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ZYME

Zymeworks

$11.95

-0.03 (-0.25%)

, CELG

Celgene

$89.55

0.61 (0.69%)

16:06
04/23/18
04/23
16:06
04/23/18
16:06

Zymeworks, Celgene expand bispecific antibody collaboration

Zymeworks (ZYME) announced that Celgene (CELG) has exercised its right to expand its collaboration agreement for the research, development, and commercialization of bispecific antibody therapeutics using Zymeworks' Azymetric platform. Under the terms of the original collaboration agreement signed in 2014 which enabled Celgene to research and develop multiple bispecific antibodies based on the Azymetric platform, Celgene has now exercised its right to increase the number of potential products it can develop and commercialize from eight to ten, and extended the research program term by two years. Zymeworks will receive an expansion fee and is now eligible to receive up to $164M in development and commercial milestones for each of up to 10 products plus royalties on worldwide sales. In total, Zymeworks is now eligible to receive up to $1.64B in future payments for the entire collaboration.

ZYME

Zymeworks

$11.95

-0.03 (-0.25%)

CELG

Celgene

$89.55

0.61 (0.69%)

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    May

ZYME Zymeworks
$11.95

-0.03 (-0.25%)

05/24/17
05/24/17
INITIATION

On The Fly: Top five analyst initiations
Catch up on today's top five analyst initiations with this list compiled by The Fly: 1. Shake Shack (SHAK) initiated with an Overweight at Piper Jaffray. 2. Zymeworks (ZYME) initiated with a Buy at Citi. 3. Murphy Oil (MUR) initiated with a Buy at KLR Group. 4. Atlas Financial (AFH) initiated with an Outperform at JMP Securities. 5. Emerald Expositions Events (EEX) initiated with a Buy at Citi. This list is just a portion of The Fly's analyst coverage. To see The Fly's full Street Research coverage, click here.
09/06/17
LEHM
09/06/17
DOWNGRADE
Target $8
LEHM
Underweight
Zymeworks assumed with an Underweight from Overweight at Barclays
Barclays analyst Gena Wang assumed coverage of Zymeworks and double downgraded the shares to Underweight from the firm's previous rating of Overweight. She cut her price target to $8 from $20. The analyst has low expectations for the company's lead asset HER2 dispecific antibody ZW25 in HER and high and medium expressed breast cancer.
09/07/17
09/07/17
DOWNGRADE

On The Fly: Top five analyst downgrades
Catch up on today's top five analyst downgrades with this list compiled by The Fly: 1. trivago (TRVG) downgraded to Neutral from Buy at BofA/Merrill with analyst Nat Schindler citing a surprise lowering of its 2017 revenue growth target to 40% from 50% and reduced adjusted EBITDA to down year-over-year. 2. Carrizo Oil & Gas (CRZO) downgraded to Neutral from Buy at Mizuho with analyst Timothy Rezvan saying Carrizo faces too many near-term headwinds and doesn't see Net Asset Value upside driving near-term stock outperformance. 3. Varian Medical (VAR) downgraded on valuation, macro concerns at BTIG with analyst Sean LAvin saying he downgraded the stock "mainly on valuation." However, he also believes that the company's results could be hurt by "instability in Korea and multiple hurricanes." 4. Zymeworks (ZYME) assumed with an Underweight from Overweight at Barclays with analyst Gena Wang saying she has low expectations for the company's lead asset HER2 dispecific antibody ZW25 in HER and high and medium expressed breast cancer. 5. Sealed Air (SEE) downgraded to Neutral from Buy at Citi with analyst Anthony Pettinari saying the company's annual guidance is at risk due to resin headwinds post Hurricane Harvey. This list is just a portion of The Fly's full analyst coverage. To see The Fly's full Street Research coverage, click here.
03/19/18
RAJA
03/19/18
INITIATION
Target $18
RAJA
Outperform
Zymeworks initiated with an Outperform at Raymond James
Raymond James analyst David Novak initiated Zymeworks with an Outperform and $18 price target telling investors the company represents "Canada's Mother Of All Biotechnology plays" given its robust platform technologies which have significant partner interest, and a growing pipeline of wholly owned assets. .
CELG Celgene
$89.55

0.61 (0.69%)

