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MRK

Merck

$53.36

-1.17 (-2.15%)

06:46
04/09/18
04/09
06:46
04/09/18
06:46

Merck: Phase 3 KEYNOTE-042 trial met primary endpoint of overall survival

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MRK Merck
$53.36

-1.17 (-2.15%)

04/06/18
WBLR
04/06/18
DOWNGRADE
WBLR
Market Perform
William Blair downgrades Incyte after metastatic melanoma study failure
William Blair analyst Katherine Xu downgraded Incyte (INCY) to Market Perform from Outperform after the company and partner Merck (MRK) announced that ECHO-301 did not meet one of the primary endpoints of improving progression-free survival and that overall survival, the other co-primary endpoint, was not expected to be met either. After taking epacadostat out of her model, the analyst's fair value estimate for Incyte drops to $88 from $170. The stock in premarket trading is down 21%, or $17.08, to $65.99. It is unclear whether the biomarker data derived from ECHO-301 could guide other Phase III studies, and whether the other Phase III studies are to continue, Xu tells investors in a research note. She sees the next key catalysts for Incyte shares as the baricitinib advisory panel on April 23, and data from Jakafi Phase II pivotal REACH1 study in steroid-refractory acute graft-versus-host disease in the first half 2018.
04/06/18
CANT
04/06/18
NO CHANGE
Target $26
CANT
Overweight
Cantor says premature to assume NewLink trial will fail like Incyte's
NewLink Genetics' (NLNK) indoximod, which acts as a tryptophan mimetic rather than an IDO enzymatic inhibitor, has shown differentiated data versus Incyte's (INCY) epacadostat, Cantor Fitzgerald analyst Mara Goldstein tells investors in a research note. NewLink is trading down 37.5%, or $2.75, to $4.57 after Incyte announced that its ECHO-301 study of epacadostat plus Merck's (MRK) Keytruda versus Keytruda alone was unsuccessful in treating advanced melanoma. Goldstein thinks assuming failure of indoximod "may be premature," but she acknowledges that NewLink shares are likely to be pressured with the company's Phase III trial end likely over a year away. If indoximod is truly differentiated, however, NewLink shares will be higher than $26 given the "now likely limited competition," Goldstein contends. She reiterates an Overweight rating on the shares with a $26 price target.
04/06/18
MZHO
04/06/18
NO CHANGE
Target $103
MZHO
Buy
Mizuho says failure of Incyte's epacadostat ups chances of Nektar takeover
Mizuho analyst Difei Yang raised her price target on Nektar Therapeutics (NKTR) to $103 from $89 after Incyte (INCY) announced this morning the failure of epacadostat in combination with Merck's (MRK) Keytruda in a phase 3 study in melanoma patients. Recent clinical data presented by Nektar reinforced her view of NKTR-214 as one of the most impressive combo agent for checkpoint inhibitors, said Yang, who believes that the failure of epacadostat raises the possibility of a takeout by Bristol-Myers (BMY) in the coming months. She maintains a Buy rating on Nektar shares, which are down 8.5% to $92.75 in afternoon trading.
04/09/18
JEFF
04/09/18
DOWNGRADE
Target $4
JEFF
Hold
NewLink Genetics downgraded to Hold with $4 target at Jefferies
Jefferies analyst Biren Amin late Friday downgraded NewLink Genetics (NLNK) to Hold from Buy and cut his price target for the shares to $4 from $17. The stock closed Friday down 43%, or $3.12, to $4.20. The analyst does not see a scenario in which the company's IDO inhibitor can avoid the same fate as Incyte and Merck's epacadostat plus Keytruda failed study.

TODAY'S FREE FLY STORIES

AKRX

Akorn

$19.68

0.31 (1.60%)

, FSNUY

Fresenius SE

14:08
04/22/18
04/22
14:08
04/22/18
14:08
Hot Stocks
Fresenius terminates merger agreement with Akorn over data breaches »

Fresenius (FSNUY) decided…

AKRX

Akorn

$19.68

0.31 (1.60%)

FSNUY

Fresenius SE

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LEVB

Level Brands

$5.15

0.25 (5.10%)

12:20
04/22/18
04/22
12:20
04/22/18
12:20
Conference/Events
Level Brands CEO Sumichrast interview to air on The RedChip Money Report »

Marty Sumichrast,…

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LEVB

Level Brands

$5.15

0.25 (5.10%)

04:55
04/22/18
04/22
04:55
04/22/18
04:55
Conference/Events
Level Brands CEO Sumichrast interview to air on The RedChip Money Report »

Marty Sumichrast,…

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04:55
04/22/18
04/22
04:55
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04:55
Conference/Events
International Monetary Fund & World Bank Group to co-host an annual meeting »

2018 Spring Meeting will…

CGNT

Cogentix Medical

$3.84

-0.005 (-0.13%)

19:21
04/21/18
04/21
19:21
04/21/18
19:21
Hot Stocks
Laborie Medical announces completion of tender offer for Cogentix Medical »

