Fluidigm unveils introduction of Maxpar for immune cell profiling in cancer
Fluidigm Corporation announced the introduction of the Maxpar Human Immune Monitoring Panel Kit for comprehensive immune cell profiling in cancer and immune-mediated diseases. Immune monitoring is an essential method for quantifying immune cell populations over time in health and disease. It is frequently used in the investigation of chronic inflammation, infectious disease, autoimmune diseases, and cancer. Due to the inherent complexity of the immune system, the number of markers required to identify each subpopulation is continually increasing. Conventional methods used for immune monitoring, however, have a number of limitations. Flow cytometry, for example, often requires the use of complex workflows to design and deploy larger panel sizes, including use of multiple sample and control tubes that can exhaust precious biological samples and increase antibody usage. In addition, highly complex and time-consuming data analysis methods are needed to deconvolute fluorescence signals and subtract cellular autofluorescence that can interfere with results. Designed for use with the Helios, a CyTOF system, the Maxpar Human Immune Monitoring Panel Kit is offered as a proven mass cytometry workflow to meet these challenges. Representing a significant step forward in high-parameter immune profiling, the immune monitoring kit contains 29 metal-labeled antibodies and reagents designed and optimized for deep immune profiling of human PBMC in a single tube. Optimized for routine high-parameter immune profiling, panel biomarkers were selected in collaboration with industry-leading pharmaceutical companies and academic institutions. Preserving precious samples, the single-tube assay enables combinatorial information to be obtained from each sample, eliminates daughter tube variation, and offers a simplified workflow that significantly reduces hands-on time.