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CATB

Catabasis Pharmaceuticals

$1.25

0.02 (1.63%)

08:02
02/13/18
02/13
08:02
02/13/18
08:02

Catabasis: Edasalonexent substantially slowed DMD progression in study

Catabasis Pharmaceuticals reported new efficacy and safety results showing preservation of muscle function and sustained disease-modifying effects in boys with Duchene muscular dystrophy in the MoveDMD trial open-label extension following 48 and 60 weeks of treatment with edasalonexent. Consistent improvements in all assessments of muscle function were observed after more than a year of oral 100 mg/kg/day edasalonexent treatment compared to the rates of change in the pre-specified control period for boys prior to receiving edasalonexent treatment. Additionally, supportive changes in non-effort based measures of muscle health were seen, with significant longer-term reductions in muscle enzymes and C-reactive protein, supporting the durability of edasalonexent treatment effects. Edasalonexent continued to be well tolerated with no safety signals observed in the trial. These data will be presented on Saturday, February 17, 2018, at 14:15 CET at the XVI International Conference on Duchenne and Becker Muscular Dystrophy in Rome, Italy, and detailed at future scientific conferences. Catabasis plans to initiate a single global Phase 3 trial with edasalonexent in patients with DMD regardless of mutation type in the first half of 2018 with top-line results expected in 2020. Edasalonexent is a potential oral foundational therapy that is being developed for all patients affected by DMD.

CATB Catabasis Pharmaceuticals
$1.25

0.02 (1.63%)

08/14/17
OPCO
08/14/17
NO CHANGE
Target $4
OPCO
Outperform
Catabasis Pharmaceuticals price target lowered to $4 from $9 at Oppenheimer
Oppenheimer analyst Hartaj Singh lowered his price target for Catabasis Pharmaceuticals to $4 from $9 as a comprehensive Phase 3 program potentially pushes out sales timelines and reduces sales potential. The analyst reiterates an Outperform rating on the shares.
09/29/17
SBSH
09/29/17
NO CHANGE
Target $1.5
SBSH
Neutral
PTC panel vote not favorable for Catabasis despite share rally, says Citi
Catabasis Pharmaceuticals (CATB) shares traded 22% higher yesterday as an FDA panel considered the approval of PTC Therapeutics' (PTCT) Duchenne muscular dystrophy agent Translarna, Citi analyst Joel Beatty tells investors in a research note. The general tone of FDA comments support the view that the agency is willing to be flexible with regards to accepting a variety of outcomes as approvable endpoints in DMD, as long as they are prospectively defined, Beatty contends. The analyst, however, thinks Catabasis' edasalonexent and Translarna would likely be used synergistically and would not be competitors. As such, he does not see the negative vote at yesterday's panel meeting as being favorable for Catabasis. Beatty keeps a Neutral rating on Catabasis shares with a $1.50 price target. The stock closed yesterday up 22%, or 40c, to $2.23.
10/05/17
OPCO
10/05/17
NO CHANGE
Target $7
OPCO
Outperform
Catabasis Pharmaceuticals price target raised to $7 from $4 at Oppenheimer
Oppenheimer analyst Hartaj Singh raised his price target for Catabasis Pharmaceuticals to $7 from $4 after the company reported positive 36-week data from the ongoing Part C open label extension of its Phase 2 MoveDMD clinical trial in Duchenne muscular dystrophy. The analyst reiterates an Outperform rating on the shares.
11/20/17
SBSH
11/20/17
UPGRADE
Target $2.5
SBSH
Buy
Catabasis Pharmaceuticals upgraded to Buy from Neutral at Citi
Citi analyst Joel Beatty upgraded Catabasis Pharmaceuticals to Buy while lowering his price target for the shares to $2.50 from $3.50. Non-dilutive funding is possible for the Phase 3 trial given its low cost, which could provide upside to the current share price, Beatty tells investors in a research note. He believes the extension study data in Q1 of 2018 could help attract some non-dilutive financing.

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TELNY

Telenor

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$71.05

-1.77 (-2.43%)

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TNDM

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