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NLNK

NewLink Genetics

$4.20

-3.12 (-42.62%)

, INCY

Incyte

$64.02

-19.05 (-22.93%)

05:15
04/09/18
04/09
05:15
04/09/18
05:15

NewLink Genetics downgraded to Hold with $4 target at Jefferies

Jefferies analyst Biren Amin late Friday downgraded NewLink Genetics (NLNK) to Hold from Buy and cut his price target for the shares to $4 from $17. The stock closed Friday down 43%, or $3.12, to $4.20. The analyst does not see a scenario in which the company's IDO inhibitor can avoid the same fate as Incyte and Merck's epacadostat plus Keytruda failed study.

NLNK

NewLink Genetics

$4.20

-3.12 (-42.62%)

INCY

Incyte

$64.02

-19.05 (-22.93%)

MRK

Merck

$53.36

-1.17 (-2.15%)

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    Oct

NLNK NewLink Genetics
$4.20

-3.12 (-42.62%)

04/09/18
BARD
04/09/18
DOWNGRADE
BARD
Neutral
NewLink Genetics downgraded to Neutral from Outperform at Baird
04/06/18
JEFF
04/06/18
DOWNGRADE
JEFF
Hold
NewLink Genetics downgraded to Hold from Buy at Jefferies
04/06/18
BOFA
04/06/18
DOWNGRADE
BOFA
Neutral
NewLink Genetics downgraded to Neutral from Buy at BofA/Merrill
04/06/18
RHCO
04/06/18
DOWNGRADE
RHCO
Hold
NewLink Genetics downgraded to Hold from Buy at SunTrust
INCY Incyte
$64.02

-19.05 (-22.93%)

04/06/18
04/06/18
DOWNGRADE

On The Fly: Top five analyst downgrades
Catch up on today's top five analyst downgrades with this list compiled by The Fly: 1. Incyte (INCY) downgraded to Neutral from Buy at Guggenheim and to Market Perform from Outperform at William Blair. 2. Ormat Technologies (ORA) downgraded to Perform from Outperform at Oppenheimer with analyst Noah Kaye citing valuation. 3. Sprague Resources (SRLP) downgraded to Underweight from Neutral at JPMorgan with analyst Andrew Burd citing the stock's year-to-date outperformance for the downgrade. 4. Banc of California (BANC) downgraded to Underperform from Neutral at BofA/Merrill with analyst Ebrahim Poonwala saying the company's new management team is working towards achieving its long-term strategic targets but is cautious on elevated execution risk given the balance sheet overhaul and lower quality deposit base. 5. Xilinx (XLNX) downgraded to Underweight from Neutral at JPMorgan with analyst Harlan Sur saying he believes multiple compression is likely with basestation deployment in China likely to decline in 2018. This list is just a portion of The Fly's full analyst coverage. To see The Fly's full Street Research coverage, click here.
04/06/18
CANT
04/06/18
NO CHANGE
Target $26
CANT
Overweight
Cantor says premature to assume NewLink trial will fail like Incyte's
NewLink Genetics' (NLNK) indoximod, which acts as a tryptophan mimetic rather than an IDO enzymatic inhibitor, has shown differentiated data versus Incyte's (INCY) epacadostat, Cantor Fitzgerald analyst Mara Goldstein tells investors in a research note. NewLink is trading down 37.5%, or $2.75, to $4.57 after Incyte announced that its ECHO-301 study of epacadostat plus Merck's (MRK) Keytruda versus Keytruda alone was unsuccessful in treating advanced melanoma. Goldstein thinks assuming failure of indoximod "may be premature," but she acknowledges that NewLink shares are likely to be pressured with the company's Phase III trial end likely over a year away. If indoximod is truly differentiated, however, NewLink shares will be higher than $26 given the "now likely limited competition," Goldstein contends. She reiterates an Overweight rating on the shares with a $26 price target.
04/06/18
MZHO
04/06/18
NO CHANGE
Target $103
MZHO
Buy
Mizuho says failure of Incyte's epacadostat ups chances of Nektar takeover
Mizuho analyst Difei Yang raised her price target on Nektar Therapeutics (NKTR) to $103 from $89 after Incyte (INCY) announced this morning the failure of epacadostat in combination with Merck's (MRK) Keytruda in a phase 3 study in melanoma patients. Recent clinical data presented by Nektar reinforced her view of NKTR-214 as one of the most impressive combo agent for checkpoint inhibitors, said Yang, who believes that the failure of epacadostat raises the possibility of a takeout by Bristol-Myers (BMY) in the coming months. She maintains a Buy rating on Nektar shares, which are down 8.5% to $92.75 in afternoon trading.
04/06/18
GUGG
04/06/18
DOWNGRADE
GUGG
Neutral
Incyte downgraded to Neutral from Buy at Guggenheim
MRK Merck
$53.36

