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PRTX

Protalex

08:13
04/09/18
04/09
08:13
04/09/18
08:13

Protalex enrolls first patient in Phase 1/2 trial of PRTX-100 for ITP

Protalex announced that the company has enrolled the first of three patients in cohort four of its U.S./U.K. Phase 1/2 trial evaluating PRTX-100 for the treatment of adults with persistent/chronic Immune Thrombocytopenia, or ITP. The fourth cohort was initiated after a planned, interim analysis of safety and efficacy data from cohort three. Patient one, based in the U.S., received 12.0 micrograms/kg, double the dose used in the prior cohort of 6.0 micrograms/kg. PRTX-100 has been granted orphan drug designation in the U.S. and in Europe for the treatment of ITP. The number of clinical trial sites in the 202 Study has been expanded to the U.K to support enrollment and broaden access to the potential patient pool. The 202 Study is an open-label, dose-escalation study that can enroll patients in up to six cohorts. Under the study protocol, patients receive four weekly intravenous doses of PRTX-100 and are monitored for up to 48 weeks thereafter. The primary endpoint of the 202 Study is a platelet response to PRTX-100. Secondary endpoints include safety, immunogenicity, and pharmacokinetics. Enrollment is currently underway at several clinical sites in the U.S. and in the U.K.

TODAY'S FREE FLY STORIES

ALXN

Alexion

$105.99

-5.75 (-5.15%)

14:30
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04/20
14:30
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14:30
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Alexion analyst commentary  »

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General news
Action Economics Survey results »

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UCBI

United Community Banks

$32.40

0.27 (0.84%)

14:29
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14:29
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14:29
Syndicate
Breaking Syndicate news story on United Community Banks »

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HRTX

Heron Therapeutics

$30.40

0.6 (2.01%)

14:24
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14:24
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Heron Therapeutics analyst commentary  »

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TGI

Triumph Group

$26.05

-0.2 (-0.76%)

14:20
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14:20
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Put buying in Triumph Group »

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$NSD

NASDAQ Market Internals

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$NYE

NYSE Market Internals

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TWTR

Twitter

$31.93

0.39 (1.24%)

14:14
04/20/18
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14:14
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Twitter bans ads from Kaspersky Lab, Reuters reports »

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GE

General Electric

$14.73

0.74 (5.29%)

, WAB

Wabtec

$88.35

4.61 (5.51%)

14:07
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14:07
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14:07
Periodicals
GE explores merging transport unit with Wabtec, Reuters says »

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GE

General Electric

$14.73

0.74 (5.29%)

WAB

Wabtec

$88.35

4.61 (5.51%)

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KMB

Kimberly-Clark

$99.75

-3.59 (-3.47%)

14:05
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04/20
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14:05
Technical Analysis
Technical Earnings Preview: Kimberly-Clark near 5-year lows ahead of earnings »

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DVMT

Dell Technologies

$73.08

-0.81 (-1.10%)

14:05
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Dell Technologies call volume above normal and directionally bullish »

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  • 26

    Apr

WEN

Wendy's

$17.23

-0.165 (-0.95%)

14:02
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14:02
Hot Stocks
Wendy's announces 2020 goal of opening over 600 new restaurants globally »

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    May

14:00
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Fed Governor Brainard did not break from the gradualist mantra »

Fed Governor Brainard did…

LITE

Lumentum

$59.70

-0.25 (-0.42%)

13:55
04/20/18
04/20
13:55
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13:55
Options
Lumentum put volume heavy and directionally bearish »

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ALXN

Alexion

$104.44

-7.3 (-6.53%)

13:46
04/20/18
04/20
13:46
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13:46
Hot Stocks
Alexion drops after Brazil AG says Soliris patent made public »

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  • 26

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AKRX

Akorn

$19.61

0.24 (1.24%)

13:45
04/20/18
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13:45
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13:45
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Akorn call volume above normal and directionally bullish »

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13:45
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General news
FX Action: USD-JPY »

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TGT

Target

$70.52

-0.45 (-0.63%)

13:35
04/20/18
04/20
13:35
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13:35
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Target put volume heavy and directionally bearish »

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  • 20

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IWM

iShares Trust Russell 2000 Index Fund

$155.75

-0.65 (-0.42%)

, RUT

Russell 2000 Index

13:35
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On The Fly: Weekly technical notes for Russell 2000 »

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iShares Trust Russell 2000 Index Fund

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XLP

Consumer Staples Sector SPDR

$50.43

-0.915 (-1.78%)

, XLRE

Real Estate SPDR

$30.25

-0.25 (-0.82%)

13:33
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13:33
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On The Fly: Weekly technical notes for S&P 500 »

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XLP

Consumer Staples Sector SPDR

$50.43

-0.915 (-1.78%)

XLRE

Real Estate SPDR

$30.25

-0.25 (-0.82%)

XLK

Technology Select Sector SPDR

$66.26

-0.89 (-1.33%)

XLE

Energy Select Sector SPDR

$73.29

-0.37 (-0.50%)

XLB

S&P Select Materials SPDR

$58.95

-0.41 (-0.69%)

XLF

Financial Select Sector

$27.94

0.065 (0.23%)

SPY

SPDR S&P 500 ETF Trust

$266.75

-2.09 (-0.78%)

SPX

S&P 500

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SGMS

Scientific Games

$50.25

0.5 (1.01%)

13:25
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13:25
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13:25
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Scientific Games call volume above normal and directionally bullish »

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  • 29

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ALXN

Alexion

$110.26

-1.48 (-1.32%)

13:21
04/20/18
04/20
13:21
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13:21
Periodicals
Brazil can produce generic Soliris after breaking Alexion patent, Bloomberg says »

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  • 26

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WAB

Wabtec

$82.74

-1 (-1.19%)

, GE

General Electric

$14.46

0.47 (3.36%)

13:18
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04/20
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13:18
Hot Stocks
Wabtec rises after report of talks for GE rail business deal »

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WAB

Wabtec

$82.74

-1 (-1.19%)

GE

General Electric

$14.46

0.47 (3.36%)

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$NSD

NASDAQ Market Internals

13:17
04/20/18
04/20
13:17
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13:17
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$NYE

NYSE Market Internals

13:16
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04/20
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