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BLRX

BioLineRx

$0.89

0.0726 (8.90%)

09:05
05/17/18
05/17
09:05
05/17/18
09:05

BioLineRx reports Phase 2 results on BL-8040 for stem cell mobilization

BioLineRx announced "positive" results from a Phase 2 clinical trial assessing BL-8040 as a single agent for hematopoietic stem cell mobilization in an allogeneic transplantation setting. Mobilization of hematopoietic stem and progenitor cells for the purpose of donor transplantation after high-dose chemotherapy is currently performed using a 4-5 day treatment cycle with G-CSF and a 1-2 day apheresis procedure. Single-agent treatment with BL-8040, a novel, high-affinity CXCR4 antagonist with rapid HSPC mobilizing kinetics, showed similar efficacy in only one administration. In addition, BL-8040 showed non-inferiority in recipient engraftment, with all transplanted recipients successfully engrafting with BL-8040-mobilized grafts. Of the 21 evaluable donors that have been enrolled in the study to date, 11 out of 13 donors, 85%, treated at the 1 mg/kg dose and 8/8 donors, 100%, treated at the 1.25 mg/kg dose of BL-8040 reached the primary goal of greater than or equal to2x106 CD34 cells/kg of recipient weight in up to 2 leukapheresis sessions. BL-8040 was safe and well tolerated. 13 transplanted recipients have reached the secondary endpoint of 100 days post-transplant. Results of the lead-in period from the Phase 3 trial are expected in the next few months.

  • 22

    May

BLRX BioLineRx
$0.89

0.0726 (8.90%)

05/18/17
MAXM
05/18/17
UPGRADE
Target $3
MAXM
Buy
BioLineRx upgraded to Buy from Hold at Maxim
Maxim analyst Jason Kolbert upgraded BioLineRx to Buy from Hold as the company is now closer to being a pivotal company after announcing it will initiate a Phase 3 program for BL-8040 in stem cell mobilization later this year. Kolbert, who believes the stock can start to outperform in 2017, raised his price target on BioLineRx to $3 from $1.
05/18/17
05/18/17
UPGRADE

On The Fly: Top five analyst upgrades
Catch up on today's top five analyst upgrades with this list compiled by The Fly: 1. Progressive (PGR) upgraded to Hold from Sell at Deutsche Bank with analyst Joshua Shanker saying his concerns over the company's margins "are not longer apt" and that sees no catalyst to the downside. 2. Shake Shack (SHAK) upgraded to Outperform from Neutral at Wedbush with analyst Nick Setyan saying the valuation at current share levels is attractive given Shake Shack's "industry-leading growth trajectory. 3. CarMax (KMX) upgraded to Outperform from Neutral at Wedbush with analyst Seth Basham saying the company's CAF credit losses will probably rise less in 2017 than in 2016, reducing "the risk of a credit-driven blowout." 4. Bank of Montreal (BMO) upgraded to Buy from Neutral at Citi with analyst Ian Sealey citing the recent pullback in the shares of Canadian banks as he sees "strong" book value and dividend growth over the longer term. 5. BioLineRx (BLRX) upgraded to Buy from Hold at Maxim with analyst Jason Kolbert saying the company is now closer to being a pivotal company after announcing it will initiate a Phase 3 program for BL-8040 in stem cell mobilization later this year. This list is just a portion of The Fly's full analyst coverage. To see The Fly's full Street Research coverage, click here.
08/03/17
OPCO
08/03/17
INITIATION
Target $3
OPCO
Outperform
BioLineRx initiated with an Outperform at Oppenheimer
Oppenheimer analyst Mark Breidenbach initiated BioLineRx with a $3 price target saying its lead asset, BL-8040, could could unseat Sanofi's plerixafor as the preferred agent to combine with G-CSF for mobilizing stem cells in autologous hematopoietic stem cell transplants and said its Phase 3 GENESIS trial in the second half has a high probability of success.
03/06/18
HCWC
03/06/18
NO CHANGE
HCWC
H.C. Wainwright sees several second half data catalysts for BioLineRx
H.C. Wainwright analyst Joseph Pantginis noted that BioLineRx's Q4 and FY17 financial results missed the firm's estimates slightly, but he was optimistic about the company's second half data catalysts -- including topline results from COMBAT, lead-in stage results for the Phase 3 GENESIS study, partial results from Phase 1b/2 studies for BL-8040 in combination with Tecentriq in gastric cancer, NSCLC, and AML, as well as data from multiple other studies. Pantginis reiterated a Buy rating and has a $4 price target on BioLineRx shares.

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AAPL

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CAT

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0.38 (0.24%)

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BSX

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OHGI

One Horizon Group

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-0.0088 (-4.63%)

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CYTX

Cytori Therapeutics

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NEM

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CB

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VTVT

vTv Therapeutics

$0.80

0.0096 (1.21%)

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