline that could improve investors' view on the company. 2. Royal Caribbean (RCL) upgraded to Neutral from Sell at Goldman Sachs with analyst Stephen Grambling citing "strong" leisure trends following the company's better than expected second quarter results. 3. Illumina (ILMN) upgraded to Equal-Weight from Underweight at First Analysis with analyst Joseph Munda saying concerns regarding sequencing overcapacity in the marketplace and the potential rate of adoption for NovaSeq are diminishing based on performance in the quarter. 4. Agios Pharmaceuticals (AGIO) upgraded to Outperform from Market Perform at Leerink with analyst Michael Schmidt citing his higher-level conviction regarding the commercial opportunity for its IDH inhibitors Idhifa and ivosidenib in acute myeloid leukemia following Idhifa FDA-approval and his recent checks indicating a high degree of enthusiasm for these agents in the physician community pointing to potential good initial uptake. 5. Sonoco Products (SON) upgraded to Hold from Sell at Vertical Research with analyst Chip Dillion citing valuation. This list is just a portion of The Fly's full analyst coverage. To see The Fly's full Street Research coverage, click here.
09/14/17
RBCM
09/14/17
INITIATION
Target $78
RBCM
Outperform
Agios Pharmaceuticals initiated with an Outperform at RBC Capital
RBC Capital analyst Kennen MacKay initiated Agios Pharmaceuticals with an Outperform and a $78 price target.
09/18/17
JPMS
09/18/17
NO CHANGE
Target $76
JPMS
Overweight
Agios Pharmaceuticals price target raised to $76 from $71 at JPMorgan
JPMorgan analyst Anupam Rama raised his price target for Agios Pharmaceuticals to $76 after conducting a survey of 26 U.S. hematologists. The survey indicated there is broader awareness of Idhifa, "encouraging views" on its efficacy and "rapid uptake," Rama tells investors in a research note. The analyst reiterates an Overweight rating on Agios.

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