Laborie Medical…

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TSG

The Stars Group

$29.35

0.4 (1.38%)

, SKYAY

Sky

18:31
04/21/18
04/21
18:31
04/21/18
18:31
Hot Stocks
The Stars Group to acquire Sky Betting & Gaming for $4.7B »

The Stars Group (TSG)…

TSG

The Stars Group

$29.35

0.4 (1.38%)

SKYAY

Sky

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LUV

Southwest

$54.76

-0.02 (-0.04%)

18:22
04/21/18
04/21
18:22
04/21/18
18:22
Hot Stocks
Southwest responds to Emergency Airworthiness Directive »

Southwest Airlines said…

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TPR

Tapestry

$53.03

-0.255 (-0.48%)

16:17
04/21/18
04/21
16:17
04/21/18
16:17
Periodicals
Tapestry could see more stock gains, Barron's says »

In a follow-up story,…

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DAL

Delta Air Lines

$55.40

0.34 (0.62%)

, GM

General Motors

$37.61

-0.16 (-0.42%)

16:05
04/21/18
04/21
16:05
04/21/18
16:05
Periodicals
Delta, GM look cheap, with growth potential, Barron's says »

While a solid start to…

DAL

Delta Air Lines

$55.40

0.34 (0.62%)

GM

General Motors

$37.61

-0.16 (-0.42%)

GT

Goodyear Tire

$27.00

0.06 (0.22%)

LNC

Lincoln National

$71.59

-0.04 (-0.06%)

03/08/13
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GIS

General Mills

$43.41

-0.61 (-1.39%)

15:57
04/21/18
04/21
15:57
04/21/18
15:57
Periodicals
General Mills shares fall to 'bargain territory,' Barron's says »

General Mills has fallen…

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CCL

Carnival

$65.88

0.82 (1.26%)

, RCL

Royal Caribbean

$119.11

1.18 (1.00%)

15:51
04/21/18
04/21
15:51
04/21/18
15:51
Periodicals
Cruise operators can offer 'nice' yields, solid dividend growth, Barron's says »

Cruise operators, like…

CCL

Carnival

$65.88

0.82 (1.26%)

RCL

Royal Caribbean

$119.11

1.18 (1.00%)

NCLH

Norwegian Cruise Line

$55.65

0.71 (1.29%)

DIS

Disney

$100.24

-0.64 (-0.63%)

03/08/13
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GOOG

Alphabet

$1,072.73

-15.18 (-1.40%)

, GOOGL

Alphabet Class A

$1,076.64

-12.83 (-1.18%)

15:42
04/21/18
04/21
15:42
04/21/18
15:42
Periodicals
Tech giants may make own custom chips to get edge on one another, Barron's says »

There has been a tension…

GOOG

Alphabet

$1,072.73

-15.18 (-1.40%)

GOOGL

Alphabet Class A

$1,076.64

-12.83 (-1.18%)

AMZN

Amazon.com

$1,527.39

-29.57 (-1.90%)

FB

Facebook

$166.29

-1.82 (-1.08%)

AAPL

Apple

$165.71

-7.08 (-4.10%)

MSFT

Microsoft

$95.01

-1.1 (-1.14%)

BIDU

Baidu

$232.38

-4.73 (-1.99%)

BABA

Alibaba

$179.07

-2.14 (-1.18%)

INTC

Intel

$51.53

-0.68 (-1.30%)

NVDA

Nvidia

$228.74

-0.21 (-0.09%)

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EPD

Enterprise Products

$26.60

-0.03 (-0.11%)

, MMP

Magellan Midstream

$65.16

-0.755 (-1.15%)

15:32
04/21/18
04/21
15:32
04/21/18
15:32
Periodicals
MPL valuations look cheap, Barron's says »

Master limited…

EPD

Enterprise Products

$26.60

-0.03 (-0.11%)

MMP

Magellan Midstream

$65.16

-0.755 (-1.15%)

MPLX

MPLX

PAA

Plains All American

$24.68

0.42 (1.73%)

03/08/13
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AMZN

Amazon.com

$1,527.39

-29.57 (-1.90%)

, TWX

Time Warner

$96.23

-0.34 (-0.35%)

08:34
04/21/18
04/21
08:34
04/21/18
08:34
Periodicals
Trump's tweets politicize U.S. markets, Barron's says »

With President Donald…

AMZN

Amazon.com

$1,527.39

-29.57 (-1.90%)

TWX

Time Warner

$96.23

-0.34 (-0.35%)

T

AT&T

$34.67

-0.15 (-0.43%)

MYL

Mylan

$40.73

-0.08 (-0.20%)

03/08/13
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FB

Facebook

$166.29

-1.82 (-1.08%)

, AAPL

Apple

$165.71

-7.08 (-4.10%)

08:15
04/21/18
04/21
08:15
04/21/18
08:15
Periodicals
Facebook, Apple embody new tech divide, Barron's says »

