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BOLD

Audentes Therapeutics

$35.53

1.62 (4.78%)

07:01
01/04/18
01/04
07:01
01/04/18
07:01

Audentes Therapeutics reports 'positive' data from first dose cohort of ASPIRO

Audentes Therapeutics announced positive interim data from the first dose cohort of ASPIRO, a Phase 1/2 clinical trial of AT132 in patients with X-Linked Myotubular Myopathy. ASPIRO is a multicenter, multinational, open-label, ascending dose study to evaluate the safety and preliminary efficacy of AT132 in approximately 12 XLMTM patients less than five years of age. "The early AT132 efficacy data observed in our first dose cohort of patients have exceeded our expectations," stated Dr. Suyash Prasad, Senior Vice President and Chief Medical Officer of Audentes. "At the 12-week timepoint, Patient 1 has improved from a severely compromised baseline to achieve a CHOP-INTEND score and maximal inspiratory pressure that are approaching the ranges normally seen in healthy children. Importantly, Patient 1 has also attained several age-appropriate developmental milestones within this time period, including head-control, rolling over and sitting unassisted. While still early in the trial, we view these initial efficacy data as a promising indicator of the potential for AT132 to bring meaningful benefit to patients and families living with this devastating disease."

BOLD Audentes Therapeutics
$35.53

1.62 (4.78%)

11/15/17
LEER
11/15/17
NO CHANGE
Target $29
LEER
Outperform
Audentes Therapeutics price target raised to $29 from $22 at Leerink
Leerink analyst Joseph Schwartz raised his price target for Audentes Therapeutics to $29 from $22 saying it has made significant progress with upcoming catalysts for AT132 and AT342. Larger programs are also advancing towards IND filing, both of which are expected to occur in 2018, he adds. The analyst reiterates an Outperform rating on the shares.
12/05/17
BMOC
12/05/17
INITIATION
Target $35
BMOC
Outperform
Audentes Therapeutics initiated with an Outperform at BMO Capital
BMO Capital analyst Matthew Luchini started Audentes Therapeutics with an Outperform rating and $35 price target. The company is an "emerging" gene therapy company focused on treating rare diseases with few or no treatment options, the analyst tells investors in a research note. He believes its pipeline provides opportunities for long-term upside.
12/12/17
PIPR
12/12/17
NO CHANGE
Target $36
PIPR
Overweight
Audentes Therapeutics stock to run further on AT132 data, says Piper Jaffray
Piper Jaffray analyst Christopher Raymond assumed coverage of Audentes Therapeutics with an Overweight rating and a price target of $36. Raymond says that despite the 56% year-to-date price gain, shares are "poised for another leg higher" on initial human data on lead program AT132 next month and second program AT342 for Crigler Najjar starting to dose patients in its Phase 1/2 VALENS study in Q1 of 2018.
12/20/17
HCWC
12/20/17
INITIATION
Target $37
HCWC
Buy
Audentes Therapeutics initiated with a Buy at H.C. Wainwright
H.C. Wainwright analyst Debjit Chattopadhyay started Audentes Therapeutics with a Buy rating and $37 price target. The analyst views the company's market positioning in AAV-based gene therapy as compelling and believes 2018 is "catalyst-filled."

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