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ATNX

Athenex

$17.33

0.12 (0.70%)

07:04
01/22/18
01/22
07:04
01/22/18
07:04

Athenex announces results of first cohort of Phase 1b clinical trial of Oraxol

Athenex announced the completion of the first cohort of patients in its Phase 1b clinical trial of Oraxol plus CYRAMZA in gastric cancer patients that failed previous chemotherapies. Oraxol, an innovative development in the treatment of cancer, is a novel oral formulation of paclitaxel, a very effective and commonly used chemotherapy treatment for many cancers, combined with HM30181A. A previously completed Phase II clinical trial of Oraxol in the second-line treatment of gastric cancer patients showed an encouraging overall median survival of 10.7 months. The expected overall survival for advanced gastric cancer patients who have failed previous chemotherapy and do not receive second-line therapy is approximately 4.0 months. Of the six patients in the first cohort, the Oraxol and ramucirumab combination treatment was well tolerated. Grade 4 neutropenia occurred in one patient who fully recovered and there were no patient deaths. There was no neuropathy. Two patients had partial responses and three patients had stable diseases. Only one patient had progressive disease. Although early, these results are regarded as encouraging compared with previous IV paclitaxel and ramucirumab combination therapy Phase III clinical trial results. Athenex is advancing to the second cohort with Oraxol dose escalation.

ATNX Athenex
$17.33

0.12 (0.70%)

09/14/17
RBCM
09/14/17
INITIATION
Target $35
RBCM
Outperform
Athenex initiated with an Outperform at RBC Capital
RBC Capital analyst Kennen MacKay initiated Athenex with an Outperform and a $35 price target telling investors its oral paclitaxel has the potential to achieve blockbuster sales in breast and gastric cancer. He sees Oraxol ph3 de-risking Athenex's other oral chemotherapies in development and the API business adding non-dilutive cash flow to fund pipeline programs as ATNX establishes a foothold in the branded business.
09/18/17
FBCO
09/18/17
INITIATION
Target $25
FBCO
Outperform
Athenex initiated with an Outperform at Credit Suisse
Credit Suisse analyst Iris Wang started Athenex with an Outperform rating and $25 price target. The company's pipeline of orally delivered chemotherapeutic agents offers an attractive risk-reward profile, Wang tells investors in a research note titled "An emerging biotech unicorn."
09/18/17
09/18/17
INITIATION

On The Fly: Top five analyst initiations
Catch up on today's top five analyst initiations with this list compiled by The Fly: 1. Teck Resources (TECK) initiated with a Sell at Axiom. 2. GenMark (GNMK) initiated with a Buy at BofA/Merrill. 3. Cirrus Logic (CRUS) initiated with an Underperform at BofA/Merrill. 4. Athenex (ATNX) initiated with an Outperform at Credit Suisse. 5. Brookfield Infrastructure (BIP) reinitiated with a Neutral at Credit Suisse. This list is just a portion of The Fly's analyst coverage. To see The Fly's full Street Research coverage, click here.
01/17/18
DBAB
01/17/18
NO CHANGE
Target $20
DBAB
Buy
Athenex feedback from FDA removes key overhang, says Deutsche Bank
The positive FDA feedback, where Athenex and the agency agreed on an ongoing Phase 3 study as a registration study, effectively removed a key regulatory overhang of the stock, Deutsche Bank analyst Jack Hu tells investors in a research note. The analyst had been concerned that FDA might not approve Oraxol even if the trial turns out to be successful. He now believes, however, that the Phase 3 study has "much reduced" regulatory risks. The analyst keeps a Buy rating on Athenex with a $20 price target.

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