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PTGX

Protagonist Therapeutics

$21.02

-0.13 (-0.61%)

08:08
01/04/18
01/04
08:08
01/04/18
08:08

Protagonist Therapeutics granted two U.S. patents for peptide drug candidates

Protagonist Therapeutics announced that two new U.S. patents have been issued for the company's novel peptide drug candidates, PTG-100 and PTG-300. The first patent covers methods of treating inflammatory bowel diseases with PTG-100, an orally stable alpha-4-beta-7 integrin peptide inhibitor. PTG-100 is currently in Phase 2b testing in patients with moderate-to-severe, active ulcerative colitis. The new patent adds to two previously granted U.S. patents which also provide protection for the company's alpha-4-beta-7 integrin peptide inhibitors, including PTG-100. The second patent covers peptide analogues of hepcidin, including PTG-300, and related pharmaceutical compositions. PTG-300, the company's lead peptide hepcidin mimetic, recently completed a Phase 1 clinical study in healthy volunteers. Protagonist plans to initiate Phase 2 trials of PTG-300 in patients with beta-thalassemia and myelodysplastic syndrome during 2018.

  • 26

    Feb

PTGX Protagonist Therapeutics
$21.02

-0.13 (-0.61%)

05/30/17
BMOC
05/30/17
NO CHANGE
Target $45
BMOC
Outperform
Protagonist Therapeutics price target raised to $45 on licensing at BMO Capital
BMO Capital analyst Ian Somaiya raised Protagonist Therapeutics' price target to $45 from $34 and reiterated his Overweight rating citing the PGG-200 licensing deal with Janssen. The analyst said the deal increases the probability of clinical and regulatory success in Crohn's and ulcerative colitis and likely reduces the need for future financings.
05/31/17
BMOC
05/31/17
NO CHANGE
BMOC
Protagonist Therapeutics price target raised to $45 from $34 at BMO Capital
BMO Capital analyst M. Ian Somaiya increased his price target on Protagonist (PTGX) after the company reached a licensing deal with Johnson & Johnson (JNJ) for its PTG-200 drug. The analyst says that the deal increases the drug's chances of success , and he calls J&J "an ideal partner." Somaiya keeps an Outperform rating on the stock.
06/01/17
LEER
06/01/17
NO CHANGE
Target $35
LEER
Outperform
Protagonist Therapeutics price target raised to $35 from $29 at Leerink
Leerink analyst Joseph Schwartz raised his price target for Protagonist Therapeutics to $35 citing the "attractive" partnership for PTG-200. The analyst reiterates an Outperform rating on the shares.
07/21/17
BTIG
07/21/17
INITIATION
BTIG
Buy
Protagonist Therapeutics initiated with a Buy at BTIG
BTIG analyst Timothy Chiang started coverage of Protagonist with a $36 price target and a Buy rating. The analyst says that the company's oral peptide technology platform "shows promise for treating inflammatory bowel disease." He says that the mechanisms of action of two of the company's drugs "have already been clinically validated by approved treatments for patients that have not adequately responded to TNF-blockers and other existing treatments ."

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