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CALA

Calithera Biosciences

$6.00

0.05 (0.84%)

08:40
04/13/18
04/13
08:40
04/13/18
08:40

Calithera to present preclinical research for its glutaminase inhibitor CB-839

Calithera Biosciences announced that preclinical research for its glutaminase inhibitor CB-839 will be shared as poster presentations at the American Association for Cancer Research Annual Meeting 2018 in Chicago. CB-839 is a potent, selective, orally bioavailable glutaminase inhibitor in Phase 2 trials. The company and its academic collaborators will highlight data of CB-839 in novel therapeutic combinations in preclinical models of selected cancers."Tumor metabolism is a novel therapeutic approach that exploits the way in which cancer cells utilize nutrients to grow and survive," said Susan Molineaux, PhD, President and Chief Executive Officer of Calithera. "CB-839, a novel glutaminase inhibitor, has the potential to be developed in combination with standard of care cancer therapeutics such as CDK4/6 or PARP inhibitors to improve patient outcomes."

CALA Calithera Biosciences
$6.00

0.05 (0.84%)

06/12/17
HCWC
06/12/17
NO CHANGE
Target $19
HCWC
Buy
Calithera Biosciences price target raised to $19 from $14 at H.C. Wainwright
H.C. Wainwright analyst Shaunak Deepak raised his price target for Calithera Biosciences to $19 saying data suggest CB-1158 "demonstrates promising arginase inhibition." The analyst believes that twice-daily CB-1158 can effectively reduce arginase activity, resulting in "meaningful increases in plasma arginine activity and preliminary evidence of immune modulation." He keeps a Buy rating on Calithera.
10/05/17
WBLR
10/05/17
INITIATION
WBLR
Outperform
Calithera Biosciences initiated with an Outperform at William Blair
William Blair analyst Matthew Phipps started Calithera Biosciences with an Outperform rating. The analyst sees clinical catalysts and a "clear development path" with the company's wholly owned glutaminase inhibitor, CB-839, driving share outperformance in the coming months.
02/16/18
SBSH
02/16/18
UPGRADE
Target $14
SBSH
Buy
Calithera Biosciences upgraded to Buy from Neutral at Citi
Citi analyst Robyn Karnauskas upgraded Calithera Biosciences (CALA) to Buy with an unchanged price target of $14. The stock has been under pressure after Phase 1 data from the CB-839/PD-1 combo, presumably due to comparison to Nektar Therapeutics' (NKTR) combo data, Karnauskas tells investors in a research note. She believes this is an unfair comparison, as Calithera and Nektar are targeting different patient populations, and the drugs have different mechanisms. The analyst views Calithera as underappreciated with the stock trading above cash with only $2 per share for the pipeline.

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