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SLS

Sellas Life Sciences

$5.17

-0.11 (-2.08%)

08:53
02/27/18
02/27
08:53
02/27/18
08:53

Sellas Life Sciences announces data from Phase 2 trial of galinpepimut-S

SELLAS Life Sciences Group announced that data from the Phase 2 trial of its lead candidate, galinpepimut-S, in acute myeloid leukemia have been published in the current issue of Blood Advances. GPS met its pre-specified primary endpoint of greater than or equal to34% actual overall survival rate at three years with a GPS-induced OS rate of 47.4%. Median disease-free survival from first complete response was 16.9 months, while the overall survival from diagnosis has not yet been reached, but is predicted to be greater than 67.6 months. GPS targets the antigen, Wilms tumor 1 protein, which has been ranked by the National Cancer Institute as the leading target for cancer immunotherapy. For patients in the older cohort, median OS post-diagnosis was 35.8 months. Historical controls for comparable patients over sixty years of age who reach first complete remission show median OS since initial diagnosis of 9.5-15.8 months. The open-label Phase 2 study evaluated GPS in 22 adult patients with AML in CR1. Patients received 6 vaccinations administered over 10 weeks with the potential to receive 6 additional monthly doses if they remained in CR1. Immune responses were evaluated after the sixth and twelfth vaccinations by CD4+ T-cell proliferation, CD8+ T cell interferon-gamma secretion or the CD8-relevant WT1 peptide MHC tetramer assay. In the study, GPS was well tolerated, with the most common side effects being Grade 1/2 injection site reactions, fatigue, and skin induration. Fourteen patients completed more than six vaccinations, and nine received all 12 vaccine doses. Nine of 14 tested patients had an immune response in more than one of three assays used

  • 11

    Mar

TODAY'S FREE FLY STORIES

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Daimler AG

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, FCAU

Fiat Chrysler

$19.33

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Fiat Chrysler

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F

Ford

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GM

General Motors

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HMC

Honda

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NSANY

Nissan

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Toyota

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VLKAY

Volkswagen

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GOOG

Alphabet

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GOOGL

Alphabet Class A

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PFE

Pfizer

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NVS

Novartis

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1.47 (1.82%)

RHHBY

Roche

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SNY

Sanofi

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0.44 (1.05%)

BA

Boeing

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MRK

Merck

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ACN

Accenture

$166.47

-0.47 (-0.28%)

, EADSY

Airbus

$0.00

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ACN

Accenture

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EADSY

Airbus

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ATI

Allegheny Technologies

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0.08 (0.30%)

BAESY

BAE Systems

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CAE

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CW

Curtiss-Wright

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DASTY

Dassault Systemes

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ESLT

Elbit Systems

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0.64 (0.54%)

LMT

Lockheed Martin

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3.09 (0.97%)

BA

Boeing

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FNWB

First Northwest Bancorp

$16.11

0.36 (2.29%)

17:48
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First Northwest Bancorp names Terry Anderson chief credit officer »

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FCX

Freeport McMoRan

$15.75

-0.05 (-0.32%)

17:42
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Freeport McMoRan CAO Michael Arnold to retire »

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XLE

Energy Select Sector SPDR

$74.87

-0.24 (-0.32%)

, XLU

Utilities SPDR

$52.28

-0.39 (-0.74%)

17:39
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General news
Week ending ETF Scorecard: Financials lead, Energy slumps »

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XLE

Energy Select Sector SPDR

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XLU

Utilities SPDR

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IYR

DJ US Real Estate Index Fund

$80.23

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XLP

Consumer Staples Sector SPDR

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0.3 (0.57%)

XLY

Consumer Discretionary Sector SPDR

$112.15

-0.47 (-0.42%)

XLB

S&P Select Materials SPDR

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XLF

Financial Select Sector

$27.57

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XLV

Health Care Select Sector SPDR

$86.74

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XLK

Technology Select Sector SPDR

$72.55

0.01 (0.01%)

XLI

Industrial Select Sector SPDR

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GLD

SPDR Gold Trust

$116.56

0.74 (0.64%)

SLV

iShares Silver Trust

$14.59

0.18 (1.25%)

USO

United States Oil Fund

$14.15

0.025 (0.18%)

UNG

United States Natural Gas Fund

$22.38

-0.06 (-0.27%)

HYG

iShares iBoxx $ High Yield Corporate Bond

$85.62

0.03 (0.04%)

LQD

iShares iBoxx $ Investment Grade Corporate Bond

$115.27

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TLT

iShares 20+ Year Treasury Bond Fund

$120.78

-1.46 (-1.19%)

