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TGTX

TG Therapeutics

$9.10

0.25 (2.82%)

07:40
01/08/18
01/08
07:40
01/08/18
07:40

TG Therapeutics announces global license agreement with Jiangsu Hengrui

TG Therapeutics and Jiangsu Hengrui Medicine announced that the companies have entered into an exclusive global license agreement pursuant to which TG Therapeutics will obtain worldwide rights, excluding Asia but including Japan, for the development of Hengrui's Bruton's Tyrosine Kinase inhibitor program, including lead candidate TG-1701, as monotherapy and in combination with ublituximab, TG's glycoengineered anti-CD20 monoclonal antibody, and umbralisib, TG's next generation PI3K-delta inhibitor. In addition to TG-1701, the global license agreement covers TG-1702, another BTK inhibitor in pre-clinical development. Under the terms of the agreement, Hengrui will receive an up-front licensing fee and near-term milestones, payable in TG common stock, and will be eligible to receive additional payments contingent on certain clinical, regulatory, and commercial milestones, totaling approximately $350M, as well as tiered royalties on net sales. Michael S. Weiss, Executive Chairman and CEO of TG Therapeutics stated, "We are pleased to be partnering with one of the leading Chinese biopharmaceutical companies. We have been evaluating potential BTK inhibitors for quite some time and we were really impressed with Hengrui's research that led to the development of these two highly selective BTK inhibitors. We believe TG-1701 could be comparable to the best-in-class BTK inhibitors and in combination with ublituximab and umbralisib, could represent a truly unique triple combination treatment option across CLL and NHL...With this license, we have taken a major step toward the development of a next generation, wholly-owned, proprietary, triplet therapy. Our goal is to advance TG-1701 into the clinic as quickly as possible in the first half of this year."

TGTX TG Therapeutics
$9.10

0.25 (2.82%)

10/03/17
RHCO
10/03/17
NO CHANGE
RHCO
TG Therapeutics has positive read through from Bayer approval, says SunTrust
SunTrust analyst Yatin Suneja believes that the FDA's decision to grant accelerated approval to Bayer's (BAYRY) Aliqopa, a PI3K-delta inhibitor, as a treatment for Relapsed/Refractory Follicular Lymphoma, bodes well for TG Therapeutics' (TGTX) own PI3K-delta inhibitor, TGR-120. The analyst says that the lack of a black box warning on Bayer's Aliqopa shows that not all PI3K-delta inhibitors have the safety issues that have been attributed to them in the past. Suneja says that "Aliqopa's approval reflects positively on TGR-1202, which offers best-in-class safety , and provides clarity on TGR-1202's regulatory pathway in" lymphoma The analyst says that investors are "overlooking" its potential in " lymphoma, and keeps a Buy rating on the shares.
10/17/17
JEFF
10/17/17
NO CHANGE
Target $23
JEFF
Buy
TG Therapeutics 16% selloff yesterday 'excessive,' says Jefferies
Jefferies analyst Matthew Andrews calls the 16% pullback yesterday in shares of TG Therapeutics "excessive" and recommends buying the dip. The FDA feedback that use of overall response rate to support accelerated approval is a review issue "seems obvious and not a major negative," Andrews tells investors in a research note. The agency working with TG to identify how to use the Genuine study's progression free survival to support full approval is positive, suggesting it sees ublituximab's benefit in chronic lymphocytic leukemia, the analyst adds. Andrews keeps a Buy rating on TG Therapeutics with a $23 price target.
10/18/17
RHCO
10/18/17
NO CHANGE
RHCO
Buy
TG Therapeutics selloff overdone, says SunTrust
SunTrust analyst Yatin Suneja said the selloff in Buy rated TG Therapeutics is a buying opportunity and would buy shares aggressively ahead of TG-1101's upcoming data presentation at ECTRMIS.
11/14/17
HCWC
11/14/17
INITIATION
Target $33
HCWC
Buy
TG Therapeutics assumed with a Buy at H.C. Wainwright
H.C. Wainwright analyst Edward White assumed coverage of TG Therapeutics with a Buy rating and $33 price target. The analyst views the recent share decline as a buying opportunity.

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