-1.17 (-2.15%)

04/06/18
WBLR
04/06/18
DOWNGRADE
WBLR
Market Perform
William Blair downgrades Incyte after metastatic melanoma study failure
William Blair analyst Katherine Xu downgraded Incyte (INCY) to Market Perform from Outperform after the company and partner Merck (MRK) announced that ECHO-301 did not meet one of the primary endpoints of improving progression-free survival and that overall survival, the other co-primary endpoint, was not expected to be met either. After taking epacadostat out of her model, the analyst's fair value estimate for Incyte drops to $88 from $170. The stock in premarket trading is down 21%, or $17.08, to $65.99. It is unclear whether the biomarker data derived from ECHO-301 could guide other Phase III studies, and whether the other Phase III studies are to continue, Xu tells investors in a research note. She sees the next key catalysts for Incyte shares as the baricitinib advisory panel on April 23, and data from Jakafi Phase II pivotal REACH1 study in steroid-refractory acute graft-versus-host disease in the first half 2018.
04/05/18
04/05/18
UPGRADE

On The Fly: Top five analyst upgrades
Catch up on today's top five analyst upgrades with this list compiled by The Fly: 1. Merck (MRK) upgraded to Overweight from Equal Weight at Barclays with analyst Geoffrey Meacham saying he believes the company will continue to take share in first-line lung cancer, driven by positive KN-189 and KN-042 data. 2. Acuity Brands (AYI) upgraded to Outperform from Market Perform at JMP Securities with analyst Joseph Osha saying he believes the stock is finally trading at a "reasonable valuation based on reasonable expectations." 3. AMD (AMD) upgraded to Buy from Hold at Stifel with analyst Kevin Cassidy citing valuation and the company's margin expansion potential. 4. Tiffany (TIF) upgraded to Buy from Hold at Loop Capital with analyst Laura Champine saying her initial meeting with the company's new CEO Alessandro Bogliogo added to her confidence. 5. Citi (C) and Wells Fargo (WFC) were upgraded to Buy from Neutral at UBS. This list is just a portion of The Fly's full analyst coverage. To see The Fly's full Street Research coverage, click here.

TODAY'S FREE FLY STORIES

FB

Facebook

$159.66

-6.19 (-3.73%)

20:37
04/24/18
04/24
20:37
04/24/18
20:37
Periodicals
Facebook replaces Erin Egan, the head of policy for U.S., NYT reports »

Fecebook head of U.S.…

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    Apr

BOOT

Boot Barn

$19.76

0.305 (1.57%)

20:33
04/24/18
04/24
20:33
04/24/18
20:33
Hot Stocks
Boot Barn acquires Lone Star Western & Casual LLC assets, terms not disclosed »

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BA

Boeing

$329.00

-9.52 (-2.81%)

, CMCSA

Comcast

$33.33

-0.53 (-1.57%)

20:25
04/24/18
04/24
20:25
04/24/18
20:25
Earnings
Notable companies reporting before tomorrow's open »

Notable companies…

BA

Boeing

$329.00

-9.52 (-2.81%)

CMCSA

Comcast

$33.33

-0.53 (-1.57%)

CMCSK

Comcast

TMO

Thermo Fisher

$213.13

-3.17 (-1.47%)

GD

General Dynamics

$222.04

-4.05 (-1.79%)

NOC

Northrop Grumman

$341.00

-15.06 (-4.23%)

ANTM

Anthem

$225.08

-2.11 (-0.93%)

NSC

Norfolk Southern

$134.92

-2.83 (-2.05%)

BSX

Boston Scientific

$28.43

-0.39 (-1.35%)

SIRI

SiriusXM

$6.27

-0.06 (-0.95%)

TROW

T. Rowe Price

$107.42

-1.23 (-1.13%)

TWTR

Twitter

$30.48

-0.74 (-2.37%)

ROK

Rockwell Automation

$161.97

-7.185 (-4.25%)

DPS

Dr Pepper Snapple

$118.87

-1 (-0.83%)

STM

STMicroelectronics

$21.30

0.35 (1.67%)

HES

Hess Corp.

