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AKCA

Akcea Therapeutics

$22.58

0.41 (1.85%)

05:30
02/27/18
02/27
05:30
02/27/18
05:30

Akcea Therapeutics downgraded to Market Perform from Outperform at Wells Fargo

Wells Fargo analyst Jim Birchenough downgraded Akcea Therapeutics to Market Perform and lowered his price target for the shares to $20 from $27. With a new proposal to reduce volanesorsen dose to biweekly in lighter patients to mitigate risk of severe platelet reduction, the analyst sees increased regulatory risk on questions of adequacy of the lower dose in reducing triglycerides to key threshold levels and in reducing risk of pancreatitis. The analyst recommends taking a wait-and-see approach in the near term.

  • 26

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  • 10

    May

AKCA Akcea Therapeutics
$22.58

0.41 (1.85%)

08/08/17
WELS
08/08/17
INITIATION
Target $27
WELS
Outperform
Akcea Therapeutics initiated with an Outperform at Wells Fargo
Wells Fargo analyst Jim Birchenough started Akcea Therapeutics with an Outperform rating and $27 price target. The analyst sees potential blockbuster opportunity for the company's lead antisense oligonucleotide therapeutic volanesorsen in patients with familial chylomicronemia syndrome and other severe lipid disorders.
08/08/17
BMOC
08/08/17
INITIATION
BMOC
Outperform
Akcea Therapeutics initiated with an Outperform at BMO Capital
BMO Capital analyst Do Kim started coverage of Akcea with a $25 price target and an Outperform rating. The analyst says the company provides "a commercial-ready, rare disease drug opportunity, with a validating partnership lead candidate" at a "small-cap valuation." Kim predicts that the company's volanesorsen, a triglyceride-lowering drug being developed for two rare, severe genetic disorders, Familial Chylomicronemia Syndrome and Familial Partial Lipodystrophy, will be approved as a treatment for FCS in 2H18 and generate worldwide peak sales of $800M.
08/08/17
08/08/17
INITIATION

On The Fly: Top five analyst initiations
Catch up on today's top five analyst initiations with this list compiled by The Fly: 1. Amazon.com (AMZN), Alphabet (GOOG, GOOGL), and Facebook (FB) were reinstated with a Buy at Mizuho, while eBay (EBAY) and Twitter (TWTR) were reinstated with an Underperform. 2. Broadridge (BR) initiated with a Neutral at DA Davidson. 3. Brighthouse Financial (BHF) initiated with an Overweight at Barclays. 4. Akcea Therapeutics (AKCA) WAS initiated with an Outperform at BMO Capital and Cowen, an Outperform at Wells Fargo, as well as a Buy at Stifel. 5. Lockheed Martin (LMT) and Raytheon (RTN) were initiated with an Overweight at Morgan Stanley, while Northrop Grumman (NOC) was initiated with an Equal Weight, and General Dynamics (GD) was initiated with an Underweight at the firm. This list is just a portion of The Fly's analyst coverage. To see The Fly's full Street Research coverage, click here.
02/27/18
WELS
02/27/18
DOWNGRADE
WELS
Market Perform
Akcea Therapeutics downgraded to Market Perform from Outperform at Wells Fargo

TODAY'S FREE FLY STORIES

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HUBG

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JBHT

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SYRS

Syros Pharmaceuticals

$12.35

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EQGP

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EQT GP

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EQM

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RMP

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CRSP

Crispr Therapeutics

$59.61

-6.13 (-9.32%)

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MAS

Masco

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CRSP

Crispr Therapeutics

$59.09

-6.65 (-10.12%)

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ECA

Encana

$12.84

-0.4 (-3.02%)

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Options
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ADS

Alliance Data

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-23.32 (-9.58%)

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CRM

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YELP

Yelp

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LBIX

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STM

STMicroelectronics

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EDIT

Editas Medicine

$36.20

-1.71 (-4.51%)

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Intellia Therapeutics

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-2.05 (-6.29%)

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EDIT

Editas Medicine

$36.20

-1.71 (-4.51%)

NTLA

Intellia Therapeutics

$30.55

-2.05 (-6.29%)

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CVS

CVS Health

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-0.33 (-0.48%)

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$NSD

NASDAQ Market Internals

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13:17
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$NYE

NYSE Market Internals

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PEGI

Pattern Energy

$17.84

0.75 (4.39%)

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