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IMMP

Immutep

$1.83

-0.01 (-0.54%)

, MRK

Merck

$55.14

0.38 (0.69%)

19:47
03/11/18
03/11
19:47
03/11/18
19:47

Immutep enters clinical trial collaboration, supply agreement with Merck

Immutep Limited announced that it has entered into a clinical trial collaboration and supply agreement with Merck (MRK) to evaluate the combination of Immutep's lead immunotherapy product candidate eftilagimod alpha with Merck's anti-PD-1 therapy Keytruda in a new clinical trial that will evaluate the combination in several different solid tumours. The planned Phase II clinical trial, referred to as TACTI-002, will evaluate the safety and efficacy of this novel immunotherapy combination in patients with non-small cell lung cancer, head and neck cancer, or ovarian cancer. The TACTI-002 clinical trial will be a Phase II, Simon two-stage, non-comparative, open-label, single-arm, multicentre clinical study. Up to 120 patients across the three indications are planned to be treated in medical centres in Europe and the United States with the trial expected to commence in the second half of 2018.

IMMP

Immutep

$1.83

-0.01 (-0.54%)

MRK

Merck

$55.14

0.38 (0.69%)

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IMMP Immutep
$1.83

-0.01 (-0.54%)

MRK Merck
$55.14

0.38 (0.69%)

02/14/18
BMOC
02/14/18
NO CHANGE
Target $65
BMOC
Outperform
Merck price target lowered to $65 from $70 at BMO Capital
BMO Capital analyst Alex Arfaei lowered his price target on Merck to $65 after the company discontinued its APECS study. The analyst sees this as "another setback that increases Merck's dependence on Keytruda" and contends that the company needs other meaningful drivers. Arfaei keeps his Outperform rating based on his confidence in Keytruda growth and Merck's Immuno-oncology execution.
02/15/18
PIPR
02/15/18
NO CHANGE
Target $407
PIPR
Overweight
Biogen selloff yesterday a buying opportunity, says Piper Jaffray
Piper Jaffray analyst Christopher Raymond recommends using the selloff yesterday in shares of Biogen (BIIB) as a buying opportunity. The stock pulled back after management disclosed at a conference plans to up-size the Phase 3 aducanumab program by 510 patients total. While "this is a bit unnerving," particularly on the heels of another Phase 3 Alzheimer's failure for Merck's (MRK) verubecestat, the study remains blinded and variability on the primary endpoint can stem from a host of reasons, not all of them bad, Raymond tells investors in a research note titled "Aducanumab P3 Upsizing Doesn't Tell Us Much." The analyst does not think yesterday's news says much about the chances for an interim analysis or about aducanumab's efficacy profile. He keeps an Overweight rating on Biogen with a $407 price target.
02/15/18
02/15/18
UPGRADE
Target $78

Overweight
Bristol-Myers upgraded on immuno-oncology growth prospects at Morgan Stanley
As previously reported, Morgan Stanley analyst David Risinger upgraded Bristol-Myers (BMY) to Overweight from Equal Weight as he has become more optimistic on the immuno-oncology Opdivo + Yervoy combo in first-line lung cancer, which he notes is the largest cancer market. After the analyst reviewed combo toxicity in select combo studies with similar dosing as Bristol's CM-227 and compared cross trial against Merck's (MRK) Keynote-021G trial that tested Keytruda + chemo, he concluded that discontinuation rates due to side effects appear roughly comparable and now thinks Opdivo + Yervoy toxicity in lung cancer is likely to be acceptable. Risinger raised his price target on Bristol-Myers shares to $78 from $63.
03/02/18
LEER
03/02/18
NO CHANGE
Target $29
LEER
Outperform
Leerink ups Heron Therapeutics target to $29 after competitor setback
Leerink analyst Ami Fadia raised her price target for Heron Therapeutics (HRTX) to $29 from $27 after Tesaro (TSRO) announced earlier this week that it has withdrawn all promotional support for IV Varubi, based on numerous reports of anaphylaxis. Heron's Cinvanti, Tesaro's Varubi and Merck's (MRK) Emend are the only three branded NK-1 antagonists in the market today for chemo induced nausea and vomiting, Fadia tells investors in a research note. With Emend expected to go generic soon, Cinvanti will be the sole marketed branded agent, the analyst adds. She increased her 2023 estimate for Cinvanti from $150M to just under $200M and keeps an Outperform rating on Heron Therapeutics. The analyst continues to see upside for the stock ahead of the two Phase 3 trials for HTX-011 expected to read out in Q2.