$57.71

-0.83 (-1.42%)

NDAQ

Nasdaq

$86.27

-0.65 (-0.75%)

VIAB

Viacom

$30.91

-0.14 (-0.45%)

OC

Owens Corning

$75.79

-2.32 (-2.97%)

GT

Goodyear Tire

$26.86

-0.14 (-0.52%)

NYCB

New York Community Bancorp

$12.97

0.115 (0.89%)

03/08/13
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03/06/13
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FBMS

First Bancshares

$31.90

-0.1 (-0.31%)

20:18
04/24/18
04/24
20:18
04/24/18
20:18
Earnings
First Bancshares reports Q1 adjusted EPS 46c, consensus 48c »

Reports Q1 revenue…

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    Sep

NVS

Novartis

$77.00

-0.595 (-0.77%)

, GILD

Gilead

$72.71

-1.27 (-1.72%)

20:03
04/24/18
04/24
20:03
04/24/18
20:03
Periodicals
CAR-T blood cancer treatments may be Medicare-eligible, Bloomberg says »

Customized blood cancer…

NVS

Novartis

$77.00

-0.595 (-0.77%)

GILD

Gilead

$72.71

-1.27 (-1.72%)

03/08/13
Wedge Partners
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Credit Suisse
03/06/13
Citigroup
03/06/13
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    Jun

LPL

LG Display

$11.19

-0.21 (-1.84%)

19:50
04/24/18
04/24
19:50
04/24/18
19:50
Earnings
LG Display reports Q1 Net loss KRW 49B vs. net profit KRW 679B last year »

Reports Q1 revenue KRW…

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LLY

Eli Lilly

$80.09

-0.16 (-0.20%)

, CG

Carlyle Group

$20.65

-0.35 (-1.67%)

19:45
04/24/18
04/24
19:45
04/24/18
19:45
Periodicals
Eli Lilly animal health business seeing private equity interest, Bloomberg says »

Bain Capital, Advent…

LLY

Eli Lilly

$80.09

-0.16 (-0.20%)

CG

Carlyle Group

$20.65

-0.35 (-1.67%)

03/08/13
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03/06/13
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03/06/13
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DOC

Physicians Realty Trust

$14.67

0.185 (1.28%)

19:40
04/24/18
04/24
19:40
04/24/18
19:40
Downgrade
Physicians Realty Trust rating change  »

Physicians Realty Trust…

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LFC

China Life Insurance

19:38
04/24/18
04/24
19:38
04/24/18
19:38
Upgrade
China Life Insurance rating change  »

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HTA

Healthcare Trust

19:37
04/24/18
04/24
19:37
04/24/18
19:37
Downgrade
Healthcare Trust rating change  »

Healthcare Trust…

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HR

Healthcare Realty Trust

$27.10

0.325 (1.21%)

19:37
04/24/18
04/24
19:37
04/24/18
19:37
Downgrade
Healthcare Realty Trust rating change  »

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GOOGL

Alphabet Class A

$1,022.98

-50.08 (-4.67%)

19:37
04/24/18
04/24
19:37
04/24/18
19:37
Upgrade
Alphabet Class A rating change  »

Alphabet upgraded to Buy…

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T

AT&T

$35.00

0.11 (0.32%)

, TWX

Time Warner

$96.02

-0.32 (-0.33%)

19:25
04/24/18
04/24
19:25
04/24/18
19:25
Periodicals
AT&T lawyer grills star U.S. witness over data in pay-TV study, Bloomberg says »

The U.S.…

T

AT&T

$35.00

0.11 (0.32%)

TWX

Time Warner

$96.02

-0.32 (-0.33%)

03/08/13
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03/06/13
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  • 24

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SHPG

Shire

$164.05

3.97 (2.48%)

, TKPYY

Takeda Pharmaceutical

19:15
04/24/18
04/24
19:15
04/24/18
19:15
Hot Stocks
Shire confirms receipt of revised GBP46B stock and cash proposal from Takeda »

The board of Shire (SHPG)…

SHPG

Shire

$164.05

3.97 (2.48%)

TKPYY

Takeda Pharmaceutical

03/08/13
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  • 21

    Dec

CREE

Cree

$39.39

-1 (-2.48%)

, SIX

Six Flags

$59.17

-1.62 (-2.66%)

19:02
04/24/18
04/24
19:02
04/24/18
19:02
Hot Stocks
On The Fly: After Hours Movers »

UP AFTER EARNINGS: Cree…

CREE

Cree

$39.39

-1 (-2.48%)

SIX

Six Flags

$59.17

-1.62 (-2.66%)

TXN

Texas Instruments

$98.33

0.25 (0.25%)

USNA

USANA

$95.93

0.175 (0.18%)

MKSI

MKS Instruments

$102.85

-3.35 (-3.15%)

SVU

Supervalu

$14.61

-0.02 (-0.14%)

IRBT

iRobot

$59.10

-0.85 (-1.42%)

DDR

DDR Corp.

