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VYGR

Voyager Therapeutics

$20.34

0.12 (0.59%)

18:19
05/17/18
05/17
18:19
05/17/18
18:19

Voyager Therapeutics announces VY-SOD101 data at ASGCT

Voyager Therapeutics announced new data presentations at the American Society of Gene and Cell Therapy taking place May 16-19, 2018, in Chicago, Ill. Voyager presented results for VY-SOD101, which targets the superoxide dismutase 1 gene, the first mutant gene discovered to be causal for the development of amyotrophic lateral sclerosis. The results demonstrated that a one-time administration of VY-SOD101 lowered SOD1 mRNA levels by 78% in the spinal cord motor neurons of non-human primates. Additional new data at this year's ASGCT meeting included tolerability data in non-human primates for VY-HTT01 for Huntington's disease, along with previous data with VY-HTT01 that demonstrated a 54% suppression of huntingtin mRNA in the non-human primate putamen after a single administration. Presentations at ASGCT also included comparability data between Voyager's baculovirus/Sf9 and HEK293 triple transfection manufacturing systems.

  • 18

    May

VYGR Voyager Therapeutics
$20.34

0.12 (0.59%)

04/10/18
ADAM
04/10/18
NO CHANGE
Target $35
ADAM
Buy
AveXis takeout positive for Voyager Therapeutics, says Canaccord
Canaccord analyst Sumant Kulkarni believes AveXis' (AVXS) buyout by Novartis (NVS) is a sign big pharma is willing to make big bets in the gene therapy space. The analyst is encouraged by the neuroscience focus of the deal and he believes that bodes well for Voyager Therapeutics (VYGR), as some of its programs are at similar stages of development. Kulkarni has a Buy rating and $35 price target on Voyager Therapeutics shares.
04/18/18
BERN
04/18/18
NO CHANGE
BERN
Spark Therapeutics, uniQure may be potential takeout targets, says Bernstein
Following AveXis (AVXS) acquisition by Novartis (NVS), Bernstein analyst Vincent Chen says the potential next target should have a strong portfolio fit and innovation-oriented scientifically-minded management teams likely comfortable with the technology platform. For acquisition targets, the analyst sees two flavors, namely late stage more de-risked gene therapy companies, for which Spark (ONCE) comes to mind, and less costly but riskier earlier-stage platforms, for which uniQure (QURE), Voyager (VYGR) and REGENXBIO (RGNX) come to mind.
05/11/18
WEDB
05/11/18
UPGRADE
WEDB
Outperform
Voyager Therapeutics upgraded to Outperform from Neutral at Wedbush
05/11/18
05/11/18
UPGRADE

Outperform
Voyager Therapeutics upgraded to Outperform from Neutral at Wedbush
As previously reported, Wedbush analyst David Nierengarten upgraded Voyager Therapeutics to Outperform from Neutral, but lowered his price target on shares to $28 from $29. The analyst cited valuation, after a sell-off in the stock over the last two months cut the share price nearly in half, including a large dip in the stock on Thursday due to confusing hedging language in Voyager's 10Q filing. Nierengarten said the risk/reward is now more favorable at these levels ahead of the company's pivotal trial start for VY-AADC.

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