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ASMB

Assembly Biosciences

$50.29

3.63 (7.78%)

05:32
04/12/18
04/12
05:32
04/12/18
05:32

Assembly Biosciences presents interim data from ABI-H0731 Phase 1a, 1b studies

Assembly Biosciences presented interim results from Phase 1a and 1b study of ABI-H0731, a novel antiviral in development for the treatment of chronic HBV infection, in a "late-breaker" poster presentation at The International Liver Congress, the Annual Meeting of the European Association for the Study of the Liver, or EASL. A copy of the poster can be found at assemblybio.com on the "Events & Presentations" page under "Investors." The late-breaker poster outlines interim data from the ongoing Phase 1b antiviral efficacy study and a recently completed Phase 1a safety and pharmacokinetic, or PK, study of ABI-H0731, a novel, oral Core protein Allosteric Modifier, or CpAM, with selective and potent activity against all major HBV genotypes. To date, two cohorts of HBV patients have completed dosing in the Phase 1b trial, in addition to three additional cohorts in a Phase 1a study in healthy volunteers. A third HBV patient cohort receiving 300 mg is ongoing, though only initial results are reported. Two HBeAg negative patients have also been treated at 400 mg.

  • 12

    Apr

ASMB Assembly Biosciences
$50.29

3.63 (7.78%)

03/08/18
JEFF
03/08/18
NO CHANGE
Target $75
JEFF
Buy
Assembly Biosciences price target raised to $75 from $50 at Jefferies
Jefferies analyst Michael Yee raised his price target for Assembly Biosciences to $75 and keeps a Buy rating on the shares. The analyst continues to like Assembly as a top smid-cap biotech idea given "emerging promising data" for core protein inhibitors in Hepatitis B, its "own strong and growing" pipeline with data catalysts this year, and "significant" market opportunity. Further, the analyst sees the company's $120M cash position as sufficient to move beyond 2018 and fund large Phase II studies.
01/15/18
JEFF
01/15/18
NO CHANGE
Target $50
JEFF
Buy
Assembly Biosciences offers 'compelling' upside opportunity, says Jefferies
Jefferies analyst Michael Yee says Assembly Biosciences offers a "compelling asymmetric upside opportunity" given the company's potential for a functional cure in a multi-billion dollar opportunity in Hepatitis B. The analyst thinks Assembly's upcoming Phase IB data should show "positive and potent" antiviral responses and clean safety, further de-risking the program into Phase II. Yee keeps a Buy rating on the shares with a $50 price target.
01/05/18
RILY
01/05/18
INITIATION
Target $35
RILY
Neutral
Assembly Biosciences initiated with a Neutral at B. Riley FBR
B. Riley FBR analyst Madhu Kumar started Assembly Biosciences with a Neutral rating and $35 price target.
11/08/17
11/08/17
INITIATION

On The Fly: Top analyst initiations
Catch up on today's top analyst initiations with this list compiled by The Fly: 1. Abeona Therapeutics (ABEO) initiated with a Buy at SunTrust. 2. Cogentix Medical (CGNT) resumed with a Buy at Roth Capital. 3. Accenture (ACN) and Cognizant (CTSH) were initiated with a Buy at Pivotal Research. 4. Assembly Biosciences (ASMB) initiated with a Buy at Jefferies. This list is just a portion of The Fly's analyst coverage. To see The Fly's full Street Research coverage, click here.

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