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TCON

TRACON Pharmaceuticals

$3.05

0.05 (1.67%)

10:02
01/19/18
01/19
10:02
01/19/18
10:02

TRACON reports partial responses by Recist 1.1 in 25% of patients in study

TRACON Pharmaceuticals announced that initial clinical data from its ongoing Phase 1b/2 study of TRC105 and Nexavar in patients with advanced hepatocellular carcinoma were presented in a poster presentation at the 2018 ASCO Gastrointestinal Cancers Symposium in San Francisco, California.Initial data from the ongoing open-label, non-randomized study were presented by Dr. Kanwal Raghav from the University of Texas MD Anderson Cancer Center: Partial responses by RECIST 1.1 occurred in 2 of 8 evaluable patients and a reduction of 50% or greater in alpha fetoprotein concentration occurred in 3 of 8 evaluable patients. Reduction in AFP, a tumor marker expressed in patients with HCC, in early treatment may help identify a favorable response to treatment and was observed in both cases of partial response. Hybrid dosing consisting of four weekly doses of TRC105 at 10 mg/kg followed by every other week dosing at 15 mg/kg thereafter was tolerable when given with the standard Nexavar dose of 400 mg twice daily. Adverse events typical of each drug did not increase in frequency or severity when the drugs were administered concurrently. The trial is ongoing, with the completion of the enrollment of approximately 33 patients expected by the end of 2018.

TCON TRACON Pharmaceuticals
$3.05

0.05 (1.67%)

06/13/17
STFL
06/13/17
NO CHANGE
STFL
TRACON price target lowered to $6 from $14 at Stifel
Stifel analyst Thomas Shrader lowered his price target on TRACON (TCON) after Acceleron (ALRN) announced results from its Phase II study of dalantercept. The analyst says that TRACON's drug targets the same pathway as Acceleron's treatment, although "there are important differences" between the drugs and Sharder still thinks that TRACON's drug can provide "tumor killing" benefits. However, the analyst reduced TRC105's probability of success in RCC and HCC to 50%. But the analyst keeps a Buy rating on the stock.

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EGN

Energen

$56.82

2.52 (4.64%)

16:52
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Energen management to meet with Morgan Stanley »

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AYX

Alteryx

$33.38

-0.37 (-1.10%)

16:32
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Alteryx acquires master distributor, Alteryx ANZ in Sydney »

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ICL

ICL

$4.43

0.08 (1.84%)

, NSTC

Ness Technologies

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ICL names Raviv Zoller as new CEO »

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ICL

$4.43

0.08 (1.84%)

NSTC

Ness Technologies

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LJPC

La Jolla

$32.15

-0.46 (-1.41%)

16:27
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NEXA

Nexa Resources

$19.43

-0.52 (-2.61%)

16:14
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Nexa Resources management to meet with Morgan Stanley »

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JPMorgan healthcare analyst to hold an analyst/industry conference call »

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MDT

Medtronic

$80.39

-0.02 (-0.02%)

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BRK.A

Berkshire Hathaway

$304,020.01

2616.01 (0.87%)

, BRK.B

Berkshire Hathaway

$202.76

2.03 (1.01%)

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Buffett believes Berkshire can handle $400B mega-catastrophe »

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Berkshire Hathaway

$304,020.01

2616.01 (0.87%)

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Berkshire Hathaway

$202.76

2.03 (1.01%)

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BRK.A

Berkshire Hathaway

$304,020.01

2616.01 (0.87%)

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Berkshire Hathaway

$202.76

2.03 (1.01%)

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Periodicals
Buffet says laments inability to find targets for Berkshire to buy, Reuters says »

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BRK.A

Berkshire Hathaway

$304,020.01

2616.01 (0.87%)

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Berkshire Hathaway

$202.76

2.03 (1.01%)

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BRK.A

Berkshire Hathaway

$304,020.01

2616.01 (0.87%)

, BRK.B

Berkshire Hathaway

$202.76

2.03 (1.01%)

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Berkshire Hathaway reports record profit fueled by tax reform, Reuters says »

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Berkshire Hathaway

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TWTR

Twitter

$32.66

0.55 (1.71%)

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Twitter's SoundCloud investment officially wiped out, Recode reports »