04/03/18
JMPS
04/03/18
NO CHANGE
JMPS
Market Perform
Celgene COO departure not a surprise, says JMP Securities
JMP Securities analyst Michael King said he was not surprised by the announcement that Celgene COO Scott Smith is exiting given the recent missteps in the company's Inflammation and Immunology franchise. This appears to be the first major step in restructuring Celgene's executive team and he hopes the evolving management structure improves execution and accountability, King tells investors. Although valuation seems to be at extreme lows, King thinks Celgene shares will have a hard time recovering until the company can demonstrate it has regained its ability to drive value, either through execution or an acquisition. He keeps a Market Perform rating on the stock.
04/13/18
MSCO
04/13/18
INITIATION
Target $93
MSCO
Equal Weight
Celgene resumed with an Equal Weight at Morgan Stanley
Morgan Stanley analyst Matthew Harrison resumed coverage of Celgene with an Equal Weight rating and $93 price target, as he sees potential upside from cell therapies and luspatercept being balanced by the key risks that remain for both the ozanimod and fedratinib filings.
04/13/18
04/13/18
INITIATION

On The Fly: Top five analyst initiations
Catch up on today's top five analyst initiations with this list compiled by The Fly: 1. Dropbox (DBX) initiated with a Reduce at Nomura Instinet. 2. Horizon Global (HZN) initiated with a Buy at B. Riley FBR. 3. Sonoco Products (SON) initiated with a Buy at UBS. 4. Campbell Soup (CPB) reinstated with a Sell at Goldman Sachs. 5. Celgene (CELG) resumed with an Equal Weight at Morgan Stanley. This list is just a portion of The Fly's analyst coverage. To see The Fly's full Street Research coverage, click here.
04/23/18
04/23/18
DOWNGRADE
Target $12

Hold
Prothena downgraded to Hold with $12 target after NEOD001 failure at Jefferies
As previously reported, Jefferies analyst Michael Yee downgraded Prothena (PRTA) to Hold from Buy and lowered his price target to $12 from $100 after the NEOD001 AL amyloidosis program was discontinued following the failure of the Phase 2 PRONTO study. The focus now shifts to its early pipeline assets, which include the Roche-partnered (RHHBY) '002 for Parkinson's and Celgene-partnered (CELG) Neuro program, said Yee. Noting that these early programs will not have data until 2019-20, he believes the stock will be range-bound near its cash level of about $10-$12 per share.

TODAY'S FREE FLY STORIES

ENIA

Enel Americas

$9.25

-0.08 (-0.86%)

19:01
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Upgrade
Enel Americas rating change at Goldman Sachs »

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UL

Unilever; also tag UN

$54.26

0.64 (1.19%)

, UN

Unilever; also tag UL

$54.74

0.7 (1.30%)

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UL

Unilever; also tag UN

$54.26

0.64 (1.19%)

UN

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$54.74

0.7 (1.30%)

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TWX

Time Warner

$98.91

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, CMCSA

Comcast

$33.85

0.03 (0.09%)

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TWX

Time Warner

$98.91

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CMCSA

Comcast

$33.85

0.03 (0.09%)

CMCSK

Comcast

$0.00

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SNE

Sony

$49.11

-0.02 (-0.04%)

FOX

21st Century Fox

$44.57

0.14 (0.32%)

FOXA

21st Century Fox

$44.60

0.03 (0.07%)

LGF.A

Lionsgate

$26.57

1.52 (6.07%)

DIS

Disney

$108.91

0.15 (0.14%)

VIAB

Viacom

$29.40

0.49 (1.69%)

VIA

Viacom

$33.95

0.15 (0.44%)

03/08/13
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OAS

Oasis Petroleum

$12.01

-0.63 (-4.98%)

, OMP

Oasis Midstream Partners

$17.29

-1.02 (-5.57%)

16:46
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Conference/Events
JPMorgan to hold a conference »

3rd Annual Energy Equity…

OAS

Oasis Petroleum

$12.01

-0.63 (-4.98%)

OMP

Oasis Midstream Partners

$17.29

-1.02 (-5.57%)

SRCE

1st Source

$55.36

0.13 (0.24%)

LGCY

Legacy Reserves

$6.07

-0.03 (-0.49%)

EVA

Enviva

$29.35

0.15 (0.51%)

CRC

California Resources

$35.03

-2.57 (-6.84%)

INSM

Insmed

$26.74

-1.5 (-5.31%)

03/08/13
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  • 18

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16:43
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Leerink to hold a tour »

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GM

General Motors

$43.91

0.32 (0.73%)

, FCAU

Fiat Chrysler

$20.86

-0.37 (-1.74%)

16:38
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Periodicals
Automakers putting smaller engines into big trucks, WSJ reportsFord »

U.S. auto makers are…

GM

General Motors

$43.91

0.32 (0.73%)

FCAU

Fiat Chrysler

$20.86

-0.37 (-1.74%)

F

Ford

$11.88

-0.01 (-0.08%)

03/08/13
Wedge Partners
03/08/13
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03/06/13
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03/06/13
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MSFT