For several years now,…

FB

Facebook

$166.29

-1.82 (-1.08%)

AAPL

Apple

$165.71

-7.08 (-4.10%)

AMZN

Amazon.com

$1,527.39

-29.57 (-1.90%)

NFLX

Netflix

$327.57

-5.12 (-1.54%)

GOOG

Alphabet

$1,072.73

-15.18 (-1.40%)

GOOGL

Alphabet Class A

$1,076.64

-12.83 (-1.18%)

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AMZN

Amazon.com

$1,527.39

-29.57 (-1.90%)

, ACIA

Acacia Communications

$27.54

1.04 (3.92%)

08:00
04/21/18
04/21
08:00
04/21/18
08:00
Hot Stocks
Week in review: How Trump's policies moved stocks »

Catch up on the top…

AMZN

Amazon.com

$1,527.39

-29.57 (-1.90%)

ACIA

Acacia Communications

$27.54

1.04 (3.92%)

OCLR

Oclaro

$8.27

0.08 (0.98%)

NOK

Nokia

$5.96

0.125 (2.14%)

NPTN

NeoPhotonics

$6.05

-0.01 (-0.17%)

LITE

Lumentum

$58.90

-1.05 (-1.75%)

FNSR

Finisar

$15.43

0.045 (0.29%)

MSFT

Microsoft

$95.01

-1.1 (-1.14%)

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  • 12

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04:55
04/21/18
04/21
04:55
04/21/18
04:55
Conference/Events
International Monetary Fund & World Bank Group to co-host an annual meeting »

2018 Spring Meeting will…

SPX

S&P 500

, SPY

SPDR S&P 500 ETF Trust

$266.66

-2.18 (-0.81%)

18:08
04/20/18
04/20
18:08
04/20/18
18:08
Periodicals
North Korea to suspend nuclear and ICBM tests, Bloomberg reports »

North Korea also plans to…

SPX

S&P 500

SPY

SPDR S&P 500 ETF Trust

$266.66

-2.18 (-0.81%)

03/08/13
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ADM

Archer Daniels

$45.50

-0.295 (-0.64%)

, BG

Bunge

$73.72

-1.935 (-2.56%)

18:03
04/20/18
04/20
18:03
04/20/18
18:03
Periodicals
Archer Daniels, Bunge talks end without merger deal, Bloomberg reports »

Advanced merger…

ADM

Archer Daniels

$45.50

-0.295 (-0.64%)

BG

Bunge

$73.72

-1.935 (-2.56%)

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  • 02

    May

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    May

CE

Celanese

$111.69

0.56 (0.50%)

18:02
04/20/18
04/20
18:02
04/20/18
18:02
Hot Stocks
Celanese announces price increases in Asia »

Celanese will increase…

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  • 01

    May

  • 30

    May

IOTS

Adesto Technologies

$8.65

-0.2 (-2.26%)

17:33
04/20/18
04/20
17:33
04/20/18
17:33
Hot Stocks
Breaking Hot Stocks news story on Adesto Technologies »

180 Degree Capital lowers…

03/08/13
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  • 23

    May

SIGM

Sigma Designs

$6.30

0.1 (1.61%)

17:22
04/20/18
04/20
17:22
04/20/18
17:22
Hot Stocks
Sigma Designs to delay filing Annual Report on Form 10-K »

Sigma Designs is unable…

03/08/13
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BRK.A

Berkshire Hathaway

$300,140.00

-260 (-0.09%)

, BRK.B

Berkshire Hathaway

$200.09

-0.32 (-0.16%)

17:22
04/20/18
04/20
17:22
04/20/18
17:22
Hot Stocks
Breaking Hot Stocks news story on Berkshire Hathaway, Berkshire Hathaway, Torchmark »

Berkshire Hathaway…

BRK.A

Berkshire Hathaway

$300,140.00

-260 (-0.09%)

BRK.B

Berkshire Hathaway

$200.09

-0.32 (-0.16%)

TMK

Torchmark

$87.22

0.02 (0.02%)

03/08/13
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03/06/13
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SMHI

SEACOR Marine Holdings

$22.90

-0.86 (-3.62%)

, CG

Carlyle Group

$20.85

0.15 (0.72%)

17:17
04/20/18
04/20
17:17
04/20/18
17:17
Syndicate
SEACOR Marine Holdings announces $56.9M private placement of common stock »

SEACOR Marine Holdings…

SMHI

SEACOR Marine Holdings

$22.90

-0.86 (-3.62%)

CG

Carlyle Group

$20.85

0.15 (0.72%)

03/08/13
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03/08/13
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03/06/13
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03/06/13
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  • 12

    Jun

AVAV

AeroVironment

$56.66

-0.15 (-0.26%)

17:12
04/20/18
04/20
17:12
04/20/18
17:12
Hot Stocks
AeroVironment awarded $44.7M U.S. Army contract modification »

AeroVironment was awarded…

03/08/13
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  • 09

    May

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