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CLLS

Cellectis

$30.09

1.22 (4.23%)

08:11
02/13/18
02/13
08:11
02/13/18
08:11

Cellectis announces issuance of two U.S. patents for CRISPR use in T-cells

Cellectis announced the issuance of two U.S. patents - US 9,855,297 and US 9,890,393 - for the invention of certain uses of RNA-guided endonucleases, such as Cas9 or Cpf1, for the genetic engineering of T-cells. Both patents claim methods by which T-cells are gene edited using transient expression of CRISPR/Cas9 components. The patents came into force on January 2, 2018 and February 13, 2018, respectively.

  • 04

    Apr

CLLS Cellectis
$30.09

1.22 (4.23%)

09/05/17
RHCO
09/05/17
DOWNGRADE
RHCO
Hold
Cellectis downgraded to Hold from Buy at SunTrust
09/05/17
FBCO
09/05/17
NO CHANGE
FBCO
Outperform
No read through to Gilead, Kite from Cellectis clinical hold, says Credit Suisse
Credit Suisse analyst Alethia Young said the safety issues that Cellectis (CLLS) is encountering, and which prompted a clinical hold be placed on the company's allogenic CAR-T drug, UCART123, could be to some degree related to the company's platform. She adds that CRS, which led to a death in Cellectis' BPDCN study, is a known issue with CAR-T technologies and cases have been seen in Juno (JUNO) and Kite's (KITE) programs as well. The analyst, who doesn't think there is a read through to Kite and Gilead (GILD) from the Cellectis news and remains confident Kite will receive approval later this fall and launch Axi-Cel, keeps an Outpeform rating on Gilead shares.
09/06/17
RHCO
09/06/17
DOWNGRADE
RHCO
Hold
Cellectis downgraded on patient death, study halt at SunTrust
As noted earlier, SunTrust downgraded Cellectis to Hold from Buy. Analyst Peter Lawson downgraded the stock after a patient died during the company's BPDCN study, leading the FDA to place a clinical hold on both Phase 1 studies of Cellectis' UCART123, a CAR-T drug. Target to $20 from $35.
12/28/17
OPCO
12/28/17
NO CHANGE
Target $40
OPCO
Outperform
Oppenheimer remains bullish on Cellectis
Oppenheimer analyst Hartaj Singh highlights Cellectis as a high-conviction idea. The analyst argues that the technical and development hurdles that the company must singularly solve for each product also creates a high barrier to entry. As the 60/40 divide between autologous/allogeneic bone marrow transplant - the closest analog to CAR-T currently - demonstrates, the scarcity value of Cellectis' approach may not be reflected in its current share price. Singh stays bullish, and reiterates an Outperform rating and $40 price target on the shares.

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NOG

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SNH

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NOG

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