$6.68

0.025 (0.38%)

IPHI

Inphi

$31.46

1.1 (3.62%)

HA

Hawaiian Holdings

$39.20

-0.3 (-0.76%)

SHPG

Shire

$164.05

3.97 (2.48%)

KN

Knowles

$11.01

-0.575 (-4.97%)

TER

Teradyne

$41.50

1.06 (2.62%)

EW

Edwards Lifesciences

$134.63

-2.59 (-1.89%)

DLB

Dolby

$65.85

-1.4 (-2.08%)

WYNN

Wynn Resorts

$189.70

-3.54 (-1.83%)

COF

Capital One

$97.41

-0.115 (-0.12%)

SGMO

Sangamo

$17.85

-0.3 (-1.65%)

MRTX

Mirati Therapeutics

$28.25

-0.15 (-0.53%)

03/08/13
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    Apr

AMX

America Movil, also tag AMOV

$18.62

-0.15 (-0.80%)

, AMOV

America Movil, also tag AMX

$18.50

-0.27 (-1.44%)

19:02
04/24/18
04/24
19:02
04/24/18
19:02
Earnings
America Movil reports Q1 net profit MXN18.1B vs. MXN35.9B last year »

Reports Q1 revenue…

AMX

America Movil, also tag AMOV

$18.62

-0.15 (-0.80%)

AMOV

America Movil, also tag AMX

$18.50

-0.27 (-1.44%)

03/08/13
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AEP

American Electric

$68.89

0.46 (0.67%)

, WMT

Walmart

$86.51

0.41 (0.48%)

18:30
04/24/18
04/24
18:30
04/24/18
18:30
Hot Stocks
PSO, OEIC, Walmart reach settlement pact on proposed Wind Catcher project »

Public Service Company of…

AEP

American Electric

$68.89

0.46 (0.67%)

WMT

Walmart

$86.51

0.41 (0.48%)

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    Jun

AMGN

Amgen

$171.91

-2.75 (-1.57%)

18:05
04/24/18
04/24
18:05
04/24/18
18:05
Hot Stocks
Breaking Hot Stocks news story on Amgen »

Amgen reports Q1 Repatha…

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AMGN

Amgen

$171.91

-2.75 (-1.57%)

18:03
04/24/18
04/24
18:03
04/24/18
18:03
Hot Stocks
Amgen CEO says Q1 performance driven by new, recently launched products »

"Amgen's strong…

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NWE

NorthWestern

$54.36

0.315 (0.58%)

18:03
04/24/18
04/24
18:03
04/24/18
18:03
Earnings
Breaking Earnings news story on NorthWestern »

NorthWestern reports Q1…

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NWE

NorthWestern

$54.36

0.315 (0.58%)

18:01
04/24/18
04/24
18:01
04/24/18
18:01
Earnings
NorthWestern reports Q1 EPS $1.18, consensus $1.17 »

Reports Q1 revenue…

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FR

First Industrial Realty

$29.62

0.315 (1.07%)

18:00
04/24/18
04/24
18:00
04/24/18
18:00
Earnings
First Industrial Realty reports Q1 FFO 38c, consensus 38c »

Reports Q1 revenue…

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NVT

nVent Electric

, KN

Knowles

$11.01

-0.575 (-4.97%)

17:59
04/24/18
04/24
17:59
04/24/18
17:59
Hot Stocks
S&P announces changes to S&P MidCap 400, S&P SmallCap 600 indices »

nVent Electric (NVT) will…

NVT

nVent Electric

KN

Knowles

$11.01

-0.575 (-4.97%)

DHX

DHI Group

PNR

Pentair

$67.14

-2.13 (-3.07%)

03/08/13
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VICR

Vicor Corporation

$29.25

-0.6 (-2.01%)

17:57
04/24/18
04/24
17:57
04/24/18
17:57
Earnings
Vicor reports Q1 EPS 10c vs.(2c) in same quarter last year »

Vicor reports Q1 net…

03/08/13
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  • 24

    Apr

SMBK

SmartFinancial

17:53
04/24/18
04/24
17:53
04/24/18
17:53
Earnings
SmartFinancial reports Q1 EPS 30c, consensus 34c »

Billy Carroll, President…

03/08/13
Wedge Partners
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