IEF

iShares 7-10 Year Treasury Bond ETF

$102.21

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SHY

iShares 1-3 Year Treasury Bond

$83.26

-0.005 (-0.01%)

IWD

iShares Russell 1000 Value

$123.07

-0.2897 (-0.23%)

IWF

iShares Russell 1000 Growth

$149.41

-0.04 (-0.03%)

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XRX

Xerox

$25.10

-0.095 (-0.38%)

, FUJIY

Fujifilm

$0.00

(0.00%)

17:25
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Xerox, Centerview settle matters related to proposed Fuji tie-up »

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XRX

Xerox

$25.10

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FUJIY

Fujifilm

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STON

StoneMor Partners

$3.61

-0.015 (-0.41%)

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TEF

Telefonica

$8.70

0.07 (0.81%)

17:11
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Telefonica rating change at Goldman Sachs »

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SPY

SPDR S&P 500 ETF Trust

$279.71

-0.24 (-0.09%)

, USO

United States Oil Fund

$14.15

0.025 (0.18%)

17:04
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SPY

SPDR S&P 500 ETF Trust

$279.71

-0.24 (-0.09%)

USO

United States Oil Fund

$14.15

0.025 (0.18%)

GLD

SPDR Gold Trust

$116.56

0.74 (0.64%)

FXE

Euro Currency Trust

$112.46

0.83 (0.74%)

FXC

CurrencyShares Canadian Dollar Trust

$75.17

0.81 (1.09%)

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CZWI

Citizens Community Bancorp

$14.15

(0.00%)

17:02
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Breaking Syndicate news story on Citizens Community Bancorp »

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PKD

Parker Drilling

$0.30

-0.0044 (-1.46%)

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Breaking Hot Stocks news story on Parker Drilling »

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  • 02

    Aug

RSLS

ReShape Lifesciences

$1.47

-0.02 (-1.34%)

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Breaking Hot Stocks news story on ReShape Lifesciences  »

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BOX

Box

$26.13

-0.26 (-0.99%)

16:57
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07/20
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Initiation
Box initiated at First Analysis »

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ALDX

Aldeyra

$7.95

-0.15 (-1.85%)

16:53
07/20/18
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Syndicate
Breaking Syndicate news story on Aldeyra »

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GLRE

Greenlight Capital Re

$14.00

-0.15 (-1.06%)

16:46
07/20/18
07/20
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Hot Stocks
Greenlight Capital Re announces departure of COO »

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RVI

Retail Value

$34.56

0.2 (0.58%)

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Breaking Hot Stocks news story on Retail Value »

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LECO

Lincoln Electric

$92.26

0.64 (0.70%)

, ROK

Rockwell Automation

$171.32

-0.71 (-0.41%)

16:35
07/20/18
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16:35
Hot Stocks
Lincoln Electric expands board to 11 directors, appoints Patrick Goris to board »

Lincoln Electric (LECO)…

LECO

Lincoln Electric

$92.26

0.64 (0.70%)

ROK

Rockwell Automation

$171.32

-0.71 (-0.41%)

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KMX

CarMax

$77.15

-0.57 (-0.73%)

16:33
07/20/18
07/20
16:33
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16:33
Hot Stocks
CarMax chairman sells 37,500 common shares »

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LOW

Lowe's

$100.65

-0.74 (-0.73%)

16:31
07/20/18
07/20
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Hot Stocks
Lowe's names Joseph McFarland as EVP of stores »

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16:30
07/20/18
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16:30
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16:30
Options
Preliminary option volume of 20.2M today »

Preliminary option volume…

PFE

Pfizer

$37.33

-0.03 (-0.08%)

16:26
07/20/18
07/20
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Hot Stocks
FDA approves Pfizer's Biosimilar NIVESTYM for all indications »

Pfizer announced that the…

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JCP

J.C. Penney

$2.50

-0.065 (-2.53%)

16:23
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J.C. Penney chief customer officer McFarland to leave company »

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VIX

Volatility Index S&P 500 Options

$0.00

(0.00%)

16:20
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Options
Closing CBOE SPX and VIX Index summary for July 20th »

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ASFI

Asta Funding

$3.15

-0.1 (-3.08%)

16:18
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Asta Funding receives Nasdaq non-compliance letter »

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$NSD

NASDAQ Market Internals

$0.00

(0.00%)

16:17
07/20/18
07/20
16:17
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16:17
Technical Analysis
NASDAQ market internals summary »

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