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BOLD

Audentes Therapeutics

$34.10

1.47 (4.51%)

11:06
02/07/18
02/07
11:06
02/07/18
11:06

Audentes Therapeutics selects clinical development candidate for Pompe program

Audentes Therapeutics last night announced it has selected an optimized clinical development candidate for its Pompe disease program. Data supporting the selection were presented today during a general session at the 14th Annual WORLDSymposium 2018. "We are very excited to present the data highlighting the immunological and glycogen reduction benefits provided by our novel hybrid promoter vector in the Pompe disease mouse model. This innovative design reflects our commitment to gene therapy vector engineering and immunology, and strengthens our hope for the translation of AT982 into a transformative therapy for the Pompe patient community," stated John Gray, PhD, Senior VP and Chief Scientific Officer. Audentes plans to file an IND for AT982 in the second quarter of 2018 and plans to initiate a Phase 1/2 clinical study in the fourth quarter of 2018.

BOLD Audentes Therapeutics
$34.10

1.47 (4.51%)

12/20/17
HCWC
12/20/17
INITIATION
Target $37
HCWC
Buy
Audentes Therapeutics initiated with a Buy at H.C. Wainwright
H.C. Wainwright analyst Debjit Chattopadhyay started Audentes Therapeutics with a Buy rating and $37 price target. The analyst views the company's market positioning in AAV-based gene therapy as compelling and believes 2018 is "catalyst-filled."
01/04/18
PIPR
01/04/18
NO CHANGE
Target $45
PIPR
Overweight
Piper ups Audentes target to $45 on 'far' better than expected data
Piper Jaffray analyst Christopher Raymond raised his price target for Audentes Therapeutics to $45 from $36 saying the initial data for AT132 in X-Linked Myotubular Myopathy is "far" better than expected." The stock in morning trading is up 13% to $40.08. While elevated troponin levels seen in one patient is noteworthy, mitigating circumstances, combined with "truly remarkable efficacy," more than offsets this concern, Raymond tells investors in a research note. The analyst believes six month data next quarter is likely to solidify AT132's therapeutic premise. He remains a buyer of Audentes shares with an Overweight rating.
01/04/18
WEDB
01/04/18
NO CHANGE
Target $56
WEDB
Outperform
Audentes price target raised to $56 from $29 at Wedbush
Wedbush analyst David Nierengarten raised his price target for Audentes Therapeutics to $56 saying the first dose cohort data from the Phase 1/2 trial for AT132 in X-Linked Myotubular Myopathy is "impressive." Treated patients experienced "significant and rapid improvements in several important functional metrics," Nierengarten tells investors in a research note. The analyst expects additional confirmatory updates throughout the year and keeps an Outperform on Audentes shares.
01/05/18
BMOC
01/05/18
NO CHANGE
Target $44
BMOC
Outperform
Audentes Therapeutics price target raised to $44 from $35 at BMO Capital
BMO Capital analyst Matthew Luchini raised his price target on Audentes Therapeutics to $44 after the company's release of initial AT132 Phase I/II data for the treatment of X-Linked Myotubular Myopathy. The analyst says the results offer a "proof of concept", adding he is encouraged by the improvements in neuromuscular and respiratory function from the treatment. Luchini keeps his Outperform rating on Audentes Therapeutics.

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