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AGLE

Aeglea BioTherapeutics

$10.36

0.68 (7.02%)

07:54
04/13/18
04/13
07:54
04/13/18
07:54

Aeglea BioTherapeutics price target raised to $20 from $12 at Needham

Needham analyst Chad Messer raised his price target on Aeglea BioTherapeutics to $20 after the company's Phase 1/2 study presentation for pegzilarginase in Arginase 1 Deficiency at the American College of Medical Genetics and Genomics meeting. Messer points to "significant improvements in multiple parameters" for 2 patients after they completed just 8 weeks of dosing, which should "substantially de-risk" the ARG1-D program going forward. The analyst expects a multi-dose readout in Q3 and a pivotal study design to be completed by the end of this year while forecasting a commercial launch in late 2020. Messer also keeps his Buy rating on Aeglea BioTherapeutics.

  • 21

    May

AGLE Aeglea BioTherapeutics
$10.36

0.68 (7.02%)

03/14/18
BMOC
03/14/18
NO CHANGE
Target $18
BMOC
Outperform
Aeglea BioTherapeutics price target lowered to $18 from $21 at BMO Capital
BMO Capital analyst M. Ian Somaiya lowered his price target on Aeglea BioTherapeutics to $18, updating his model to reflect the cash burn associated with the Phase 3 trial of ARG1-D. The analyst keeps his Outperform rating after the latest data in two patients showed a "near normalization of arginine levels (as) the magnitude of these reductions has never been achieved before using conventional diet-control/ammonia scavengers" method. Somaiya looks ahead to the company's April 12th presentation on ARG1-D at the ACMG Annual Clinical Genetics Meeting.
03/14/18
NEED
03/14/18
NO CHANGE
Target $12
NEED
Buy
Aeglea BioTherapeutics price target raised to $12 from $8 at Needham
Needham analyst Chad Messer raised his price target on Aeglea BioTherapeutics to $12 after the company's presentation on ARG1-D at the annual SIMD meeting that showed two adult patients dosed for 8 weeks demonstrate sustained reductions of arginine at or near normal levels. Messer keeps his Buy rating, stating that the company's $50M in cash is sufficient to reach Q3 of 2019 and get past the full multi-dose data and Phase III trial design, while also noting progress in Aeglea's oncology program.
04/13/18
WELS
04/13/18
NO CHANGE
WELS
Outperform
Wells Fargo increasingly confident on Aeglea's pegzilarginase
Wells Fargo analyst Jim Birchenough reiterates an Outperform rating on shares of Aeglea BioTherapeutics following a call with senior management. The analyst has increased confidence on pegzilarginase's clinical results and the potential positive implications for a de-risked regulatory path. He continues to believe that Aeglea's orphan drug opportunity has been underestimated and sees further upside on additional updates expected in the second half of 2018. Birchenough keeps a $24 price target for the shares.

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