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GTXI

GTx

$17.90

-0.56 (-3.03%)

07:01
04/09/18
04/09
07:01
04/09/18
07:01

GTx announces early completion of patient enrollment in ASTRID trial

GTx, Inc. announced that it has completed patient enrollment several months ahead of schedule in its placebo-controlled, Phase 2 clinical trial of enobosarm in postmenopausal women with stress urinary incontinence. The ASTRID trial enrolled 493 women at over 60 clinical trial centers across the United States. Top-line results are expected early in the fourth quarter this year. The ASTRID trial is an ongoing, placebo-controlled Phase 2 clinical trial in postmenopausal women with SUI. Top-line results from ASTRID are expected early in the fourth quarter of 2018. The rationale for evaluating enobosarm as a treatment for SUI is supported by a Phase 2 proof-of-concept clinical trial, the results of which were outlined at the Society of Urodynamics, Female Pelvic Medicine and Urogenital Reconstruction meeting in March 2018, and preclinical in vivo data demonstrating increases in pelvic floor muscle mass following treatment with GTx's SARM compounds, including enobosarm

GTXI GTx
$17.90

-0.56 (-3.03%)

11/09/17
STFL
11/09/17
INITIATION
Target $16
STFL
Buy
GTx initiated with a Buy at Stifel
Stifel analyst Adam Walsh started GTx with a Buy rating and a $16 price target, saying he believes its lead pipeline asset enobosarm in treating postmenopausal women with stress urinary incontinence has blockbuster potential. SUI is "an enormous indication with no FDA approved drugs," Walsh added.
11/09/17
11/09/17
INITIATION

On The Fly: Top five analyst initiations
Catch up on today's top five analyst initiations with this list compiled by The Fly: 1. AnaptysBio (ANAB) initiated with a Buy at Jefferies. 2. Regenxbio (RGNX) resumed with an Overweight at Morgan Stanley. 3. GTx (GTXI) initiated with a Buy at Stifel. 4. Idera Pharmaceuticals (IDRA) initiated with a Buy at H.C. Wainwright. 5. Nektar (NKTR) initiated with a Buy at Canaccord. This list is just a portion of The Fly's analyst coverage. To see The Fly's full Street Research coverage, click here.
11/21/17
BARD
11/21/17
INITIATION
Target $17
BARD
Outperform
GTx initiated with an Outperform at Baird
Baird analyst Michael Ulz initiated GTx with an Outperform rating. Based on promising activity and a well designed study, he expects positive data from the ongoing Phase 2 ASTRID study by year-end 2018 to drive meaningful upside, saying enobosarm represents a blockbuster market opportunity. Ulz has a $17 price target on GTx shares.
03/05/18
STFL
03/05/18
NO CHANGE
Target $45
STFL
Buy
GTx price target nearly tripled to $45 at Stifel after data 'steal' SUFU meeting
Stifel analyst Adam Walsh said new data presented on GTX Inc.'s phase 2 proof-of-concept study testing enobosarm in female patients stress urinary incontinence "stole the show" at the Society of Urodynamics, Female Pelvic Medicine & Urogenital Reconstruction, or SUFU, Winter Meeting this weekend. Key Opinion Leaders, or KOLs, view the off-drug durability of effect data as "highly impressive" and new MRI data "strongly supports" mechanism of action, Walsh told investors. His "informal polling" of KOLs came up with predictions on probability of ultimate enobosarm approval in SUI ranging from a low of over 50% to a high of 80%, added Walsh, who raised his price target on GTX shares to $45 from $16 and keeps a Buy rating on the stock.

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