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IONS

Ionis Pharmaceuticals

$43.68

-0.7 (-1.58%)

13:45
05/16/18
05/16
13:45
05/16/18
13:45

Ionis Pharmaceuticals has a conferenced call hosted by JPMorgan

JPMorgan Analyst Fye will host a conference call with COO Brett Monia on May 16 at 2 pm.

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    Oct

IONS Ionis Pharmaceuticals
$43.68

-0.7 (-1.58%)

05/08/18
05/08/18
DOWNGRADE

On The Fly: Top five analyst downgrades
Catch up on today's top five analyst downgrades with this list compiled by The Fly: 1. Comcast (CMCSA) downgraded to Neutral from Overweight at Atlantic Equities. 2. Zillow (Z, ZG) downgraded to Sector Perform from Outperform at RBC Capital with analyst Mark Mahaney citing the recent stock price appreciation. 3. XL Group (XL) downgraded to Sector Perform from Outperform at RBC Capital with analyst Mark Dwelle saying the company's first quarter earnings did not contain any red flags around the sale of the company to AXA (AXAHY), which is on track to close in late second quarter or in the third quarter. 4. Ionis Pharmaceuticals (IONS) downgraded to In Line from Outperform at Evercore ISI with analyst Josh Schimmer citing the safety concerns around volanesorsen discussed in the latest FDA briefing documents, which also "dismantled the company's claims" that the treatment leads to benefits in pancreatis. 5. Sapiens (SPNS) downgraded to Market Perform from Outperform at William Blair with analyst Justin Furby saying consensus estimates for 2019 could be a "too aggressive." This list is just a portion of The Fly's full analyst coverage. To see The Fly's full Street Research coverage, click here.
05/08/18
EVER
05/08/18
DOWNGRADE
Target $46
EVER
In Line
Ionis Pharmaceuticals cut to In Line at Evercore ISI after volanesorsen review
As reporter earlier, Evercore ISI analyst Josh Schimmer downgraded Ionis Pharmaceuticals to In Line from Outperform and lowered his price target to $46 from $55. The analyst cites the safety concerns around volanesorsen discussed in the latest FDA briefing documents, which also "dismantled the company's claims" that the treatment leads to benefits in pancreatis. Schimmer says that while he did not assign much value around volanesorsen, he is now removing it from the model until there is more certainty around the drug profile while also increasing the discount rate to reflect additional platform uncertainty.
05/08/18
EVER
05/08/18
DOWNGRADE
EVER
In Line
Ionis Pharmaceuticals downgraded to In Line from Outperform at Evercore ISI
04/24/18
EVER
04/24/18
NO CHANGE
EVER
Outperform
Spinraza decline in new adds happened 'a bit early,' says Evercore ISI
Commenting on weakness in shares of Ionis Pharmaceuticals (IONS), Evercore ISI analyst Josh Schimmer said he knew Spinraza new adds would start to decline at some point, leading to a sequential drop in injections, but this happened "a bit early." Following Biogen's (BIIB) report, he sees potential for Spinraza stagnation in the U.S. this year, with growth driven outside of the U.S. In terms of the Huntington's data for Ionis' antisense program partnered with Roche (RHHBY) presented today, Schimmer said there were "encouraging signs for some of the disease measures, less encouraging for others" along with "generally wide error bars." He has an Outperform rating on Ionis, which is down 11% to $45.06 in afternoon trading.

TODAY'S FREE FLY STORIES

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AMX

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America Movil, also tag AMX

$15.03

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ABT

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0.44 (0.87%)

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ADTN

Adtran

$18.15

1.08 (6.33%)

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Adtran reports Q3 adjusted EPS 21c, consensus 4c »

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WAFD

Washington Federal

$29.75

0.45 (1.54%)

20:02
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Washington Federal reports Q4 EPS 62c, consensus 62c »

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UNH

UnitedHealth

$272.24

12.44 (4.79%)

19:30
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Recommendations
UnitedHealth analyst commentary at Piper Jaffray »

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  • 16

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CDAY

Ceridian

$38.44

1.38 (3.72%)

19:25
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Ceridian to hold a conference »

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HMC

Honda

$27.70

0.65 (2.40%)

19:07
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Honda Aircraft sees higher light jet deliveries next year, Reuters says »

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  • 24

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VALE

Vale

$15.50

0.045 (0.29%)

18:59
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Vale plans to use cash flow cautiously going forward, Reuters says »

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VICR

Vicor Corporation

$38.35

1.42 (3.85%)

, NFLX

Netflix

$346.40

13.29 (3.99%)

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Fly Intel: After Hours Movers »

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AMAT

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$34.76

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UAL

United Continental

$83.51

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FULT

Fulton Financial

$16.39

0.29 (1.80%)

CSX

CSX

$72.15

1.29 (1.82%)

CREE

Cree

$37.56

2.53 (7.22%)

ROKU

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1.97 (3.19%)

IBM

IBM

$145.02

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UFPI

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SONC

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EIGR

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SBH

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0.42 (2.27%)

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NFLX

Netflix

$346.40

13.29 (3.99%)

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Netflix says it has a 'long, long runway' in India »

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CBL

CBL & Associates

$3.52

0.085 (2.48%)

, SHLD

Sears

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  • 30

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VZ

Verizon

$53.68

0.08 (0.15%)

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Verizon says Bay, Gulf counties customers to be credited 3 months of service »

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  • 12

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BMO

Bank of Montreal

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Bank of Montreal names Wolford investment banking vice chair, Reuters says »

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  • 24

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SFTBF

SoftBank

$0.00

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SoftBank COO says 'anxiously' looking at Saudi Arabia situation, Reuters says »

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  • 16

    Oct

IBM

IBM

$145.02

3.9 (2.76%)

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IBM sees growth in cloud overall »

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CELC

Celcuity

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Celcuity, Puma Biotechnology and West Cancer Center to conduct Phase 2 trial »

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  • 19

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DVN

Devon Energy

$37.08

0.98 (2.71%)

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VIA

Viacom

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Viacom launches Nickelodeon Chinese Animation Development Project, Variety says »

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VIA

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$36.07

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VIAB

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IQ

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  • 16

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BHP

BHP Billiton

$48.48

0.38 (0.79%)

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BHP Billiton reports Q1 iron ore output 61.4M tons, up 10% from last year »

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UBER

Uber

$0.00

(0.00%)

17:37
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Uber increases junk-bond offering to $2B, Bloomberg says »

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IBM

IBM

$145.02

3.9 (2.76%)

17:32
10/16/18
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IBM says growth was led by hybrid cloud, analytics and AI, digital and security »

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  • 16

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  • 03

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NDAQ

Nasdaq

$81.93

1.91 (2.39%)

, ICE

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$74.95

2.18 (3.00%)

17:31
10/16/18
10/16
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17:31
Hot Stocks
SEC confirms ruling that Nasdaq, NYSE didn't justify rate increases »

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NDAQ

Nasdaq

$81.93

1.91 (2.39%)

ICE

IntercontinentalExchange

$74.95

2.18 (3.00%)

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  • 24

    Oct

IAU

iShares Gold Trust

$11.74

-0.005 (-0.04%)

17:28
10/16/18
10/16
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17:28
Syndicate
Breaking Syndicate news story on iShares Gold Trust »

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VICR

Vicor Corporation

$38.35

1.42 (3.85%)

17:26
10/16/18
10/16
17:26
10/16/18
17:26
Earnings
Vicor Corporation reports Q3 EPS 32c vs. 0c in Q317 »

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  • 18

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