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SYBX

Synlogic

$9.41

-0.13 (-1.36%)

08:10
02/13/18
02/13
08:10
02/13/18
08:10

Synlogic says preclinical data support advancement of IO program candidates

Synlogic announced the presentation of preclinical data from its Synthetic Biotic immuno-oncology program at the Keystone Symposium Lymphocytes and their Roles in Cancer. "These data provide compelling, early scientific evidence supporting the development of our Synthetic Biotic medicines as potential novel immunotherapeutic agents for the treatment of various cancers. The results demonstrate that we can design Synthetic Biotic medicines that dramatically modulate the tumor microenvironment, by generating potent and efficacious antitumor immunity, turning what is known as a "cold" tumor "hot" and resulting in greatly enhanced response rates. Our Synthetic Biotic medicines can be administered by intratumoral injection enabling achievement of these beneficial effects locally and without systemic toxicity. Moreover, we can engineer additional activities into this new class of living medicines that enhance and sustain the anti-tumor response. In the coming year we intend to advance these IO program candidates into IND-enabling studies," said J.C. Gutierrez-Ramos, Ph.D., Synlogic's president and CEO.

  • 04

    Apr

SYBX Synlogic
$9.41

-0.13 (-1.36%)

09/19/17
LEER
09/19/17
INITIATION
Target $25
LEER
Outperform
Synlogic initiated with an Outperform at Leerink
Leerink analyst Joseph Schwartz initiated Synlogic with an Outperform and a $25 price target. The analyst said Synlogic's 'synthetic biotics' aim to treat diseases which impact different organs by offering alternative metabolic pathways, usually located in the gut. Synlogic's agents may provide a parallel process for scavenging biological compounds which become toxic to patients when they are in excess due to faults in the preprogrammed natural manner, Schwartz wrote in a note to investors.
11/28/17
WEDB
11/28/17
INITIATION
Target $20
WEDB
Outperform
Synlogic initiated with an Outperform at Wedbush
Wedbush analyst David Nierengarten started Synlogic with an Outperform rating and $20 price target. The analyst believes the company's platform, which uses engineered bacteria to generate desired metabolites, has the potential to disrupt the current standard of care for a number of disorders.
01/29/18
PIPR
01/29/18
INITIATION
Target $16
PIPR
Overweight
Synlogic initiated with an Overweight at Piper Jaffray
Piper Jaffray analyst Edward Tenthoff started Synlogic with an Overweight rating and $16 price target. The company is pioneering development of synthetic biotics, the analyst contends.
01/29/18
01/29/18
INITIATION

On The Fly: Top five analyst initiations
Catch up on today's top five analyst initiations with this list compiled by The Fly: 1. PepsiCo (PEP) initiated with a Hold at SunTrust. 2. Synlogic (SYBX) initiated with an Overweight at Piper Jaffray. 3. Centennial Resource Development (CDEV) initiated with a Buy at Guggenheim. 4. Zynerba (ZYNE) initiated with a Buy at Ladenburg. 5. Radius Health (RDUS) initiated with an Overweight at Morgan Stanley. This list is just a portion of The Fly's analyst coverage. To see The Fly's full Street Research coverage, click here.

TODAY'S FREE FLY STORIES

AUTL

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FNSR

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AUTL

Autolus Therapeutics

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  • 22

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NUVA

NuVasive

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0.33 (0.59%)

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HAIN

Hain Celestial

$30.23

1.04 (3.56%)

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APO

Apollo Global

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0.15 (0.61%)

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APO

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CMG

Chipotle

$472.84

9.97 (2.15%)

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PAGS

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$30.52

1.1 (3.74%)

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GM

General Motors

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, F

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F

Ford

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HMC

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TM

Toyota

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VLKAY

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DDAIF

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FCAU

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  • 10

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QGEN

Qiagen

$36.61

0.41 (1.13%)

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  • 22

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CMC

Commercial Metals

$23.22

0.96 (4.31%)

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STG

Sunlands Online

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, MU

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On The Fly: Top five analyst initiations »

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STG

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MU

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IDXG

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AYX

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BCRX

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NKE

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NKE

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URI

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URI

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Southern Company

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IO

ION Geophysical

$21.85

0.5 (2.34%)

, SLB

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IO

ION Geophysical

$21.85

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SLB

Schlumberger

$67.20

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  • 26

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WMT

Walmart

$84.47

0.25 (0.30%)

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PX

Praxair

$157.72

2 (1.28%)

10:20
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Praxair calls active as shares see strength »

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10:20
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More from Markit: the "strong" end to Q2 data "round off the best quarter for three years »

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IO

ION Geophysical

$21.85

0.5 (2.34%)

10:19
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Breaking Hot Stocks news story on ION Geophysical »

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  • 26

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