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ARQL

ArQule

$1.57

-0.05 (-3.09%)

07:10
02/07/18
02/07
07:10
02/07/18
07:10

ArQule, Roivant Sciences enter into license agreement for derazantinib in China

Roivant Sciences and ArQule announced the initiation of a collaboration to pursue the development of derazantinib, a pan-FGFR inhibitor, in Greater China. As part of the collaboration, ArQule has granted a Roivant subsidiary an exclusive license to develop and commercialize derazantinib in the People's Republic of China, Hong Kong, Macau, and Taiwan. Deal terms include an upfront payment to ArQule of $3 million and an additional $2.5M development milestone within the first year. ArQule is also eligible for regulatory and commercial milestones and royalties on future sales of derazantinib in Greater China. ArQule is currently conducting a registrational trial for derazantinib in the United States and Europe as a potential treatment for intrahepatic cholangiocarcinoma , a form of biliary tract cancer. The People's Republic of China has one of the world's highest incidences of iCCA, where it is the second most common form of liver cancer. Roivant intends to pursue the development of derazantinib in China for the treatment of iCCA while also pursuing further development in other tumor types with high rates of FGFR mutation.

ARQL ArQule
$1.57

-0.05 (-3.09%)

02/02/18
RILY
02/02/18
INITIATION
Target $3
RILY
Buy
ArQule initiated with a Buy at B. Riley FBR
B. Riley FBR analyst George Zavoico earlier today initiated ArQule with a Buy rating and $3 price target. The analyst notes there are no approved drugs for second-line treatment of advanced or metastatic intrahepatic cholangiocarcinoma, which the company's derazantinib is testing in a Phase III clinical trial.
12/14/17
NEED
12/14/17
UPGRADE
Target $5
NEED
Buy
ArQule upgraded to Buy at Needham ahead of 'transformative' 2018
As reported earlier, Needham analyst Chad Messer upgraded ArQule to Buy from Hold with a $5 price target. Messer says the recent developments - miransertib trials for Proteus syndrome, Phase Ia/b data for the BTK-inhibitor ARQ531, and interim pivotal data for derazantn - make this the appropriate time to "step up and buy shares" ahead of a "potentially transformative 2018".
12/14/17
NEED
12/14/17
UPGRADE
NEED
Buy
ArQule upgraded to Buy from Hold at Needham

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