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AAPL

Apple

$175.50

3 (1.74%)

16:08
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Apple to store sensitive encryption keys in China, WSJ reports »

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VLKAY

Volkswagen

$40.98

0.09 (0.22%)

16:00
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Volkswagen's U.S. unit settles emissions suit, Reuters reports »

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DAL

Delta Air Lines

$53.46

0.91 (1.73%)

, UAL

United Continental

$67.57

0.87 (1.30%)

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Delta, United Airlines cut ties with NRA, Reuters reports »

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DAL

Delta Air Lines

$53.46

0.91 (1.73%)

UAL

United Continental

$67.57

0.87 (1.30%)

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BRK.A

Berkshire Hathaway

$304,020.01

2616.01 (0.87%)

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Berkshire Hathaway

$202.76

2.03 (1.01%)

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Berkshire Hathaway reports Q4 operating EPS $3,338, consensus $2,622.23 »

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BRK.A

Berkshire Hathaway

$304,020.01

2616.01 (0.87%)

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Berkshire Hathaway

$202.76

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TWX

Time Warner

$94.70

0.33 (0.35%)

, T

AT&T

$36.72

0.25 (0.69%)

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TWX

Time Warner

$94.70

0.33 (0.35%)

T

AT&T

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JKHY

Jack Henry

$121.95

1.79 (1.49%)

12:59
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Jack Henry management to meet with Stephens »

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PFBC

Preferred Bank

$64.05

0.86 (1.36%)

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Preferred Bank management to meet with Stephens »

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R

Ryder

$74.54

0.19 (0.26%)

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Ryder management to meet with Stephens »

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ASPU

Aspen Group

$8.85

1.48 (20.08%)

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TWTR

Twitter

$32.66

0.55 (1.71%)

, AOBC

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$10.00

-0.12 (-1.19%)

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TWTR

Twitter

$32.66

0.55 (1.71%)

AOBC

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$10.00

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RGR

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$49.90

0.9 (1.84%)

X

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$43.52

0.54 (1.26%)

STLD

Steel Dynamics

$47.47

-0.53 (-1.10%)

NUE

Nucor

$66.94

-0.01 (-0.01%)

AKS

AK Steel

$5.50

-0.12 (-2.14%)

AET

Aetna

$175.55

0.49 (0.28%)

ANTM

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$235.24

1.56 (0.67%)

CNC

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CI

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$194.79

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HNT

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HUM

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MOH

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UNH

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$230.16

3.07 (1.35%)

WCG

WellCare

$192.05

0.03 (0.02%)

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DBX

Dropbox

, SNAP

Snap

$17.45

-0.06 (-0.34%)

09:49
02/24/18
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Dropbox IPO bodes well, Barron's says »

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DBX

Dropbox

SNAP

Snap

$17.45

-0.06 (-0.34%)

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IPG

Interpublic Group

$24.24

0.3 (1.25%)

, OMC

Omnicom

$77.31

0.52 (0.68%)

09:42
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Advertising companies cheaper than usual, Barron's says »

After a tumble last year,…

IPG

Interpublic Group

$24.24

0.3 (1.25%)

OMC

Omnicom

$77.31

0.52 (0.68%)

PUBGY

Publicis

$18.82

0.09 (0.48%)

WPP

WPP

$95.30

0.93 (0.99%)

03/08/13
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MSFT

Microsoft

$94.06

2.33 (2.54%)

, INTC

Intel

$47.73

1.93 (4.21%)

09:36
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Quantum computing soon to be reality, Barron's says »

Microsoft (MSFT) predicts…

MSFT

Microsoft

$94.06

2.33 (2.54%)

INTC

Intel

$47.73

1.93 (4.21%)

NVDA

Nvidia

$245.93

3.78 (1.56%)

MU

Micron

$46.53

2.28 (5.15%)

GOOG

Alphabet

$1,126.79

20.16 (1.82%)

GOOGL

Alphabet Class A

$1,128.09

18.19 (1.64%)

AMZN

Amazon.com

$1,500.00

14.66 (0.99%)

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AMZN

Amazon.com

$1,500.00

14.66 (0.99%)

09:26
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Many downsides when Amazon's HQ2 comes to town, Barron's says »

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