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PBYI

Puma Biotechnology

$66.15

1.05 (1.61%)

05:16
04/12/18
04/12
05:16
04/12/18
05:16

Puma Biotechnology downgraded to Equal Weight from Overweight at Barclays

Barclays analyst Gena Wang downgraded Puma Biotechnology (PBYI) to Equal Weight and lowered her price target for the shares to $70 from $90. The analyst's survey of U.S. oncologists showed a lower than expected growth rate for future Nerlynx penetration. She views Nerlynx as a key value driver for Puma shares. Further, changing treatment paradigm represents some risk to the company's Phase III NALA trial, which is investigating the use of neratinib in combination with Roche's (RHHBY) Xeloda for third line treatment of metastatic HER2-positive breast cancer, Wang tells investors in a research note.

PBYI Puma Biotechnology
$66.15

1.05 (1.61%)

01/24/18
JPMS
01/24/18
NO CHANGE
Target $91
JPMS
Overweight
Puma Biotechnology price target lowered to $91 from $138 at JPMorgan
JPMorgan analyst Cory Kasimov lowered his price target for Puma Biotechnology to $91 after the Committee for Medicinal Products for Human Use communicated a negative trend vote on the neratinib. The development makes it unlikely that a positive opinion is coming in February, Kasimov tells investors in a research note. He calls the news "unexpected and clearly disappointing" and suspects it will represent another hit to sentiment. After speaking to management, however, the analyst finds it possible that the European review can get back on track. Puma plans to file for re-examination, which would yield a new opinion in four months, Kasimov notes. Nonetheless, he removed European Nerlynx sales from his model. He continues to see value in the U.S. opportunity alone at current share levels and keeps an Overweight rating on Puma Biotechnology.
01/24/18
RBCM
01/24/18
NO CHANGE
Target $77
RBCM
Sector Perform
Puma Biotechnology price target lowered to $77 from $108 at RBC Capital
RBC Capital analyst Kennen MacKay lowered his price target on Puma Biotechnology to $77 following a CHMP negative trend vote disclosure that suggests a negative CHMP opinion for neratinib's extended adjuvant MAA at the February CHMP meeting. The analyst says the CHMP requests for additional data are surprising based on his recent conversations with the management. MacKay keeps his Sector Perform rating on Puma Biotechnology.
01/24/18
FBCO
01/24/18
NO CHANGE
Target $106
FBCO
Outperform
Puma Biotechnology price target lowered to $106 from $147 at Credit Suisse
Credit Suisse analyst Alethia Young lowered her price target for Puma Biotechnology to $106 from $147 to reflect increased risk around the EU approval process. The analyst notes that she was "very surprised" to hear that the EMA oral hearing concluded that single trial data on invasive disease-free survival benefits seen over 3 and 5 years may not be clinically relevant. However, Young believes the company will file for re-examination in the near future. She reiterates an Outperform rating on the shares.
02/15/18
SBSH
02/15/18
NO CHANGE
Target $146
SBSH
Buy
Puma Biotechnology added to U.S. Focus List at Citi
Citi analyst Yigal Nochomovitz added Puma Biotechnology to his firm's U.S. Focus List citing "high conviction" on the name and the Nerlynx launch in breast cancer. Even with yesterday's 11% rally, the stock is trading at roughly 10 times the 2018 consensus Nerlynx revenue estimate of $220M and two times a peak U.S. sales estimate of $1.1B, Nochomovitz tells investors in a research note . He believes Puma's U.S. opportunity alone is worth $90 per share. The analyst keeps a Buy rating on the shares with a $146 price target.

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