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ANIK

Anika Therapeutics

$46.02

0.93 (2.06%)

16:06
06/19/18
06/19
16:06
06/19/18
16:06

Anika Therapeutics announces strong patient response in CINGAL 16-02 trial

Anika Therapeutics announced results from its CINGAL 16-02 clinical trial, an active-comparator Phase III study being conducted to support U.S. registration. CINGAL has previously been evaluated in a placebo-controlled Phase III clinical trial that demonstrated safety and efficacy through 26-weeks. The 16-02 trial compared CINGAL, a combination of cross-linked HA and triamcinolone hexacetonide, with TH alone and cross-linked HA in treating patients with osteoarthritis in the knee. The primary endpoint was a comparison of the pain reduction of CINGAL compared with TH alone at 26-weeks. While CINGAL achieved greater pain reduction numerically at every time point in the study, the difference at 26-weeks did not reach statistical significance. The patient response to CINGAL in the study was strong, as significant improvements in pain, function, and quality of life were observed at levels consistent with, and in most cases greater than, the results of the 13-01 placebo-controlled Phase III study of CINGAL. A strong safety profile was also shown, matching previous clinical studies as well as real-world experience from growing product use globally. The duration of pain reduction was also similar to the previous study as patient improvement after CINGAL injection was maintained near peak levels throughout the 26-week duration of the study. Follow-up of patients continues in a prospectively designed extension phase to the study, which will gather data through 39-weeks.

ANIK Anika Therapeutics
$46.02

0.93 (2.06%)

05/04/18
BRRR
05/04/18
UPGRADE
Target $39
BRRR
Outperform
Anika Therapeutics upgraded to Outperform from Market Perform at Barrington
Barrington analyst Michael Petusky upgraded Anika Therapeutics to Outperform with a $39 price target. Though the stock "deserved to be taken to the proverbial woodshed yesterday" following the Q1 results, the 25% selloff "feels somewhat overdone," Petusky tells investors in a research note. The analyst sees longer-term opportunities for growth and margin expansion.
02/23/18
BRRR
02/23/18
DOWNGRADE
BRRR
Market Perform
Anika downgraded to Market Perform from Outperform at Barrington
Barrington analyst Michael Petusky downgraded Anika Therapeutics to Market Perform saying the shares are near full value following the company's Q4 results. Anika's operating expenses will ramp meaningfully in 2018, reducing near-term profitability and likely capping the share price over the next few quarters, Petusky tells investors in a research note.
01/26/18
SIDC
01/26/18
INITIATION
SIDC
Buy
Anika Therapeutics initiated with a Buy at Sidoti
01/24/18
FANA
01/24/18
UPGRADE
Target $68
FANA
Overweight
Anika Therapeutics upgraded to Overweight from Equal-Weight at First Analysis
First Analysis analyst Joseph Munda upgraded Anika Therapeutics to Overweight and raised his price target for the shares to $68 from $45. A meeting with management gives the analyst confidence that Anika can effectively commercialize products without having to use DePuy Mitek as a marketing partner. In addition to a "deep product pipeline, this osteoarthritis therapy leader has a strong margin profile," Munda tells investors in a research note.

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