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TSRO

Tesaro

$69.59

-2.07 (-2.89%)

17:32
01/12/18
01/12
17:32
01/12/18
17:32

TESARO updates VARUBI injectible emulsion package insert

TESARO announced that it has updated the VARUBI injectable emulsion package insert in collaboration with the U.S. Food and Drug Administration. VARUBI injectable emulsion is a substance P/neurokinin receptor antagonist indicated for the prevention of delayed nausea and vomiting associated with chemotherapy in adults. The changes to the labeling include modifications to the CONTRAINDICATIONS, WARNINGS and PRECAUTIONS, and ADVERSE REACTIONS sections. Following its introduction in late November 2017, TESARO estimates that at least 7,000 doses of VARUBI injectable emulsion have been administered to patients receiving emetogenic chemotherapy in the United States. Anaphylaxis, anaphylactic shock and other serious hypersensitivity reactions have been reported in the postmarketing setting, some requiring hospitalization. These reactions have occurred during or soon after the infusion of VARUBI injectable emulsion. Most reactions have occurred within the first few minutes of administration.

TSRO Tesaro
$69.59

-2.07 (-2.89%)

12/20/17
SBSH
12/20/17
NO CHANGE
Target $135
SBSH
Buy
Tesaro price target lowered to $135 from $216 at Citi
Citi analyst Robyn Karnauskas lowered her price target for Tesaro to $135 but keeps a Buy rating on the shares. The analyst removed the takeover premium in her model and lowered her peak Varubi sales estimate to $400M from $685M. She notes, however, that her firm's PARP survey in ovarian cancer suggests majority market share for Tesaro's Zejula. In a worst case scenario, where the ovarian cancer market is split three ways, Tesaro shares would be valued at $63, the analyst tells investors in a research note.
12/29/17
PIPR
12/29/17
NO CHANGE
PIPR
Biotech fund outflows continue, says Piper Jaffray
For the weekly period ending Wednesday, December 27, healthcare/biotech funds saw $338M in net outflows, representing a 0.58% decrease in assets, Piper Jaffray analyst Christopher Raymond tells investors in a research note. This marks the seventh straight negative week and the eleventh week of outflows in the past 12 weeks, the analyst points out in a research note titled "Ending 2017 on a Down Note: Biotech Outflows Continue."
01/02/18
PIPR
01/02/18
NO CHANGE
Target $80
PIPR
Neutral
Tesaro price target lowered to $80 from $117 at Piper Jaffray
Piper Jaffray analyst Christopher Raymond lowered his price target for Tesaro to $80 while keeping a Neutral rating on the shares. Feedback from the company and an analysis of the FDA's adverse event database suggest Zejula estimates, both near- and longer-term, need to come down, Raymond tells investors in a research note. He believes initial assumptions around duration of therapy, dose and market share are too high. The analyst sees consensus numbers coming down, creating an unattractive setup for Tesaro shares.
01/02/18
COWN
01/02/18
NO CHANGE
Target $80
COWN
Market Perform
Tesaro price target lowered to $80 from $125 at Cowen
Cowen analyst Boris Peaker adjusted his Tesaro (TSRO) model to reflect the initial launch metrics for Zejula and the early limited uptake of PARP maintenance therapy in real-world practice. Since the drug became available, management has noted that so far only about 25% of the real-world NOVA population is receiving PARP maintenance, with the majority of these patients continuing to receive chemotherapy or nothing at all under a "watch and wait" protocol, noted Peaker. While Zejula is the best-in-class in PARP inhibitor at this time, Peaker also believes that at least Clovis' (CLVS) Rubraca may get a similar label over the next 6-12 months, he added. Peaker lowered his price target on Tesaro shares to $80 from $125 and keeps a Market Perform rating on the stock.

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ROST

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SNAP

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MRK

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MCD

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YRD

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