Microsoft

$100.24

-1.14 (-1.12%)

, GOOGL

Alphabet Class A

$1,159.03

-1.08 (-0.09%)

16:34
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Periodicals
Microsoft is fixing office, WSJ reports »

The new version of…

MSFT

Microsoft

$100.24

-1.14 (-1.12%)

GOOGL

Alphabet Class A

$1,159.03

-1.08 (-0.09%)

GOOG

Alphabet

$1,151.95

-0.05 (-0.00%)

03/08/13
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03/06/13
Citigroup
03/06/13
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  • 18

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    Oct

16:34
06/17/18
06/17
16:34
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16:34
Conference/Events
Deutsche Bank to hold a conference »

Taiwan Auto Electronics…

WFC

Wells Fargo

$54.99

0.23 (0.42%)

, MS

Morgan Stanley

$51.17

-0.12 (-0.23%)

16:33
06/17/18
06/17
16:33
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Conference/Events
Federal Reserve Bank of New York to hold a conference »

Reforming Culture &…

WFC

Wells Fargo

$54.99

0.23 (0.42%)

MS

Morgan Stanley

$51.17

-0.12 (-0.23%)

BAC

Bank of America

$29.27

-0.24 (-0.81%)

C

Citi

$66.34

0.18 (0.27%)

WBK

Westpac Banking

$20.67

0.125 (0.61%)

GS

Goldman Sachs

$232.00

-1.695 (-0.73%)

BCS

Barclays

$10.59

-0.225 (-2.08%)

03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
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F

Ford

$11.88

-0.01 (-0.08%)

16:25
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Ford acquires Michigan Central Station »

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BMY

Bristol-Myers

$54.81

1.165 (2.17%)

16:22
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Bristol-Myers' ELOQUENT-3 trial meets primary endpoint »

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  • 26

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PTCT

PTC Therapeutics

$37.57

-0.75 (-1.96%)

, RHHBY

Roche

$0.00

(0.00%)

16:18
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PTC Therapeutics presents updated preliminary data from SMA FIREFISH Program »

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PTCT

PTC Therapeutics

$37.57

-0.75 (-1.96%)

RHHBY

Roche

$0.00

(0.00%)

03/08/13
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CYTK

Cytokinetics

$9.95

0.5 (5.29%)

16:15
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Cytokinetics announces data from Phase 2 clinical study of Reldesemtiv in SMA »

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PERY

Perry Ellis

$27.92

0.31 (1.12%)

16:12
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Hot Stocks
Perry Ellis enters into $437M transaction to become private company »

Perry Ellis International…

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VSTM

Verastem

$6.53

0.95 (17.03%)

16:08
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Verastem presents duvelisib data at EHA 2018 annual meeting »

Verastem announced one…

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  • 05

    Oct

IQ

iQIYI

$40.16

-0.44 (-1.08%)

16:05
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iQIYI obtains broadcasting rights for all four golf majors »

iQIYI announced it had…

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HD

Home Depot

$200.55

0.86 (0.43%)

15:56
06/17/18
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Conference/Events
Home Depot participates in a field trip with UBS »

Field Trip to Atlanta, GA…

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PAY

Verifone

$22.84

0.01 (0.04%)

15:28
06/17/18
06/17
15:28
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15:28
Conference/Events
Verifone to host special shareholder meeting »

Special Shareholder…

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CACI

CACI

$167.60

1.1 (0.66%)

14:18
06/17/18
06/17
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14:18
Conference/Events
CACI to hold a webcast »

Management discusses…

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  • 21

    Jun

ARGX

Argenx

$92.38

-3.32 (-3.47%)

14:11
06/17/18
06/17
14:11
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Conference/Events
Argenx to hold a KOL breakfast symposium »

Management holds a Key…

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  • 20

    Jun

PTC

PTC

$94.87

-0.46 (-0.48%)

14:06
06/17/18
06/17
14:06
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14:06
Conference/Events
PTC to host analyst day »

Analyst Day to be held in…

03/08/13
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13:41
06/17/18
06/17
13:41
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13:41
Conference/Events
Federal Reserve Bank of Atlanta president speaks at a meeting »

Atlanta Federal Reserve…

VRX

Valeant

$26.86

0.06 (0.22%)

13:31
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06/17
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13:31
Conference/Events
Breaking Conference/Events news story on Valeant »

FDA PDUFA Date for…

03/08/13
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  • 18

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WMGI

Wright Medical

$25.83

-0.26 (-1.00%)

13:27
06/17/18
06/17
13:27
06/17/18
13:27
Conference/Events
Wright Medical management to meet with Leerink »

Meeting to be held on…

03/08/13
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