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COP

ConocoPhillips

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FSUMY

Fortescue Metal

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PepsiCo

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Dish

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MTW

Manitowoc

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Caterpillar

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-2.68 (-1.90%)

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Caterpillar

$138.06

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DE

Deere

$136.19

-1.41 (-1.02%)

GNRC

Generac

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CZR

Caesars

$11.63

0.075 (0.65%)

19:33
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Conference/Events
Morgan Stanley telecom analyst to hold an analyst/industry conference call »

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CAAP

Corporacion America Airport

$9.87

0.08 (0.82%)

19:11
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Hot Stocks
Corporacion America Airport reports June passenger traffic up 5.8% »

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RIO

Rio Tinto

$53.64

-0.36 (-0.67%)

19:08
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CDMO

Avid Bioservices

$4.46

-0.19 (-4.09%)

, IGT

International Game

$24.39

-0.5 (-2.01%)

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CDMO

Avid Bioservices

$4.46

-0.19 (-4.09%)

IGT

International Game

$24.39

-0.5 (-2.01%)

BGS

B&G Foods

$29.80

-0.2 (-0.67%)

AG

First Majestic

$7.44

-0.265 (-3.44%)

NFLX

Netflix

$400.24

4.32 (1.09%)

ROKU

Roku

$48.27

-0.52 (-1.07%)

AVEO

Aveo Pharmaceuticals

$2.85

-0.055 (-1.90%)

EOLS

Evolus

$25.08

-1.12 (-4.27%)

TRQ

Turquoise Hill

$2.94

0.11 (3.89%)

CARB

Carbonite

$38.40

-0.1 (-0.26%)

RDFN

Redfin

$23.99

0.46 (1.96%)

NAKD

Naked Brand Group

$4.95

-0.15 (-2.94%)

MTW

Manitowoc

$26.99

-0.52 (-1.89%)

AMZN

Amazon.com

$1,822.02

9.02 (0.50%)

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T

AT&T

$31.90

0.24 (0.76%)

18:58
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Warner Bros.' 'Aquaman' film out in theaters December 21 »

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SBGI

Sinclair Broadcast

$29.10

-3.9 (-11.82%)

, TRCO

Tribune Media

$32.05

-6.55 (-16.97%)

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Sinclair Broadcast 'shocked and disappointed' by FCC Chairman Pai's statement »

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SBGI

Sinclair Broadcast

$29.10

-3.9 (-11.82%)

TRCO

Tribune Media

$32.05

-6.55 (-16.97%)

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DE

Deere

$136.19

-1.41 (-1.02%)

18:49
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CAT

Caterpillar

$138.06

-2.68 (-1.90%)

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RIO

Rio Tinto

$53.64

-0.36 (-0.67%)

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NFLX

Netflix

$400.24

4.32 (1.09%)

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Breaking Hot Stocks news story on Netflix »

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NFLX

Netflix

$400.24

4.32 (1.09%)

18:39
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  • 16

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IBM

IBM

$145.43

-0.48 (-0.33%)

, GRPN

Groupon

$4.70

0.025 (0.53%)

18:32
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Periodicals
IBM seeks $166.5M in damages from Groupon in patent lawsuit, Bloomberg says »

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IBM

IBM

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GRPN

Groupon

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LGF.A

Lionsgate

$25.33

-0.58 (-2.24%)

, LGF.B

Lionsgate

$23.85

-0.69 (-2.81%)

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LGF.A

Lionsgate

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Lionsgate

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  • 09

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GNRC

Generac

$52.40

-0.585 (-1.10%)

18:30
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MTW

Manitowoc

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-0.52 (-1.89%)

18:29
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NFLX

Netflix

$400.24

4.32 (1.09%)

18:27
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Breaking Hot Stocks news story on Netflix »

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NFLX

Netflix

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Netflix says far from reaching a limit on pricing in India »

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  • 16

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FCPT

Four Corners Property Trust

$24.83

-0.06 (-0.24%)

18:24
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Four Corners Property Trust acquires Buffalo Wild Wings restaurant for $3.6M »

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ASOMY

Asos

$0.00

(0.00%)

18:14
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NFLX

Netflix

$400.24

4.32 (1.09%)

18:11
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Breaking Hot Stocks news story on Netflix »

Netflix says adoption of…

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